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View Structure Prediction Details

Protein: OCH1
Organism: Saccharomyces cerevisiae
Length: 480 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OCH1.

Description E-value Query
Range
Subject
Range
OCH1 - Mannosyltransferase of the cis-Golgi apparatus, initiates the polymannose outer chain elongation of ...
gi|151943252 - gi|151943252|gb|EDN61565.1| alpha-1,6-mannosyltransferase [Saccharomyces cerevisiae YJM789]
OCH1_YEAST - Initiation-specific alpha-1,6-mannosyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / ...
gi|207345301 - gi|207345301|gb|EDZ72167.1| YGL038Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190407003 - gi|190407003|gb|EDV10270.1| alpha-1,6-mannosyltransferase [Saccharomyces cerevisiae RM11-1a]
0.0 [1..480] [1..480]
gi|17978673 - gi|17978673|gb|AAL49987.1| putative mannosyltransferase [Candida albicans]
0.0 [15..472] [12..378]
och1 - alpha-1,6-mannosyltransferase Och1
OCH1_SCHPO - Initiation-specific alpha-1,6-mannosyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24...
8.0E-60 [60..357] [98..335]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-58 [60..357] [68..305]
gi|14161489 - gi|14161489|gb|AAK54761.1| putative mannosyltransferase [Paracoccidioides brasiliensis]
6.0E-42 [88..284] [86..245]
gi|254847069, gi... - gi|75831229|ref|ZP_00760495.1| COG3774: Mannosyltransferase OCH1 and related enzymes [Vibrio cholera...
gi|75828223, gi|... - gi|75828223|ref|ZP_00757658.1| COG3774: Mannosyltransferase OCH1 and related enzymes [Vibrio cholera...
gi|229369129, gi... - gi|229606474|ref|YP_002877122.1| mannosyltransferase OCH1-like enzyme [Vibrio cholerae MJ-1236], gi|...
gi|229516283, gi... - gi|229516283|ref|ZP_04405731.1| mannosyltransferase OCH1 and related enzymes [Vibrio cholerae RC9], ...
gi|229356071, gi... - gi|229506966|ref|ZP_04396474.1| mannosyltransferase OCH1 and related enzymes [Vibrio cholerae BX 330...
gi|9654642, gi|1... - gi|9654642|gb|AAF93410.1| conserved hypothetical protein [Vibrio cholerae O1 biovar El Tor str. N169...
gi|227080454, gi... - gi|227080454|ref|YP_002809005.1| hypothetical protein VCM66_0222 [Vibrio cholerae M66-2], gi|2270083...
gi|11354503 - pir||D82349 conserved hypothetical protein VC0234 [imported] - Vibrio cholerae (strain N16961 serogr...
gi|121586362, gi... - gi|121586362|ref|ZP_01676151.1| conserved hypothetical protein [Vibrio cholerae 2740-80], gi|1215494...
gi|153221445, gi... - gi|153221445|ref|ZP_01952403.1| conserved hypothetical protein [Vibrio cholerae MAK 757], gi|1241196...
gi|126511179, gi... - gi|153818290|ref|ZP_01970957.1| conserved hypothetical protein [Vibrio cholerae NCTC 8457], gi|12651...
gi|229509336, gi... - gi|229509336|ref|ZP_04398819.1| mannosyltransferase OCH1 and related enzymes [Vibrio cholerae B33], ...
7.0E-38 [68..225] [20..179]
gi|108514914, gi... - gi|62868793|gb|AAY17581.1| hypothetical protein [Campylobacter jejuni], gi|167412366|gb|ABZ79826.1| ...
gi|157415409, gi... - gi|157415409|ref|YP_001482665.1| hypothetical protein C8J_1089 [Campylobacter jejuni subsp. jejuni 8...
2.0E-36 [25..221] [4..189]

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Predicted Domain #1
Region A:
Residues: [1-58]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRKLSHLIA TRKSKTIVVT VLLIYSLLTF HLSNKRLLSQ FYPSKDDFKQ TLLPTTSH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
UDP-glycosyltransferase activity 6.01354989568484 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 5.98555597307566 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 5.66606808201136 bayes_pls_golite062009
alpha-1,2-mannosyltransferase activity 5.62955108548526 bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity 5.60505224219681 bayes_pls_golite062009
mannosyltransferase activity 5.1732667004955 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 4.02812104984198 bayes_pls_golite062009
transferase activity 2.3313878748424 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.79751747857925 bayes_pls_golite062009
catalytic activity 1.73979371332125 bayes_pls_golite062009
nucleotidyltransferase activity 1.47767908405723 bayes_pls_golite062009
N-acetyllactosamine synthase activity 0.925872529464618 bayes_pls_golite062009
lactose synthase activity 0.925872529464618 bayes_pls_golite062009
cytidylyltransferase activity 0.450701661234496 bayes_pls_golite062009
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity 0.386636074342689 bayes_pls_golite062009
binding 0.165472828059574 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [59-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQDINLKKQI TVNKKKNQLH NLRDQLSFAF PYDSQAPIPQ RVWQTWKVGA DDKNFPSSFR  60
   61 TYQKTWSGSY SPDYQYSLIS DDSIIPFLEN LYAPVPIVIQ AFKLMPGNIL KADFLRYLLL 120
  121 FARGGIYSDM DTMLLKPIDS WPSQNKSWLN NIIDLNKPI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [218-480]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PYKNSKPSLL SSDEISHQPG LVIGIEADPD RDDWSEWYAR RIQFCQWTIQ AKPGHPILRE  60
   61 LILNITATTL ASVQNPGVPV SEMIDPRFEE DYNVNYRHKR RHDETYKHSE LKNNKNVDGS 120
  121 DIMNWTGPGI FSDIIFEYMN NVLRYNSDIL LINPNLNKND EEGSESATTP AKDVDNDTLS 180
  181 KSTRKFYKKI SESLQSSNSM PWEFFSFLKE PVIVDDVMVL PITSFSPDVG QMGAQSSDDK 240
  241 MAFVKHMFSG SWKEDADKNA GHK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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