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Protein Overview: BNA6

General Information:
Name(s) found: BNA6 / YFR047C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Quinolinate phosphoribosyl transferase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 295 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: NAD biosynthetic process [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: nicotinate-nucleotide diphosphorylase (carboxylating) activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPVYEHLLPV NGAWRQDVTN WLSEDVPSFD FGGYVVGSDL KEANLYCKQD GMLCGVPFAQ  60
   61 EVFNQCELQV EWLFKEGSFL EPSKNDSGKI VVAKITGPAK NILLAERTAL NILSRSSGIA 120
  121 TASHKIISLA RSTGYKGTIA GTRKTTPGLR RLEKYSMLVG GCDTHRYDLS SMVMLKDNHI 180
  181 WATGSITNAV KNARAVCGFA VKIEVECLSE DEATEAIEAG ADVIMLDNFK GDGLKMCAQS 240
  241 LKNKWNGKKH FLLECSGGLN LDNLEEYLCD DIDIYSTSSI HQGTPVIDFS LKLAH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data BNA6 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..118]
    [286..295]    		 PSI-BLAST 398.69897 Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), C-terminal domain; Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), N-terminal domain
    2 View Details [119..170]
    [277..285]    		 PSI-BLAST 398.69897 Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), C-terminal domain; Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), N-terminal domain
    3 View Details [171..276] PSI-BLAST 398.69897 Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), C-terminal domain; Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nicotinate phosphoribosyltransferase activity
    		•  3.4096751090496 bayes_pls_golite062009
  • nicotinate-nucleotide diphosphorylase (carboxylating) activity
    		•  3.12788282156037 bayes_pls_golite062009
  • binding
    		•  1.58263447797054 bayes_pls_golite062009
  • catalytic activity
    		•  0.60409960326459 bayes_pls_golite062009
  • protein binding
    		•  0.502035039039958 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle