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Protein Overview: IRC5

General Information:
Name(s) found: IRC5 / YFR038W [SGD]
Description(s) found:
Found 11 descriptions.
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  • Putative ATPase containing the DEAD/H helicase-related sequence motif; null mutant displays increased levels of spontaneous Rad52p foci [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 778 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRCSNAALM TVVEDAVGAR VAARTRNMSN GVNYREKEVN DLTADISDSD SDLDSEDNKH  60
   61 GKGDNDTAPI WLQDDVHSDE DIQLDSEDDS DTEAVQAQVV DKLAKDTKSE QKSLDDELSE 120
  121 MDTKTVSLKL KKLNEFVRQS QVYSSIIADT LLHRSNEVAN ANTKDNSNSD DEEHSSKKRK 180
  181 TKKKSITDFF KKQKKNEDTT TQNGAPDDAA IKQPRLLKNC ILKPYQLEGL NWLITLYENG 240
  241 LNGILADEMG LGKTVQSIAL LAFIYEMDTK GPFLVTAPLS TLDNWMNEFA KFAPDLPVLK 300
  301 YYGTNGYKER SAKLKNFFKQ HGGTGIVITS YEIILRDTDL IMSQNWKFLI VDEGHRLKNI 360
  361 NCRLIKELKK INTSNRLLLT GTPLQNNLAE LWSLLNFIMP DIFADFEIFN KWFDFDSLNL 420
  421 GSGSNSEALN KLINDELQKN LISNLHTILK PFLLRRLKKV VLANILPPKR EYIINCPMTS 480
  481 AQEKFYKAGL NGKLKKTMFK ELIKDFFTLN DEYIGHVSNR SIRDFINYKL SGNETSNTDN 540
  541 KINPTLLQMD KLYKKNLQME ISNKKLQNMM MQLRQIIDST FLFYFPYLHP EDLTLETLLK 600
  601 TSGKLQILQK LIPPLISEGH KVLIYSQFVN MLDLIEDWCD LNSFATFRID GSVNNETRKD 660
  661 QLEKFNSSKD KHNIFLLSTR AAGLGINLVG ADTVVLFDSD WNPQVDLQAM DRCHRIGQES 720
  721 PVIVYRLCCD NTIEHVILTR AANKRNLERM VIQMGKFNNL KKLALNEGFF FEGKQSGC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..68] deduced N/A No confident structure predictions are available.
    2 View Details [69..162] PSI-BLAST 25.66807 RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain
    3 View Details [163..422] PSI-BLAST 25.66807 RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain
    4 View Details [423..478] deduced N/A No confident structure predictions are available.
    5 View Details [479..778] PSI-BLAST 11.0 Putative DEAD box RNA helicase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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