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Protein Overview: PTR3

General Information:
Name(s) found: PTR3 / YFR029W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 678 amino acids

    Gene Ontology:
    Cellular Component: extrinsic to plasma membrane [IDALink to PubMed article]
    Biological Process: response to amino acid stimulus [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSHRQKWGR QTDIARVLDD IEHDLYLPQR LSLDGATGTD ESHVQYGIVK DCSVLTCGCC  60
   61 ISESLFNDLC RETSNKQTAC PICQRENVRL LSAIKPLRDL ARQIDFFRST TGQGESESDE 120
  121 LPAIVKTSPS SSSLSLTPSR SSSTAGLEAD NKTLSDPTVK EKSSLLELFH IVASKMHNAN 180
  181 TEVGSDHPLT TGTTRDQEEH TTKENYSSSL LEPNYDDHAN WKILDNASNT RTVPIDNNFS 240
  241 LMSTDVTIPS TANYQTNSAH DLDEEKEYFF ANCFPMYRKK FQFNTHPKFL GTKSKLFINQ 300
  301 SISPDCTKFA LITEHKWEIY SINPKDNSPQ LVSCGKSSGE YGPNFNQLTE QSSSSLSTTS 360
  361 QASKKKKKNW SQRFCKLSND FLIISGSQNI LNVHDIHQNG KLIYTYVSRF PIRCIDIDPR 420
  421 SQIIAYGITG KDRHTGAEQA LVVIQQITRN KVTLEPEFPP PITITLPYRD PINTIQLSHD 480
  481 AKYLTCSTAL ESRFLIISLQ KINEPRLIMK SVRSIDTSLE SEGITDTKLF PGNPNLMCIT 540
  541 STAFNSSPLV INTKITQING VRTVAQPSML IRVDEIGCKI HKCEISPRND AIAFLDRNGS 600
  601 VYIMCAPTMM DNNEKRRTIL VETVANAYRA YESATLRFNP EGNKLYILDR KGTFFVEDFA 660
  661 YGLPQSREIT KCKQIFHK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) PTR3 SSY1 SSY5

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #34 Asynchronous SPB prep Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..678] deduced N/A No confident structure predictions are available.
    2 View Details [147..219] deduced N/A No confident structure predictions are available.
    3 View Details [220..678] FFAS03 1.03 N-terminal (heme c) domain of cytochrome cd1-nitrite reductase; C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.51534322183238 bayes_pls_golite062009
  • protein binding
    		•  1.2335781397975 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  1.17860304426104 bayes_pls_golite062009
  • protein binding
    		•  0.0481598093678061 bayes_pls_golite062009
  • electron carrier activity
    		•  0.0445811956513282 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle