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Protein Overview: YER064C

General Information:
Name(s) found: YER064C [SGD]
Description(s) found:
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  • gi|731472|sp|P40041.1|YEP4_YEAST RecName: Full=Putative transcription factor YER064C [NCBI NR]
  • gi|6320907|ref|NP_010986.1| Non-essential nuclear protein; null mutation has global effects on transcription; Yer064cp [Saccharomyces cerevisiae] [NCBI NR]
  • gi|603300|gb|AAB64600.1| Yer064cp [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S50567 hypothetical protein YER064c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • Putative transcription factor YER064C OS=Saccharomyces cerevisiae GN=YER064C PE=1 SV=1 [Swiss-Prot]
  • Protein of unknown function localised to nucleus [mips]
  • Non-essential nuclear protein; null mutation has global effects on transcription [SGD]
  • YER064C, Chr V from 282703-284220, reverse complement [yeast_orfs2]
  • Chr V from 282703-284220, reverse complement [yeastorf3.fasta]
  • Chr V from 284220-282703, reverse complement [yeastorf5.fasta]
  • (P40041) Hypothetical 56.6 kDa protein in THO1-ICL1 intergenic region [4932.FASTACCERV.txt]
  • YER064C SGDID:S0000866, Chr V from 284220-282703, reverse complement, Uncharacterized ORF [yeastflysequest.fasta]
  • Non-essential nuclear protein; null mutation has global effects on transcription [Saccharomyces cerevisiae]gi|731472|sp|P40041|YEP4_YEAST Hypothetical 56.6 kDa protein in THO1-ICL1 intergenic regiongi|1077665|pir||S50567 hypothetical protein YER064c - y [nrdb_11152004_Chlamydomonas]
  • YER064C SGDID:S000000866, Chr V from 284220-282703, reverse complement, Uncharacterized ORF, "Non-essential nuclear protein; null mutation has global effects on transcription" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • Uncharacterized protein YER064C [nr-271106-contam.fasta]
  • Yer064cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Non-essential nuclear protein; null mutation has global effects on transcription; Yer064cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Putative transcription factor YER064C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YER064C PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • YER064C SGDID:S000000866, Chr V from 284222-282705, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Non-essential nuclear protein; null mutation has global effects on transcription" [yeast-030211-contam.fasta]
  • Transcription factor VHR2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VHR2 PE=1 SV=1 [YEAST.fasta.20131015]
  • VHR2 SGDID:S000000866, Chr V from 284222-282705, Genome Release 64-2-1, reverse complement, Verified ORF, "Non-essential nuclear protein; null mutation has global effects on transcription; VHR2 has a paralog, VHR1, that arose from the whole genome duplication; relative distribution to the nucleus increases upon DNA replication stress" [20141208_orf_trans.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 505 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: regulation of transcription [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIDDTENSKI HLEGSHKTGK YTGYGTTHKI RAQLNFNDEK KWKKFSSRRL ELIDSFGLSQ  60
   61 HKASEQDDNI RQIATILRSE FEYPDTFSAE FEKLVTAAVQ SVRRNRKRSK KKLLDSKKKI 120
  121 ARGKVQKIPL SPPSSSNMGS CSASNASSSD EEASVKEEPA EHALPSLNTI TSQKLLPYPN 180
  181 GRTLPPVPTQ VRSLLKKNAS LLRDPSAPYA HGGDEKLQKF DIEDQPLESE QEYDFIAKSI 240
  241 IVEIVNNAIP LPEQIQRDKF IRPNLTKKKG CQSKVVISNN LRKLILSKIH NSRTCLEMSK 300
  301 DERNLDSFAN LETLGKNSLM ASISLVVENS FSHLPSSTKQ YLTERLSSIE FLTILSQRLF 360
  361 MPATRQLFAD LSQEKIQVRV LNLILGSLVK DYGFDASLAP INEIIYHMTL HQYPLVCSNK 420
  421 QSNPMRPHST SEVLSAHSST KDASTPGKEE PRVTRSSTSA DSTIITLPSI EVPNTYDDDR 480
  481 LKMLSAISLQ IENSTFSKPF STISK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) AVO2 PMU1 YER064C YGL039W YTA12

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YER064C Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..211] deduced N/A No confident structure predictions are available.
    2 View Details [212..444] ORFEUS 7.57 RNase III endonuclease catalytic domain
    3 View Details [445..505] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • nucleic acid binding
    		•  3.56857846292068 bayes_pls_golite062009
  • binding
    		•  3.16671084167938 bayes_pls_golite062009
  • DNA binding
    		•  2.46976707655498 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.36798074064997 bayes_pls_golite062009
  • RNA binding
    		•  1.64815102811033 bayes_pls_golite062009
  • protein binding
    		•  1.33798788677218 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.28842676742386 bayes_pls_golite062009
  • transcription factor activity
    		•  1.27008996745235 bayes_pls_golite062009
  • structural molecule activity
    		•  1.15978347169403 bayes_pls_golite062009
  • double-stranded RNA binding
    		•  0.402046758389082 bayes_pls_golite062009
  • transcription activator activity
    		•  0.389298959802427 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.134687687018266 bayes_pls_golite062009
  • catalytic activity
    		•  0.00430305721638241 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle