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Protein Overview: CEM1

General Information:
Name(s) found: CEM1 / YER061C [SGD]
Description(s) found:
Found 11 descriptions.
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  • Mitochondrial beta-keto-acyl synthase with possible role in fatty acid synthesis; required for mitochondrial respiration [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 442 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article][TASLink to PubMed article]
    Biological Process: fatty acid biosynthetic process [ISSLink to PubMed article]
    Molecular Function: fatty acid synthase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRRVVITGL GCVTPLGRSL SESWGNLLSS KNGLTPITSL PNYNEDYKLR EKSIPSTITV  60
   61 GKIPENFQNE NSAINKLLFT SQDERRTSSF IKLALRTTYE ALHNAGLLNP NDITINTSLC 120
  121 NLDHFGCLIG SGIGSIQDIY QTSLQFHNDN KRINPYFVPK ILTNMAAGNV SIKFNLRGLS 180
  181 HSVSTACATG NNSIGDAFNF IRLGMQDICV AGASETSLHP LSLAGFIRAK SITTNGISRP 240
  241 FDTQRSGFVL GEGCGMIVME SLEHAQKRNA NIISELVGYG LSSDACHITS PPADGNGAKR 300
  301 AIEMALKMAR LEPTDVDYVN AHATSTLLGD KAECLAVASA LLPGRSKSKP LYISSNKGAI 360
  361 GHLLGARGAV ESIFTICSLK DDKMPHTLNL DNVLTLENNE ADKLHFIRDK PIVGANPKYA 420
  421 LCNSFGFGGV NTSLLFKKWE GS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data CEM1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..277]
    [357..376]    		 PSI-BLAST 825.0 Beta-ketoacyl-ACP synthase II
    2 View Details [278..356]
    [377..442]    		 PSI-BLAST 825.0 Beta-ketoacyl-ACP synthase II

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transferase activity, transferring acyl groups
    		•  4.09204107606289 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  3.79121338118181 bayes_pls_golite062009
  • 3-oxoacyl-[acyl-carrier-protein] synthase activity
    		•  3.71249191203055 bayes_pls_golite062009
  • C-acyltransferase activity
    		•  3.27532895419051 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  3.14957464437124 bayes_pls_golite062009
  • acyltransferase activity
    		•  3.06879684191353 bayes_pls_golite062009
  • transferase activity
    		•  2.15834234036431 bayes_pls_golite062009
  • catalytic activity
    		•  2.14505178497871 bayes_pls_golite062009
  • acetyl-CoA C-acyltransferase activity
    		•  2.06897329929762 bayes_pls_golite062009
  • acetyl-CoA C-acetyltransferase activity
    		•  1.50839304016514 bayes_pls_golite062009
  • C-acetyltransferase activity
    		•  1.19264084089277 bayes_pls_golite062009
  • holo-[acyl-carrier-protein] synthase activity
    		•  0.800737755066121 bayes_pls_golite062009
  • fatty-acyl-CoA synthase activity
    		•  0.696028474623411 bayes_pls_golite062009
  • transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
    		•  0.5334204157422 bayes_pls_golite062009
  • phosphotransferase activity, for other substituted phosphate groups
    		•  0.392307675469965 bayes_pls_golite062009
  • acetyltransferase activity
    		•  0.254850076259913 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle