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View Structure Prediction Details

Protein: CEM1
Organism: Saccharomyces cerevisiae
Length: 442 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CEM1.

Description E-value Query
Range
Subject
Range
gi|17131773, gi|... - gi|17230172|ref|NP_486720.1| polyketide synthase [Nostoc sp. PCC 7120], gi|17131773|dbj|BAB74379.1| ...
gi|25535295 - pir||AI2140 polyketide synthase [imported] - Nostoc sp. (strain PCC 7120)
0.0 [2..436] [27..447]
gi|29827480, gi|... - gi|29827480|ref|NP_822114.1| type I polyketide synthase AVES 2 [Streptomyces avermitilis MA-4680], g...
gi|5902892 - gi|5902892|dbj|BAA84475.1| type I polyketide synthase AVES 2 [Streptomyces avermitilis]
0.0 [1..440] [2678..3108]
gi|6007552 - gi|6007552|gb|AAF00959.1| McyD [Microcystis aeruginosa PCC 7806]
gi|6007552 - gi|6007552|gb|AAF00959.1|AF183408_7 McyD [Microcystis aeruginosa PCC 7806]
0.0 [2..438] [2119..2542]
gi|9955391 - gi|9955391|dbj|BAB12210.1| polyketide synthase [Microcystis aeruginosa]
0.0 [2..438] [2119..2542]

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Predicted Domain #1
Region A:
Residues: [1-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRRVVITGL GCVTPLGRSL SESWGNLLSS KNGLTPITSL PNYNEDYKLR EKSIPSTITV  60
   61 GKIPENFQNE NSAINKLLFT SQDERRTSSF IKLALRTTYE ALHNAGLLNP NDITINTSLC 120
  121 NLDHFGCLIG SGIGSIQDIY QTSLQFHNDN KRINPYFVPK ILTNMAAGNV SIKFNLRGLS 180
  181 HSVSTACATG NNSIGDAFNF IRLGMQDICV AGASETSLHP LSLAGFIRAK SITTNGISRP 240
  241 FDTQRSGFVL GEGCGMIVME SLEHAQKRNA NIISELV

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [357-376]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGAIGHLLGA RGAVESIFTI 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 825.0
Match: 1b3nA_
Description: Beta-ketoacyl-ACP synthase II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity, transferring acyl groups 4.09204107606289 bayes_pls_golite062009
fatty acid synthase activity 3.79121338118181 bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] synthase activity 3.71249191203055 bayes_pls_golite062009
C-acyltransferase activity 3.27532895419051 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.14957464437124 bayes_pls_golite062009
acyltransferase activity 3.06879684191353 bayes_pls_golite062009
transferase activity 2.15834234036431 bayes_pls_golite062009
catalytic activity 2.14505178497871 bayes_pls_golite062009
acetyl-CoA C-acyltransferase activity 2.06897329929762 bayes_pls_golite062009
acetyl-CoA C-acetyltransferase activity 1.50839304016514 bayes_pls_golite062009
C-acetyltransferase activity 1.19264084089277 bayes_pls_golite062009
holo-[acyl-carrier-protein] synthase activity 0.800737755066121 bayes_pls_golite062009
fatty-acyl-CoA synthase activity 0.696028474623411 bayes_pls_golite062009
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer 0.5334204157422 bayes_pls_golite062009
phosphotransferase activity, for other substituted phosphate groups 0.392307675469965 bayes_pls_golite062009
acetyltransferase activity 0.254850076259913 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [278-356]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYGLSSDACH ITSPPADGNG AKRAIEMALK MARLEPTDVD YVNAHATSTL LGDKAECLAV  60
   61 ASALLPGRSK SKPLYISSN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [377-442]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CSLKDDKMPH TLNLDNVLTL ENNEADKLHF IRDKPIVGAN PKYALCNSFG FGGVNTSLLF  60
   61 KKWEGS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 825.0
Match: 1b3nA_
Description: Beta-ketoacyl-ACP synthase II
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle