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Protein Overview: TIM9

General Information:
Name(s) found: TIM9 / YEL020W-A [SGD]
Description(s) found:
Found 26 descriptions.
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  • Essential protein of the mitochondrial intermembrane space, forms a complex with Tim10p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner membrane [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 87 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial intermembrane space [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    mitochondrial intermembrane space protein transporter complex [IDALink to PubMed article]
    Biological Process: protein import into mitochondrial inner membrane [IGILink to PubMed article][IPILink to PubMed articleLink to PubMed article][ISSLink to PubMed article]
    Molecular Function: protein transporter activity [IGILink to PubMed article][IPILink to PubMed article][ISSLink to PubMed article]
    unfolded protein binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDALNSKEQQ EFQKVVEQKQ MKDFMRLYSN LVERCFTDCV NDFTTSKLTN KEQTCIMKCS  60
   61 EKFLKHSERV GQRFQEQNAA LGQGLGR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) TIM10 TIM12 TIM22 TIM54 TIM9
    View Details Qiu et al. (2008) TIM10 TIM12 TIM13 TIM8 TIM9

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..87] PSI-BLAST 19.154902 Crystal structure of the TIM9 Tim10 hexameric complex


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle