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Protein Overview: APA2

General Information:
Name(s) found: APA2 / YDR530C [SGD]
Description(s) found:
Found 29 descriptions.
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  • Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase II (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 325 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: nucleotide metabolic process [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity [IDALink to PubMed article][IGILink to PubMed article][IMPLink to PubMed article]
    bis(5'-nucleosyl)-tetraphosphatase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIEENLKQKI HDKFVAAKKN GHLKVTHAES KKLKDPQTTT QYWVTFAPSL ALKPDANKNS  60
   61 DSKAEDPFAN PDEELVVTED LNGDGEYKLL LNKFPVVPEH SLLVTSEFKD QRSALTPSDL 120
  121 MTAYNVLCSL QGDKDDDVTC ERYLVFYNCG PHSGSSQDHK HLQIMQMPEK FIPFQDVLCN 180
  181 GKDHFLPTFN AEPLQDDKVS FAHFVLPLPE SSDQVDEDLL AMCYVSLMQR ALTFFQDWTN 240
  241 ESPELTKSYN VLLTKKWICV VPRSHAKSGP PLMLNINSTG YCGMILVKDR EKLENLTEDP 300
  301 HLVDKSLLQC GFPNTAGQKP TEYHY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data APA2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..325] ORFEUS 13.35 Galactose-1-phosphate uridylyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleic acid binding
    		•  1.74990165024183 bayes_pls_golite062009
  • binding
    		•  1.71599870633602 bayes_pls_golite062009
  • hydrolase activity
    		•  0.690968602046843 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.342529552808262 bayes_pls_golite062009
  • protein binding
    		•  0.315946879872005 bayes_pls_golite062009
  • catalytic activity
    		•  0.096119422680995 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle