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Protein Overview: UGO1

General Information:
Name(s) found: UGO1 / YDR470C [SGD]
Description(s) found:
Found 23 descriptions.
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  • Protein of unknown function; outer membrane component of the mitochondrial fusion machinery; Ugo1p bind directly to Fzo1p and Mgm1p and thereby link these two GTPases during mitochondrial fusion [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 502 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial outer membrane [IDALink to PubMed articleLink to PubMed article]
    Biological Process: filamentous growth [IMPLink to PubMed article]
    mitochondrial fusion [IGILink to PubMed article][IMPLink to PubMed articleLink to PubMed article][IPILink to PubMed article]
    transport [ISSLink to PubMed article]
    mitochondrial genome maintenance [IMPLink to PubMed article]
    Molecular Function: transporter activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNNNVTEAT SRAQIRPYYD PDSFNAGYSA VFKPDEGVVD PHGYTIASKL NVINSSPTTK  60
   61 RMANALFKSS PMKKLSNSVN DGLSLEGSNG EITGLNNFEW AELVNIQKWR KIFGQLLDMF 120
  121 FRKYFQLLIQ QPFDVARLLI QVGEFKIFKT TVDTNKPQAP IILRDEEGDG AAREGEEDAY 180
  181 DEEEIDFFPI ERKIAEANST APIMAEETDH SHHEPTDISL TIAPQSLHTI DVINALFDQE 240
  241 GIRGLWKANN TTFIYNFLSL SIDTWFTGLL SSFLGVPDPY FMEVINSPDI SKSFILALGA 300
  301 GVFTSIILLP VDLIRTRLIV TSFKKKKNVK TDGKNMVTNT RSLRQLIRCW SWRKNGVSIP 360
  361 LDMWSLTILQ SINNSFFNKL FDLVIYNQFH IEKYSQTVMY NTMKFFSKSL ELFIKLPLEN 420
  421 LLRRCQLNYL LNDQRLSFKV DSTELIVKPK KYNGIWDVIR NNSNTNRGQL WNGWKVGVIS 480
  481 LICGYGLQMM NKVDINMEQE KF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ECM3 UGO1 YML131W
    View Details Qiu et al. (2008) MON1 PUF2 UGO1 YDL133W YGR149W YOR292C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ASF1 3908: TAP-tagged, includes hir2(delta) in background Green EM, et al (2005)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..153] MSA 1.108992 View MSA. No confident structure predictions are available.
    2 View Details [154..502] PSI-BLAST 59.522879 structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle