Protein Overview: YDR306C

General Information:
Name(s) found:	YDR306C [SGD]
Description(s) found: Found 25 descriptions. SHOW ALL	F-box protein of unknown function; interacts with Sgt1p via a Leucine-Rich Repeat (LRR) domain [SGD]
Organism:	Saccharomyces cerevisiae
Length:	478 amino acids
Gene Ontology:
Cellular Component:	ubiquitin ligase complex [ISS]
Biological Process:	ubiquitin-dependent protein catabolic process [ISS]
Molecular Function:	protein binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANKSRPKKI KAPYRKYVAG EGFSSTRNDN KAKEFTITIP EDAELIETPQ GSYYYDETND  60
   61 TIVKLTRLSN EKKDKKGRKQ SPSSSSTSSS KGEKNGKVIE SEEARMHSVS VKMVLPWEIQ 120
  121 HRIIHYLDIP EKEEKLNKTA NGKKTTTGIN MNYLLVCRNW YAMCLPKLYY APALTSKNFN 180
  181 GFVDTIIINK KKNLGHYVFE LNLSTILQSG RNSFVSKLLR RCCSNLTKFI APQTSFGYAP 240
  241 LISLKSCHDL KFLDLGLVSE TVKLKELFSA IKNFTKLTHL SFPRSSIDCQ GFQDIQWPQN 300
  301 LRYLKLSGGI TNEFVIDTKW PTTITTLEFS YCPQITELSI YSLLSQIGDN LKHLFFHYPM 360
  361 PSLAENSLDH VFTYCANLIS LQLMVDYCSK WCFSEFMLSK LVEYDRPLKT LYLECSGSLG 420
  421 LASKIHPDDL TIAILESRLP CLKNICVSPK LGWNMKSDEV ADLVVSLEDQ DGSLYLNY

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		SPC2 YDR306C
View Details	Ho Y, et al. (2002)		CDC53 MDH1 PGM2 SAH1 SKP1 SRV2 STI1 YDR306C
View Details	Qiu et al. (2008)		HRT3 YDR306C

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	PRP42	YDR306C	1	Unpublished Fields Lab Data
View Screen	UBP6	YDR306C	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..478]	deduced	N/A	No confident structure predictions are available.
2	View Details	[94..478]	FFAS03	4.27	Skp2; Cyclin A/CDK2-associated p19, Skp2

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2