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Protein Overview: GYP7

General Information:
Name(s) found: GYP7 / YDL234C [SGD]
Description(s) found:
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  • gi|6319967|ref|NP_010047.1| GTPase-activating protein for yeast Rab family members including: Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking; Gyp7p [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S61057 GYP7 protein - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1431396|emb|CAA98814.1| GYP7 [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1346228|sp|P48365.1|GYP7_YEAST RecName: Full=GTPase-activating protein GYP7; AltName: Full=GAP for YPT7 [NCBI NR]
  • gi|1064935|emb|CAA56095.1| Gyp7p [Saccharomyces cerevisiae] [NCBI NR]
  • GTPase-activating protein GYP7 OS=Saccharomyces cerevisiae GN=GYP7 PE=1 SV=1 [Swiss-Prot]
  • GYP7 GTPase-activating protein for Ypt7p [mips]
  • GTPase-activating protein for yeast Rab family members including: Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking [SGD]
  • GYP7, Chr IV from 34238-36478, reverse complement [yeast_orfs2]
  • Chr IV from 34238-36478, reverse complement [yeastorf3.fasta]
  • Chr IV from 36478-34238, reverse complement [yeastorf5.fasta]
  • (P48365) GTPase-activating protein GYP7 (GAP for YPT7) [4932.FASTACCERV.txt]
  • GYP7 SGDID:S0002393, Chr IV from 36478-34238, reverse complement, Verified ORF [yeastflysequest.fasta]
  • GTPase-activating protein for yeast Rab family members including: Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking [Saccharomyces cerevisiae]gi|1431396|emb|CAA98814.1| GYP7 [Saccharomyces cere [nrdb_11152004_Chlamydomonas]
  • GYP7 SGDID:S000002393, Chr IV from 36478-34238, reverse complement, Verified ORF, "GTPase-activating protein for yeast Rab family members including: Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein traffic [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • GYP7 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Gyp7p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • GTPase-activating protein GYP7 (GAP for YPT7) [nr-271106-contam.fasta]
  • GTPase-activating protein for yeast Rab family members including: Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking; Gyp7p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • GYP7 SGDID:S000002393, Chr IV from 36478-34238, reverse complement, Verified ORF, "GTPase-activating protein for yeast Rab family members including: Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
  • GTPase-activating protein GYP7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GYP7 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • GYP7 SGDID:S000002393, Chr IV from 36477-34237, Genome Release 64-1-1, reverse complement, Verified ORF, "GTPase-activating protein for yeast Rab family members including: Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking" [yeast-030211-contam.fasta]
  • GYP7 SGDID:S000002393, Chr IV from 36477-34237, Genome Release 64-2-1, reverse complement, Verified ORF, "GTPase-activating protein for yeast Rab family members; members include Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking" [20141208_orf_trans.fasta]
  • YDL234C SGDID:S000002393, Chr IV from 36477-34237, Genome Release 64-1-1, reverse complement, Verified ORF, "GTPase-activating protein for yeast Rab family members including: Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 746 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: vesicle-mediated transport [IDALink to PubMed article]
    Molecular Function: Rab GTPase activator activity [IDALink to PubMed article][IMPLink to PubMed article][IPILink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKILFCKSK VFLHPTSDAR DNIAGFLLLT LEANKLSHQA ILQYIPESGL STLEISKLLK  60
   61 HEAKVGTCPT STPFVIENSI NFSNLVNTSL GQAFEISLSQ IYCIQFRPPS PNGWYVGSLV 120
  121 IYPLTEQFTG FQPPVLFFHD QLCPSTTDKL KRLRKSMNPF DDSDELYWGG VDLRNKINEL 180
  181 MELKKSNLEP EFWLVNPSLN DLRNFVSKDL LESYNNSKKD TTELATAGVK LNEKFQEWKW 240
  241 NVMSKIADVT TKSTNFIDSW LTNNSPIQKS QIDNEYLQKL LNNEKVKQIE QDYDSARVYL 300
  301 ANWSLGVKQE AERYQKQNKL FDSYRNNIFN DLNLTDELSD TEINNALQRQ FPLTEAKWNS 360
  361 LWDENDGRLR VTVNEVKDFI FHGGLENDSL RGKVWGFLLE IYPWDSSQDE RVQIDQTLAA 420
  421 EYDQLKLTWS KDFLQFDDED EEEYWNDQLF RISKDVRRCD RNLEIFQYNT IDGLPPPPQQ 480
  481 LPANENNSTS PESANDESDD ADDGVRNPHL IHLQNILITY NVYNTNLGYV QGMTDLLSPI 540
  541 YVIMKEEWKT FWCFTHFMDI MERNFLRDQS GIHEQMLTLV ELVQLMLPEL SEHLNKCDSG 600
  601 NLFFCFRMLL VWFKREFEME DIMHIWENFW TFYYSSQFQL FFMLAILQKN SQAILQHLNQ 660
  661 FDQILKFFNE LNGKLDWNDL MVRAELLFKK FEKMMHVMER DLQNVSSSSS SSSTGVLPCQ 720
  721 SERLTLLLSK KPIIRHEGQR SKNSVK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) GYP7 THS1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen IMP4 GYP7 2 Unpublished Fields Lab Data
    View Screen SOG2 GYP7 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data GYP7 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..250] MSA 2.051964 View MSA. No confident structure predictions are available.
    2 View Details [251..352] deduced N/A No confident structure predictions are available.
    3 View Details [353..570]
    [624..632]    		 PSI-BLAST 101.0103 Ypt/Rab-GAP domain of gyp1p
    4 View Details [571..623] PSI-BLAST 101.0103 Ypt/Rab-GAP domain of gyp1p
    5 View Details [633..746] MSA 2.177997 View MSA. Confident ab initio structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle