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Protein Overview: BUD23

General Information:
Name(s) found: BUD23 / YCR047C [SGD]
Description(s) found:
Found 33 descriptions.
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  • Methyltransferase, methylates residue G1575 of 18S rRNA; required for rRNA processing and nuclear export of 40S ribosomal subunits independently of methylation activity; diploid mutant displays random budding pattern [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 275 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: cellular bud site selection [IMPLink to PubMed article]
    Molecular Function: S-adenosylmethionine-dependent methyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRPEELAPP EIFYNDSEAH KYTGSTRVQH IQAKMTLRAL ELLNLQPCSF ILDIGCGSGL  60
   61 SGEILTQEGD HVWCGLDISP SMLATGLSRE LEGDLMLQDM GTGIPFRAGS FDAAISISAI 120
  121 QWLCNADTSY NDPKQRLMRF FNTLYAALKK GGKFVAQFYP KNDDQVDDIL QSAKVAGFSG 180
  181 GLVVDDPESK KNKKYYLVLS SGAPPQGEEQ VNLDGVTMDE ENVNLKKQLR QRLKGGKDKE 240
  241 SAKSFILRKK ELMKRRGRKV AKDSKFTGRK RRHRF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) BUD23 ECM16
    View Details Krogan NJ, et al. (2006) ASF2 BUD23 ECM16 REB1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data BUD23 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] PSI-BLAST 52.741366 Glycine N-methyltransferase
    2 View Details [203..275] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle