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Protein Overview: AGP1

General Information:
Name(s) found: AGP1 / YCL025C [SGD]
Description(s) found:
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  • gi|45644967|sp|P25376|AGP1_YEAST General amino acid permease AGP1 (Asparagine/glutamine permease) [NCBI NR]
  • gi|14588912|emb|CAA42360.2| asparagine and glutamine permease [Saccharomyces cerevisiae] [NCBI NR]
  • ref|NP_009905.2| Agp1p [Saccharomyces cerevisiae] [NCBI NR]
  • General amino acid permease AGP1 - Saccharomyces cerevisiae (Baker's yeast) [Swiss-Prot]
  • AGP1 Broad-specificity, relatively-low-affinity, amino-acid permease - inductible by most neutral amino acids [mips]
  • Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids; expression is regulated by the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p) [SGD]
  • AGP1, Chr III from 76131-77918, reverse complement [yeast_orfs2]
  • Chr III from 76131-77918, reverse complement [yeastorf3.fasta]
  • Chr III from 77918-76131, reverse complement [yeastorf5.fasta]
  • >CAA42360 (CAA42360) Asparagine and glutamine permease [4932.FASTACCERV.txt]
  • AGP1 SGDID:S0000530, Chr III from 77918-76131, reverse complement, Verified ORF [yeastflysequest.fasta]
  • Agp1p [Saccharomyces cerevisiae]gi|14588912|emb|CAA42360.2| asparagine and glutamine permease [Saccharomyces cerevisiae]gi|45644967|sp|P25376|AGP1_YEAST General amino acid permease AGP1 (Asparagine/glutamine permease) [nrdb_11152004_Chlamydomonas]
  • (P25376) General amino acid permease AGP1 (Asparagine/glutamine permease) [cerv4932.FASTAC]
  • AGP1 SGDID:S000000530, Chr III from 77918-76131, reverse complement, Verified ORF, "Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids; expression is regulated by the SPS plasma [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • General amino acid permease AGP1 (Asparagine/glutamine permease) [nr-271106-contam.fasta]
  • asparagine and glutamine permease [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 595 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [ISSLink to PubMed article]
    Biological Process: amino acid transport [IDALink to PubMed article]
    Molecular Function: epsilon hydroxylase activity [IGILink to PubMed article]
    amino acid transmembrane transporter activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSKSLYEL KDLKNSSTEI HATGQDNEIE YFETGSNDRP SSQPHLGYEQ HNTSAVRRFF  60
   61 DSFKRADQGP QDEVEATQMN DLTSAISPSS RQAQELEKNE SSDNIGANTG HKSDSLKKTI 120
  121 QPRHVLMIAL GTGIGTGLLV GNGTALVHAG PAGLLIGYAI MGSILYCIIQ ACGEMALVYS 180
  181 NLTGGYNAYP SFLVDDGFGF AVAWVYCLQW LCVCPLELVT ASMTIKYWTT SVNPDVFVII 240
  241 FYVLVITINI FGARGYAEAE FFFNCCKILM MTGFFILGII IDVGGAGNDG FIGGKYWHDP 300
  301 GAFNGKHAID RFKGVAATLV TAAFAFGGSE FIAITTAEQS NPRKAIPGAA KQMIYRILFL 360
  361 FLATIILLGF LVPYNSDQLL GSTGGGTKAS PYVIAVASHG VRVVPHFINA VILLSVLSMA 420
  421 NSSFYSSARL FLTLSEQGYA PKVFSYIDRA GRPLIAMGVS ALFAVIAFCA ASPKEEQVFT 480
  481 WLLAISGLSQ LFTWTAICLS HLRFRRAMKV QGRSLGELGF KSQTGVWGSA YACIMMILIL 540
  541 IAQFWVAIAP IGEGKLDAQA FFENYLAMPI LIALYVGYKV WHKDWKLFIR ETRST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen GPI14 AGP1 2 Hazbun TR, et al. (2003)
    View Screen GPI19 AGP1 1 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..87] deduced N/A No confident structure predictions are available.
    2 View Details [88..595] Pfam 202.769551 Amino acid permease No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.16072293434243 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.56123529621268 bayes_pls_golite062009
  • protein binding
    		•  1.36724461365736 bayes_pls_golite062009
  • tubulin binding
    		•  1.27811933320559 bayes_pls_golite062009
  • signal transducer activity
    		•  0.941563416769786 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.941563416769786 bayes_pls_golite062009
  • microtubule binding
    		•  0.433976380647151 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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    Created and Maintained by: Michael Riffle