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Protein Overview: REG2

General Information:
Name(s) found: REG2 / YBR050C [SGD]
Description(s) found:
Found 29 descriptions.
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  • Regulatory subunit of the Glc7p type-1 protein phosphatase; involved with Reg1p, Glc7p, and Snf1p in regulation of glucose-repressible genes, also involved in glucose-induced proteolysis of maltose permease [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 338 amino acids

    Gene Ontology:
    Cellular Component: protein phosphatase type 1 complex [IPILink to PubMed article]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter [IGILink to PubMed article]
    Molecular Function: protein phosphatase type 1 regulator activity [IGILink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLSNCDSLD NLFQDPPEEE ESSKFVEAVR TLMNRNDMGY PPAAANGTYC LKKIKSLNAK  60
   61 QWKINKKRMC MLPAVKKKNF DFHEQRSLIL NLNLWKFIKF INCSSKNNYN KNNKHVRSSN 120
  121 NTVKNENVLP LQKHKKVDND QRLENLFWRS WFKARKRRDI MGKPRERHIK FNDNVEQCII 180
  181 TDEHFIQRLP STRLNSTDEQ RPCSKSELDP CIGNAASKRS FYDYNSVYVA SDAIITTAAA 240
  241 TAIISSNSGD YQRGHDVRDV PRNVLLQAGE TDFSSVLRVD SDLKLSNISH HSPVKPSSTS 300
  301 SHSTFIFESE TDTDTDTDAE TENDIDAYID TSIPNLLL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) GAC1 GIP1 GIP2 PIG1 RCN1 REG1 REG2

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen REG2 POP2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..338] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle