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Protein Overview: BRN1

General Information:
Name(s) found: BRN1 / YBL097W [SGD]
Description(s) found:
Found 12 descriptions.
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  • Subunit of the condensin complex; required for chromosome condensation and for clustering of tRNA genes at the nucleolus; may influence multiple aspects of chromosome transmission [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 728 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nuclear condensin complex [IPILink to PubMed articleLink to PubMed article][ISSLink to PubMed articleLink to PubMed article][TASLink to PubMed article]
    Biological Process: mitotic chromosome condensation [IGILink to PubMed article][IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    mitotic sister chromatid segregation [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMANFEEWIK MATDNKINSR NSWNFALIDY FYDLDVLKDG ENNINFQKAS ATLDGCIKIY  60
   61 SSRVDSVTTE TGKLLSGLAQ RKTNGASNGD DSNGGNGEGL GGDSDEANIE IDPLTGMPIS 120
  121 NDPDVNNTRR RVYNRVLETT LVEFETIKMK ELDQELIIDP LFKKALVDFD EGGAKSLLLN 180
  181 TLNIDNTARV IFDASIKDTQ NVGQGKLQRK EEELIERDSL VDDENEPSQS LISTRNDSTV 240
  241 NDSVISAPSM EDEILSLGMD FIKFDQIAVC EISGSIEQLR NVVEDINQAK DFIENVNNRF 300
  301 DNFLTEEELQ AAVPDNAEDD SDGFDMGMQQ ELCYPDENHD NTSHDEQDDD NVNSTTGSIF 360
  361 EKDLMAYFDE NLNRNWRGRE HWKVRNFKKA NLVNKESDLL EETRTTIGDT TDKNTTDDKS 420
  421 MDTKKKHKQK KVLEIDFFKT DDSFEDKVFA SKGRTKIDMP IKNRKNDTHY LLPDDFHFST 480
  481 DRITRLFIKP AQKMSLFSHR KHTRGDVSSG LFEKSTVSAN HSNNDIPTIA DEHFWADNYE 540
  541 RKEQEEKEKE QSKEVGDVVG GALDNPFEDD MDGVDFNQAF EGTDDNEEAS VKLDLQDDED 600
  601 HKFPIRENKV TYSRVSKKVD VRRLKKNVWR SINNLIQEHD SRKNREQSSN DSETHTEDES 660
  661 TKELKFSDII QGISKMYSDD TLKDISTSFC FICLLHLANE HGLQITHTEN YNDLIVNYED 720
  721 LATTQAAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..118] MSA 1.010977 View MSA. No confident structure predictions are available.
    2 View Details [119..728] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle