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Protein Overview: AIM2

General Information:
Name(s) found: AIM2 / YAL049C [SGD]
Description(s) found:
Found 35 descriptions.
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  • Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 246 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASNQPGKCC FEGVCHDGTP KGRREEIFGL DTYAAGSTSP KEKVIVILTD VYGNKFNNVL  60
   61 LTADKFASAG YMVFVPDILF GDAISSDKPI DRDAWFQRHS PEVTKKIVDG FMKLLKLEYD 120
  121 PKFIGVVGYC FGAKFAVQHI SGDGGLANAA AIAHPSFVSI EEIEAIDSKK PILISAAEED 180
  181 HIFPANLRHL TEEKLKDNHA TYQLDLFSGV AHGFAARGDI SIPAVKYAKE KVLLDQIYWF 240
  241 NHFSNV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) AIM2 CDC33 TDA3 YDL025C YGR016W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data AIM2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..246] PSI-BLAST 26.221849 Dienelactone hydrolase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity
    		•  0.685577841077355 bayes_pls_golite062009
  • catalytic activity
    		•  0.629869101256762 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.116945164557932 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle