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Protein Overview: SPO7

General Information:
Name(s) found: SPO7 / YAL009W [SGD]
Description(s) found:
Found 30 descriptions.
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  • Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme, regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology, premeiotic replication, and sporulation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 259 amino acids

    Gene Ontology:
    Cellular Component: nuclear membrane-endoplasmic reticulum network [IDALink to PubMed article]
    integral to membrane [IDALink to PubMed article][ISSLink to PubMed article]
    Biological Process: ascospore formation [IMPLink to PubMed article]
    nucleus organization [IGILink to PubMed article][IMPLink to PubMed article]
    meiosis [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPESIGDVG NHAQDDSASI VSGPRRRSTS KTSSAKNIRN SSNISPASMI FRNLLILEDD  60
   61 LRRQAHEQKI LKWQFTLFLA SMAGVGAFTF YELYFTSDYV KGLHRVILQF TLSFISITVV 120
  121 LFHISGQYRR TIVIPRRFFT STNKGIRQFN VKLVKVQSTW DEKYTDSVRF VSRTIAYCNI 180
  181 YCLKKFLWLK DDNAIVKFWK SVTIQSQPRI GAVDVKLVLN PRAFSAEIRE GWEIYRDEFW 240
  241 AREGARRRKQ AHELRPKSE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) NEM1 SPO7

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SPO7 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..259] Pfam 184.79588 Spo7-like protein No confident structure predictions are available.
    2 View Details [161..259] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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