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Protein Overview: CG10956-PB

General Information:
Name(s) found: CG10956-PB / FBpp0110074 [FlyBase]
Description(s) found:
Found 17 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG10956 (CG10956, FBgn0034195). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13010398..13011742. It has the cytological map location 53F12. Based on sequence similarity, it is predicted to have molecular function</span>: serine-type endopeptidase inhibitor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: negative regulation of proteolysis. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 379 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: negative regulation of proteolysis [ISS]
    Molecular Function: serine-type endopeptidase inhibitor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYVLLLILLG ISRYRAQKNS QLPDELYAAI VNSFSNRNIM FSTEMIRSSM LFIYVGVEED  60
   61 ESEQIRKAMH YRGTHLSEYK PKTQKIFAMS VKKAPVAKSL TRFYVRQNMK MSTEYRVFMR 120
  121 HTEGRARNIA FAREQLDEVN TFYSHEMGEQ IGQVVKESWW KPNSQGLLVN AIFFNLSWER 180
  181 TFNPEATYPR EFRVNATKSV MIPMMHEDSK FAFGILGNLK ATAVLVPFSH GDLRMLLIKP 240
  241 DQPDGLAALQ MKLQAMNILS VARNLTMMDV FVGIPKFKIH SDLELSPAFE KMGIKDIFKP 300
  301 SKSFSTLLHR NTNFRIDGVI HVVTFEFQEQ GIGTPSTDVG NGSLTHTFNG VKYFLATHPF 360
  361 AFYIIDNTSI YFAGHVTSF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..379] PSI-BLAST 90.221849 No description for 2gd4I was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • serine-type endopeptidase inhibitor activity
    		•  6.13717785773502 bayes_pls_golite062009
  • peptidase inhibitor activity
    		•  6.07523919900796 bayes_pls_golite062009
  • endopeptidase inhibitor activity
    		•  6.01194624525726 bayes_pls_golite062009
  • enzyme inhibitor activity
    		•  3.67290572457064 bayes_pls_golite062009
  • protease binding
    		•  2.69747551802498 bayes_pls_golite062009
  • enzyme regulator activity
    		•  2.47388770421699 bayes_pls_golite062009
  • binding
    		•  2.02049891212041 bayes_pls_golite062009
  • protein binding
    		•  1.90236643189719 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  1.61358221181146 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.46959492426289 bayes_pls_golite062009
  • DNA binding
    		•  1.31854786197421 bayes_pls_golite062009
  • transporter activity
    		•  1.29851101299849 bayes_pls_golite062009
  • heparin binding
    		•  1.21540270241849 bayes_pls_golite062009
  • receptor activity
    		•  1.1966923866485 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.14424818451335 bayes_pls_golite062009
  • signal transducer activity
    		•  1.12659599250323 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.12659599250323 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.07876412297114 bayes_pls_golite062009
  • receptor binding
    		•  1.0390886965673 bayes_pls_golite062009
  • polysaccharide binding
    		•  0.99559313679422 bayes_pls_golite062009
  • type 2 angiotensin receptor binding
    		•  0.92552398196189 bayes_pls_golite062009
  • collagen binding
    		•  0.307023895861541 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.262958899612658 bayes_pls_golite062009
  • growth factor activity
    		•  0.21183671094477 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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