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Protein Overview: stmA-PC

General Information:
Name(s) found: stmA-PC / FBpp0100147 [FlyBase]
Description(s) found:
Found 16 descriptions.
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  • The gene stambha A is referred to in FlyBase by the symbol Dmel\stmA (CG8739, FBgn0086784). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4617003..4621809. It has the cytological map location 44E3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. There is experimental evidence that it is involved in the biological process</span>: synaptic transmission; phototransduction; cytokinesis; synaptic vesicle exocytosis. 49 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system; nervous system; adult segment; peripheral nervous system; adult mesothoracic segment; extended germ band embryo; portion of tissue; embryonic nervous system; embryonic hindgut; cytoplasmic part; adult brain; presynaptic active zone membrane; terminal button; primordium; external compound sense organ; late extended germ band embryo. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 834 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [NAS]
    integral to membrane of membrane fraction [IDA]
    Biological Process: cytokinesis [IMP]
    synaptic transmission [IMP]
    synaptic vesicle exocytosis [IMP]
    phototransduction [IMP]
    Molecular Function: binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALIRCCFEP PELPEFFDSF VQKCTDPSCC CGCCSALRPR YKRLVDNIFP VNPEDGLVKS  60
   61 NMEKLTFYSL SSPDKLDRIG EYLYQKATKD INRKRYKLAE IAMEAMDLLL QACHAQTTLN 120
  121 LFVESFLRMV QKLLEDSNPN LKIMATNSFV KFANINEDTP SYHRRYDFFI SKFSSMCHSD 180
  181 AASMRDSLRL AGIKGLQGVI RKTVSDDLVE NIWEAEHMEK IVPSLLFNMQ FCVNVMFVKK 240
  241 NLLASGDLTP VEDATNVTPP ALAEEVLREL VGRASFGHIR SVLKPLLTHL DRHELWVPNT 300
  301 FAIHTFRIVM ISIQPQYSYT VVETLMQHLD NNFKSSPKTR TSLAVVLSKI IAIAAGESVG 360
  361 PSALDIINNL LTHLRTSVST TSEITPEESQ YQEALINALG EFANHHPDYQ KIEIMLFIMN 420
  421 TVPDLSKKSK GDQMLQNILL KSLLKVGTQY STVSFEKAFP ASFLQPLLKM ARAPHNPTRM 480
  481 VVMQILQALL DRHQNEQVLS SVSVKPYPAL SQEPPSRSDI IFTHKYGANI MQALIDSMAL 540
  541 SDRVDALTSS FNTAALLIVE MSCNETVQEF LLFILGIQQV ACTVDTLGNV HKCSLHAISI 600
  601 GLLVLISRVS GINNLLEYAQ KIVDARREEA SHFLPPLLEP KKLAGKTFNL QLPHLAIDKL 660
  661 ALGECLQNAG MDAQRLNTGA PYSLNQTDHP GHRHSWVESV SNQLTQRNSS ADLTVYNGDV 720
  721 DSVSSSPGVC KKLLAPEFNF DAMKRALAEP TEAAKREQRE RQMQIVRTFR EGEFDDLMRR 780
  781 TEPKHDLIQN RLNELFNSLA VERQITQSDT KSSQLQASNE KPIYETNFPE LFYY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..136] FFAS03 1.01 Mouse Importin alpha- phosphorylated SV40 CN peptide complex
    2 View Details [137..834] FFAS03 1.37 No description for 2ie3A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transporter activity
    		•  2.3766833486706 bayes_pls_golite062009
  • binding
    		•  2.33303322187387 bayes_pls_golite062009
  • protein transporter activity
    		•  2.05261715803466 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.87445049214426 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  1.66484599039895 bayes_pls_golite062009
  • protein binding
    		•  1.5114863464349 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.2724388835449 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.15714523804341 bayes_pls_golite062009
  • signal transducer activity
    		•  0.892292340575145 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.892292340575145 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.80477645195818 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  0.262911024668873 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.260663498540354 bayes_pls_golite062009
  • clathrin binding
    		•  0.116858812089923 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.0909907234708774 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.0128158555898987 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.00672548245940896 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle