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Protein Overview: CG11360-PA, FBpp...

General Information:
Name(s) found: FBpp0302678 [FlyBase]
FBpp0302677 [FlyBase]
FBpp0302676 [FlyBase]
CG11360-PA / FBpp0088160 [FlyBase]
Description(s) found:
Found 35 descriptions.
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  • type=protein; loc=4:join(701335..701761,705207..706666); ID=FBpp0302678; name=CG11360-PE; parent=FBgn0039920,FBtr0310541; dbxref=REFSEQ:NP_001259070,GB_protein:AGB96560,FlyBase:FBpp0302678,FlyBase_Annotation_IDs:CG11360-PE; MD5=cb4a185854f457ecaed1f0a0e0237ed4; length=628; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=4:join(701335..701761,705207..706666); ID=FBpp0302677; name=CG11360-PD; parent=FBgn0039920,FBtr0310540; dbxref=REFSEQ:NP_001259069,GB_protein:AGB96559,FlyBase:FBpp0302677,FlyBase_Annotation_IDs:CG11360-PD; MD5=cb4a185854f457ecaed1f0a0e0237ed4; length=628; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=4:join(701335..701761,705207..706666); ID=FBpp0302676; name=CG11360-PC; parent=FBgn0039920,FBtr0310539; dbxref=REFSEQ:NP_001259068,GB_protein:AGB96558,FlyBase:FBpp0302676,FlyBase_Annotation_IDs:CG11360-PC; MD5=cb4a185854f457ecaed1f0a0e0237ed4; length=628; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG11360 (CG11360, FBgn0039920). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:701245..706796. It has the cytological map location 102D4. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: RNA binding; protein binding; zinc ion binding. There is experimental evidence that it is involved in the biological process</span>: regulation of alternative nuclear mRNA splicing, via spliceosome. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 628 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IC]
    Biological Process: regulation of alternative nuclear mRNA splicing, via spliceosome [IMP]
    Molecular Function: zinc ion binding [IEA]
    protein binding [IEA]
    RNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAQVTPKIS TCINSKGSIQ KKNQAQHHDM SEQSKVNEST LPLSDDPRTL QLALELSLVG  60
   61 FNDNQNCYAQ PAQPLPMPLS ARSDFEIGTI NSTLPIPSAP NCLLLPNAGA VSSEDRSKKS 120
  121 QNMTECVPVP SSEHVAEIVG RQGCKIKALR AKTNTYIKTP VRGEEPVFVV TGRKEDVNKA 180
  181 KREILSAADH FSLIRASRKP VSDSQNNGMV GSTTSSGGGA VPRMSGPPCM PGQVTIQVRV 240
  241 PYRVVGLVVG PKGATIKHIQ QETQTYIVTP SREKEPIFEV TGLPDNVDTA RKQIEAHIAL 300
  301 RTGSGSGSGD AITMQSSDSV DTKEYASLPS LTQILNDDLN SEILSSIYKN SVPSTQEYAN 360
  361 NSMKTVVNVS NSVKLVQGHH TGNCFQKSEF AEMEMTANIT AADILDKRLP GNEVSVPLAK 420
  421 ANVANIVFRT TSSKTLSFCP PTSTSASFHS NCNANILTRS CSSASSTTST KSTNNSANTP 480
  481 PEILNIWKSI SDSIDVDEGI GDSPSIWNQP ANIIPTAHCS PTISISPTDS LLGMGEHSAN 540
  541 QQNLNHAKEP IMPNLPQKIK GIQVQSNADN FLTHRECFVC NENTVTTALV PCGHNMFCME 600
  601 CANHICLSMD AVCPVCNSIV YHAMRILG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] PSI-BLAST 3.69897 Structural genomics, 1.5A crystal structure of a hypothetical protein APE0754 from Aeropyrum pernix
    2 View Details [203..303] PSI-BLAST 8.30103 No description for 2dgrA was found.
    3 View Details [304..385] deduced N/A No confident structure predictions are available.
    4 View Details [386..628] PSI-BLAST 11.30103 Cbl; N-terminal domain of cbl (N-cbl); CBL

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  5.18414740305744 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.78650555542715 bayes_pls_golite062009
  • mRNA binding
    		•  3.82977088614136 bayes_pls_golite062009
  • binding
    		•  3.45962790790935 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.28364833275102 bayes_pls_golite062009
  • DNA binding
    		•  2.03207983673692 bayes_pls_golite062009
  • transcription factor activity
    		•  1.30278154718684 bayes_pls_golite062009
  • protein binding
    		•  1.16541072642796 bayes_pls_golite062009
    		• 1.02980840568405 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  0.63404501189528 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.489176583045793 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.392035003865213 bayes_pls_golite062009
  • transcription activator activity
    		•  0.324382863054631 bayes_pls_golite062009
  • transcription factor binding
    		•  0.254024117548226 bayes_pls_golite062009
  • catalytic activity
    		•  0.113112541746059 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.0321875054165348 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  3.12724619324809 bayes_pls_golite062009
  • protein binding
    		•  2.14586566310919 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.09146786953566 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.06449122804353 bayes_pls_golite062009
  • DNA binding
    		•  1.74278466000445 bayes_pls_golite062009
  • transcription factor activity
    		•  1.29826570244834 bayes_pls_golite062009
  • molecular adaptor activity
    		•  0.494024302340603 bayes_pls_golite062009
  • SH3/SH2 adaptor activity
    		•  0.409062479526042 bayes_pls_golite062009
  • protein binding, bridging
    		•  0.370788151516215 bayes_pls_golite062009
  • signal transducer activity
    		•  0.150891693412241 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.150891693412241 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle