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View Structure Prediction Details

Protein: CG11360-PA, FBpp...
Organism: Drosophila melanogaster
Length: 628 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG11360-PA, FBpp....

Description E-value Query
Range
Subject
Range
gi|66771361 - gi|66771361|gb|AAY54992.1| IP11918p [Drosophila melanogaster]
278.0 [0..1] [628..30]

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Predicted Domain #1
Region A:
Residues: [1-202]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAQVTPKIS TCINSKGSIQ KKNQAQHHDM SEQSKVNEST LPLSDDPRTL QLALELSLVG  60
   61 FNDNQNCYAQ PAQPLPMPLS ARSDFEIGTI NSTLPIPSAP NCLLLPNAGA VSSEDRSKKS 120
  121 QNMTECVPVP SSEHVAEIVG RQGCKIKALR AKTNTYIKTP VRGEEPVFVV TGRKEDVNKA 180
  181 KREILSAADH FSLIRASRKP VS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 1tuaA
Description: Structural genomics, 1.5A crystal structure of a hypothetical protein APE0754 from Aeropyrum pernix
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 5.18414740305744 bayes_pls_golite062009
nucleic acid binding 4.78650555542715 bayes_pls_golite062009
mRNA binding 3.82977088614136 bayes_pls_golite062009
binding 3.45962790790935 bayes_pls_golite062009
transcription regulator activity 2.28364833275102 bayes_pls_golite062009
DNA binding 2.03207983673692 bayes_pls_golite062009
transcription factor activity 1.30278154718684 bayes_pls_golite062009
protein binding 1.16541072642796 bayes_pls_golite062009
1.02980840568405 bayes_pls_golite062009
poly-pyrimidine tract binding 0.63404501189528 bayes_pls_golite062009
mRNA 3'-UTR binding 0.489176583045793 bayes_pls_golite062009
transcription repressor activity 0.392035003865213 bayes_pls_golite062009
transcription activator activity 0.324382863054631 bayes_pls_golite062009
transcription factor binding 0.254024117548226 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009
sequence-specific DNA binding 0.0321875054165348 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [203-303]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSQNNGMVGS TTSSGGGAVP RMSGPPCMPG QVTIQVRVPY RVVGLVVGPK GATIKHIQQE  60
   61 TQTYIVTPSR EKEPIFEVTG LPDNVDTARK QIEAHIALRT G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.30103
Match: 2dgrA
Description: No description for 2dgrA was found.

Predicted Domain #3
Region A:
Residues: [304-385]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGSGSGDAIT MQSSDSVDTK EYASLPSLTQ ILNDDLNSEI LSSIYKNSVP STQEYANNSM  60
   61 KTVVNVSNSV KLVQGHHTGN CF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [386-628]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKSEFAEMEM TANITAADIL DKRLPGNEVS VPLAKANVAN IVFRTTSSKT LSFCPPTSTS  60
   61 ASFHSNCNAN ILTRSCSSAS STTSTKSTNN SANTPPEILN IWKSISDSID VDEGIGDSPS 120
  121 IWNQPANIIP TAHCSPTISI SPTDSLLGMG EHSANQQNLN HAKEPIMPNL PQKIKGIQVQ 180
  181 SNADNFLTHR ECFVCNENTV TTALVPCGHN MFCMECANHI CLSMDAVCPV CNSIVYHAMR 240
  241 ILG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.30103
Match: 1fbvA
Description: Cbl; N-terminal domain of cbl (N-cbl); CBL
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 3.12724619324809 bayes_pls_golite062009
protein binding 2.14586566310919 bayes_pls_golite062009
nucleic acid binding 2.09146786953566 bayes_pls_golite062009
transcription regulator activity 2.06449122804353 bayes_pls_golite062009
DNA binding 1.74278466000445 bayes_pls_golite062009
transcription factor activity 1.29826570244834 bayes_pls_golite062009
molecular adaptor activity 0.494024302340603 bayes_pls_golite062009
SH3/SH2 adaptor activity 0.409062479526042 bayes_pls_golite062009
protein binding, bridging 0.370788151516215 bayes_pls_golite062009
signal transducer activity 0.150891693412241 bayes_pls_golite062009
molecular transducer activity 0.150891693412241 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle