Protein Overview: DNM1

General Information:
Name(s) found:	DNM1 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|59853099\|ref\|NP_004399.2\| dynamin 1 isoform 1 [Homo sapiens] [NCBI NR] gi\|55961114\|emb\|CAI13837.1\| dynamin 1 [Homo sapiens] [NCBI NR] gi\|172046078\|sp\|Q05193.2\|DYN1_HUMAN RecName: Full=Dynamin-1 [NCBI NR] dynamin 1 [HGNC (HUGO)] Dynamin-1 OS=Homo sapiens GN=DNM1 PE=1 SV=2 [Swiss-Prot] Tax_Id=9606 dynamin 1 isoform 1 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] dynamin 1 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] Tax_Id=9606 Dynamin 1 [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta] Dynamin-1 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] dynamin 1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] RecName: Full=Dynamin-1 [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=DNM1 Isoform 1 of Dynamin-1 [human-ipi-250309-contam.fasta] IPI:IPI00413140.4\|SWISS-PROT:Q05193-1\|ENSEMBL:ENSP00000362014\|REFSEQ:NP_004399\|VEGA:OTTHUMP00000022236 Tax_Id=9606 Gene_Symbol=DNM1 Isoform 1 of Dynamin-1 [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=DNM1 dynamin 1 isoform 1 [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta] dynamin-1 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Q05193;A6NLM6;Q5SYX0;Q5SYX2;Q6P3T6;Q86VD2; RecName: Full=Dynamin-1; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Isoform 1 of Dynamin-1 OS=Homo sapiens GN=DNM1 [011711_HMR.fasta] GeneSymbol=DNM1 Synonyms=DNM dynamin-1 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] Dynamin-1 GN=DNM1 [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	864 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNRGMEDLI PLVNRLQDAF SAIGQNADLD LPQIAVVGGQ SAGKSSVLEN FVGRDFLPRG  60
   61 SGIVTRRPLV LQLVNATTEY AEFLHCKGKK FTDFEEVRLE IEAETDRVTG TNKGISPVPI 120
  121 NLRVYSPHVL NLTLVDLPGM TKVPVGDQPP DIEFQIRDML MQFVTKENCL ILAVSPANSD 180
  181 LANSDALKVA KEVDPQGQRT IGVITKLDLM DEGTDARDVL ENKLLPLRRG YIGVVNRSQK 240
  241 DIDGKKDITA ALAAERKFFL SHPSYRHLAD RMGTPYLQKV LNQQLTNHIR DTLPGLRNKL 300
  301 QSQLLSIEKE VEEYKNFRPD DPARKTKALL QMVQQFAVDF EKRIEGSGDQ IDTYELSGGA 360
  361 RINRIFHERF PFELVKMEFD EKELRREISY AIKNIHGIRT GLFTPDMAFE TIVKKQVKKI 420
  421 REPCLKCVDM VISELISTVR QCTKKLQQYP RLREEMERIV TTHIREREGR TKEQVMLLID 480
  481 IELAYMNTNH EDFIGFANAQ QRSNQMNKKK TSGNQDEILV IRKGWLTINN IGIMKGGSKE 540
  541 YWFVLTAENL SWYKDDEEKE KKYMLSVDNL KLRDVEKGFM SSKHIFALFN TEQRNVYKDY 600
  601 RQLELACETQ EEVDSWKASF LRAGVYPERV GDKEKASETE ENGSDSFMHS MDPQLERQVE 660
  661 TIRNLVDSYM AIVNKTVRDL MPKTIMHLMI NNTKEFIFSE LLANLYSCGD QNTLMEESAE 720
  721 QAQRRDEMLR MYHALKEALS IIGDINTTTV STPMPPPVDD SWLQVQSVPA GRRSPTSSPT 780
  781 PQRRAPAVPP ARPGSRGPAP GPPPAGSALG GAPPVPSRPG ASPDPFGPPP QVPSRPNRAP 840
  841 PGVPSRSGQA SPSRPESPRP PFDL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
actin binding	3.72754591832642	bayes_pls_golite062009
cytoskeletal protein binding	3.48744511411671	bayes_pls_golite062009
binding	3.29080729281876	bayes_pls_golite062009
protein binding	3.17213698546013	bayes_pls_golite062009
transcription regulator activity	2.10584700564436	bayes_pls_golite062009
actin filament binding	2.03444575838575	bayes_pls_golite062009
DNA binding	1.77960272183811	bayes_pls_golite062009
glutamate receptor binding	1.76346239890943	bayes_pls_golite062009
molecular transducer activity	1.55319485371003	bayes_pls_golite062009
signal transducer activity	1.55319485371003	bayes_pls_golite062009
nucleic acid binding	1.55295906221034	bayes_pls_golite062009
clathrin binding	1.29927347270153	bayes_pls_golite062009
transporter activity	1.28986800087234	bayes_pls_golite062009
phospholipid binding	1.09683218092034	bayes_pls_golite062009
receptor binding	1.00859318603128	bayes_pls_golite062009
protein domain specific binding	0.90578029954417	bayes_pls_golite062009
substrate-specific transporter activity	0.79883446648737	bayes_pls_golite062009
phosphoinositide binding	0.71817045430443	bayes_pls_golite062009
profilin binding	0.66906205737225	bayes_pls_golite062009
structural constituent of cytoskeleton	0.35466574267734	bayes_pls_golite062009
receptor activity	0.353510125274044	bayes_pls_golite062009
beta-amyloid binding	0.34714857141225	bayes_pls_golite062009
transmembrane receptor activity	0.207829786337892	bayes_pls_golite062009
structural molecule activity	0.160152014803717	bayes_pls_golite062009
protein complex binding	0.15504114076075	bayes_pls_golite062009
alpha-catenin binding	0.102004310679969	bayes_pls_golite062009
receptor signaling protein activity	0.10105990547756	bayes_pls_golite062009
pyrophosphatase activity	0.0611639610381174	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.0524559849408587	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.0498422520006935	bayes_pls_golite062009

No functions predicted.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..318]	PSI-BLAST	136.0	Structure of the nucleotide-free myosin II motor domain from Dictyostelium discoideum fused to the GTPase domain of dynamin 1 from Rattus norvegicus
2	View Details	[319..512]	MSA	1.22296	View MSA. No confident structure predictions are available.
3	View Details	[513..631]	PSI-BLAST	30.39794	Dynamin
4	View Details	[632..744]	Pfam	28.769551	No description for PF02212.9 was found. Confident ab initio structure predictions are available.
5	View Details	[745..864]	PSI-BLAST	3.522879	No description for 1y0fA was found.

Protein Overview: DNM1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: