YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: chn-PC

General Information:
Name(s) found: chn-PC / FBpp0110305 [FlyBase]
Description(s) found:
Found 19 descriptions.
SHOW ALL
  • The gene charlatan is referred to in FlyBase by the symbol Dmel\chn (CG11798, FBgn0015371). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11002762..11032288. It has the cytological map location 51E1-51E2. There is experimental evidence that it has the molecular function</span>: protein binding; sequence-specific DNA binding; RNA polymerase II transcription factor activity, enhancer binding; specific transcriptional repressor activity. There is experimental evidence that it is involved in the biological process</span>: progression of morphogenetic furrow during compound eye morphogenesis; eye development; positive regulation of transcription from RNA polymerase II promoter; sensory organ development; embryonic development via the syncytial blastoderm; negative regulation of compound eye cone cell fate specification; peripheral nervous system development. 40 alleles are reported. The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: adult segment; peripheral nervous system; adult mesothoracic segment; nervous system; embryonic nervous system; external compound sense organ; postalar bristle; embryonic peripheral nervous system; morphogenetic furrow; embryonic heart; organ system subdivision; dorsal thoracic disc. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1214 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IC]
    intracellular [IEA]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter [NAS]
    eye development [IMP]
    embryonic development via the syncytial blastoderm [IMP]
    nervous system development [NAS]
    peripheral nervous system development [IMP]
    negative regulation of compound eye cone cell fate specification [IMP]
    positive regulation of transcription from RNA polymerase II promoter [IMP]
    progression of morphogenetic furrow during compound eye morphogenesis [IMP]
    sensory organ development [IMP]
    Molecular Function: transcription factor activity [ISS][NAS]
    zinc ion binding [IEA]
    protein binding [IPI]
    RNA polymerase II transcription factor activity, enhancer binding [IDA]
    sequence-specific DNA binding [IDA]
    specific transcriptional repressor activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATLIPVNGG HPAASGQSSN VEATYEDMFK EITRKLYGEE TGNGLHTLGT PVAQVATSGP  60
   61 TAVPEGEQRS FTNLQQLDRS AAPSIEYESS AAGASGNNVA TTQANVIQQQ QQQQQQAESG 120
  121 NSVVVTASSG ATVVPAPSVA AVGGFKSEDH LSTAFGLAAL MQNGFAAGQA GLLKAGEQQQ 180
  181 RWAQDGSGLV AAAAAEPQLV QWTSGGKLQS YAHVNQQQQQ QQQPHQSTPK SKKHRQEHAA 240
  241 ELIYASPSTS ANAAQNLAQS TPTSAPSNSS GGSTSSSGGG GGRKKAAQAA AAAAAANGVH 300
  301 IQKRYACTHC PYSTDRRDLY TRHENIHKDE KPFQCYACLK QFNRADHVKK HFLRMHRELQ 360
  361 YDINKTRRHV SAGSGSSGSG SSGSGSHHSG GRGNVTINSA GVNIDNAFLE AQRHPTSSSM 420
  421 SIVETIEAVA SATDMPLAQL KQEKMDDGAG VVLPLHVGVM QQPVASSSSG SSGSHGGNGN 480
  481 GGSGSGLLKP KREKRFTCCY CPWSGADKWG LKRHLNTHTK PFVCLLCDYK AARSERLATH 540
  541 VLKVHNKRAC SKCSYLADTQ EEYQAHMSDV HGNVGNANGG GGAVTIYTTT TNEGVAGGGG 600
  601 GGGGGISGNI SGGGPLQEII VNPSSMVGWR LSANGSLIPP HDLLTGGLPN AATQKRGSER 660
  661 LFQYLEAEGS DPEDYARLLK MDAISRNTAS VAQDFHKAGG VHELKIPANH QLLFNNKLPS 720
  721 QWTTREAAAL LYSLSNMGGG SASSVSGSQR QKFGMRARQH STGEDDENTP SSASSSSFSG 780
  781 DEFNMSATSP LKLSRHAIKL EKMDEMDAKD MGPTKAMMAT AFLEAANYEQ TAIELLASKR 840
  841 KIKVENDNDE DQENQQHQPH QQHHSQQQQQ QRLQLIKSSP AYKLNNNNNN NSNNNNYYKD 900
  901 KTSHRNAVHH HRQDDKENNK TKSPGTAAVS VAAAAATSPP SISGPSNQTP FLTQMEYQNL 960
  961 NRIGTQFQNY VKDIINKYYA AETPLMLAAA AAALPTATTT GQQQQPELDI ENLSPSKRRR1020
 1021 LLSETEEYIE YLRNKEDITL TIAPKVQPPA PVTSLLKRQL DLSTPRRSPK KAAPAHSNSA1080
 1081 SNASRKSLNQ LATLLPLLAD AASQQEYLAA PLDFSKKSSS RKQAQPKKIR LTPEAVVTLL1140
 1141 RDKYLNRMVR QRLGCLKCNQ LRKNSSISFN YHTLGSLALH KYWRHGRLGS SSTRREKLQA1200
 1201 ALQKRISRGQ ADKC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..145] MSA 2.434989 View MSA. No confident structure predictions are available.
    2 View Details [146..384] PSI-BLAST 48.522879 No description for 2i13A was found.
    3 View Details [385..462] PSI-BLAST 16.0 Five-finger GLI1
    4 View Details [463..610] PSI-BLAST 17.0 Transcription factor IIIA, TFIIIA
    5 View Details [611..676] PSI-BLAST 3.69897 HIGH-RESOLUTION SOLUTION STRUCTURE OF THE DOUBLE CYS2*HIS2 ZINC FINGER FROM THE HUMAN ENHANCER BINDING PROTEIN MBP-1
    6 View Details [677..760] deduced N/A No confident structure predictions are available.
    7 View Details [761..949] deduced N/A No confident structure predictions are available.
    8 View Details [950..1077] deduced N/A No confident structure predictions are available.
    9 View Details [1078..1214] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • transcription regulator activity
    		•  4.70988788192472 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.58713908116892 bayes_pls_golite062009
  • DNA binding
    		•  4.56219307357342 bayes_pls_golite062009
  • transcription activator activity
    		•  3.52873291636993 bayes_pls_golite062009
  • transcription factor activity
    		•  3.50954949535763 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.27542149084008 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.22082323675675 bayes_pls_golite062009
  • binding
    		•  3.10743787485868 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.53101891154822 bayes_pls_golite062009
  • chromatin binding
    		•  2.18464662431232 bayes_pls_golite062009
  • protein binding
    		•  2.05530362750351 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.63161912031789 bayes_pls_golite062009
  • transcription factor binding
    		•  1.39608963544799 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.34049786451995 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.77874411480713 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009
    5
    Term Confidence Notes
  • transcription regulator activity
    		•  4.70988788192472 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.58713908116892 bayes_pls_golite062009
  • DNA binding
    		•  4.56219307357342 bayes_pls_golite062009
  • transcription activator activity
    		•  3.52873291636993 bayes_pls_golite062009
  • transcription factor activity
    		•  3.50954949535763 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.27542149084008 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.22082323675675 bayes_pls_golite062009
  • binding
    		•  3.10743787485868 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.53101891154822 bayes_pls_golite062009
  • chromatin binding
    		•  2.18464662431232 bayes_pls_golite062009
  • protein binding
    		•  2.05530362750351 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.63161912031789 bayes_pls_golite062009
  • transcription factor binding
    		•  1.39608963544799 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.34049786451995 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.77874411480713 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle