Protein Overview: MP2K7_RAT

General Information:
Name(s) found:	MP2K7_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|70794793\|ref\|NP_001020596.1\| mitogen-activated protein kinase kinase 7 [Rattus norvegicus] [NCBI NR] gi\|62079665\|gb\|AAX61178.1\| mitogen activated protein kinase kinase 7 [Rattus norvegicus] [NCBI NR] gi\|149015608\|gb\|EDL74989.1\| mitogen activated protein kinase kinase 7, isoform CRA_d [Rattus norvegicus] [NCBI NR] gi\|122064485\|sp\|Q4KSH7.1\|MP2K7_RAT RecName: Full=Dual specificity mitogen-activated protein kinase kinase 7; Short=MAP kinase kinase 7; Short=MAPKK 7; AltName: Full=MAPK/ERK kinase 7; AltName: Full=JNK-activating kinase 2; AltName: Full=c-Jun N-terminal k [NCBI NR] Dual specificity mitogen-activated protein kinase kinase 7 OS=Rattus norvegicus GN=Map2k7 PE=1 SV=1 [Swiss-Prot] mitogen activated protein kinase kinase 7 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (MAPK/ERK kinase 7) (JNK-activating kinase 2) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] mitogen activated protein kinase kinase 7, isoform CRA_d [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] mitogen-activated protein kinase kinase 7 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Map2k7 Dual specificity mitogen-activated protein kinase kinase 7 [rat-ipi-250309-contam.fasta] Dual specificity mitogen-activated protein kinase kinase 7 OS=Rattus norvegicus GN=Map2k7 [011711_HMR.fasta] Dual specificity mitogen-activated protein kinase kinase 7 OS=Rattus norvegicus GN=Map2k7 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	419 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][ISS] cytoplasm [ISS] cytosol [IDA]
Biological Process:	activation of JUN kinase activity [IDA] JNK cascade [IDA] protein amino acid phosphorylation [IDA][IEA] response to stress [UNKNOWN][IDA] positive regulation of neuron apoptosis [IMP] stress-activated MAPK cascade [UNKNOWN][IDA]
Molecular Function:	nucleotide binding [IEA] magnesium ion binding [UNKNOWN][IDA] ATP binding [IDA][IEA] protein kinase binding [UNKNOWN] protein tyrosine kinase activity [IEA] protein binding [UNKNOWN][IPI] protein C-terminus binding [IPI] MAP kinase kinase activity [UNKNOWN][IDA] protein serine/threonine kinase activity [IEA] transferase activity [IEA] mitogen-activated protein kinase kinase kinase binding [IPI] JUN kinase kinase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAASSLEQKL SRLEAKLKQE NREARRRIDL NLDISPQRPR PTLQLPLAND GGSRSPSSES  60
   61 SPQHPTPPSR PRHMLGLPST LFTPRSMESI EIDQKLQEIM KQTGYLTIGG QRYQAEINDL 120
  121 ENLGEMGSGT CGQVWKMRFR KTGHIIAVKQ MRRSGNKEEN KRILMDLDVV LKSHDCPYIV 180
  181 QCFGTFITNT DVFIAMELMG TCAEKLKKRM QGPIPERILG KMTVAIVKAL YYLKEKHGVI 240
  241 HRDVKPSNIL LDERGQIKLC DFGISGRLVD SKAKTRSAGC AAYMAPERID PPDPTKPDYD 300
  301 IRADVWSLGI SLVELATGQF PYKNCKTDFE VLTKVLQEEP PLLPGHMGFS GDFQSFVKDC 360
  361 LTKDHRKRPK YNKLLEHSFI KHYETLEVDV ASWFKDVMAK TESPRTSGVL SQHHLPFFR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: MP2K7_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: