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Protein Overview: MP2K7_RAT

General Information:
Name(s) found: MP2K7_RAT [Swiss-Prot]
Description(s) found:
Found 12 descriptions.
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  • Dual specificity mitogen-activated protein kinase kinase 7 OS=Rattus norvegicus GN=Map2k7 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 419 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][ISS]
    cytoplasm [ISS]
    cytosol [IDA]
    Biological Process: activation of JUN kinase activity [IDA]
    JNK cascade [IDA]
    protein amino acid phosphorylation [IDA][IEA]
    response to stress [UNKNOWN][IDA]
    positive regulation of neuron apoptosis [IMP]
    stress-activated MAPK cascade [UNKNOWN][IDA]
    Molecular Function: nucleotide binding [IEA]
    magnesium ion binding [UNKNOWN][IDA]
    ATP binding [IDA][IEA]
    protein kinase binding [UNKNOWN]
    protein tyrosine kinase activity [IEA]
    protein binding [UNKNOWN][IPI]
    protein C-terminus binding [IPI]
    MAP kinase kinase activity [UNKNOWN][IDA]
    protein serine/threonine kinase activity [IEA]
    transferase activity [IEA]
    mitogen-activated protein kinase kinase kinase binding [IPI]
    JUN kinase kinase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAASSLEQKL SRLEAKLKQE NREARRRIDL NLDISPQRPR PTLQLPLAND GGSRSPSSES  60
   61 SPQHPTPPSR PRHMLGLPST LFTPRSMESI EIDQKLQEIM KQTGYLTIGG QRYQAEINDL 120
  121 ENLGEMGSGT CGQVWKMRFR KTGHIIAVKQ MRRSGNKEEN KRILMDLDVV LKSHDCPYIV 180
  181 QCFGTFITNT DVFIAMELMG TCAEKLKKRM QGPIPERILG KMTVAIVKAL YYLKEKHGVI 240
  241 HRDVKPSNIL LDERGQIKLC DFGISGRLVD SKAKTRSAGC AAYMAPERID PPDPTKPDYD 300
  301 IRADVWSLGI SLVELATGQF PYKNCKTDFE VLTKVLQEEP PLLPGHMGFS GDFQSFVKDC 360
  361 LTKDHRKRPK YNKLLEHSFI KHYETLEVDV ASWFKDVMAK TESPRTSGVL SQHHLPFFR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle