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Protein Overview: gi|71911696, gi|...

General Information:
Name(s) found: gi|78707559 [NCBI NR]
gi|71911696 [NCBI NR]
Description(s) found:
Found 5 descriptions.
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  • gi|78707559|ref|NP_611058.3| Z band alternatively spliced PDZ-motif protein, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|71911696|gb|AAF58107.4| Z band alternatively spliced PDZ-motif protein, isoform A [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 1196 amino acids

    Gene Ontology:
    Cellular Component: Z disc [IDA]
    muscle tendon junction [IDA]
    Biological Process: NONE FOUND
    Molecular Function: zinc ion binding [IEA]
    protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQPQLLQIK LSRFDAQPWG FRLQGGTDFA QPLLVQKVNA GSLSEQAGLQ PGDAVVKIND  60
   61 VDVFNLRHKD AQDIVVRSGN NFVITVQRGG STWRPHVTPT GNVPQPNSPY LQTVTKTSLA 120
  121 HKQQDSQHIG CGYNNAARPF SNGGDGGVKS IVNKQYNTPV GIYSDESIAE TLSAQAEVLA 180
  181 GGVLGVNFKK NEKEYQGDRS EVLKFLREEE TGQSTPAFGN SHYEHDAPQQ LQQPQQQYNQ 240
  241 HQQHYHQQQQ QQQSSTTRHV SAPVNSPKPP STGGLPTGQN ICTECERLIT GVFVRIKDKN 300
  301 LHVECFKCAT CGTSLKNQGY YNFNNKLYCD IHAKQAAINN PPTGTEGYVP VPIKPNTKLS 360
  361 ASTISSALNS HGYGGHSNGY SNGNSTPAPA PPESESSQEL PLPPPPSPTQ LLQYEAEQQV 420
  421 LPEPHMSTIQ QPQQQQKLEH TRTHSSLSSI SSGSSSSGAQ SVTNYRLQAA QNENDMNTQN 480
  481 KSPNAYNQLL KEYSNKLQQQ HHHNTTQHTT ATTAPSLKHN NTAKPFAVAA TSTPQQHLPH 540
  541 QQHQQQPLVA ALTATLANQL KFNPHQVASS QATATVATVA PSAATAATAA ATPQAATATD 600
  601 SPAATASSSD NMSAYVADEP SSIYGQISAE SVALAPPPPQ PPTAGGGDQP FEYVTLTGNV 660
  661 IRSVQAPGKG ACPSYKVNQG YARPFGAAAP KSPVSYPPQQ QQQSPRPAPG GQNPYATLPR 720
  721 SNVGQQVPTG AQSAAKSTNL HASPQTFATL PRPHPQATDI PAQELQKDNQ LESDATSMLA 780
  781 ESVGKINMGD KTQAFMQEAG KIITNMLEAR LANNGGQNGP LSHAGSSLSL RSNSSSNLSK 840
  841 SPMIVRKRLD LDDFKNLDPT QPVALQPVIA VHSQKDLPTE VGNQKAQPQA PRLEQTLQME 900
  901 LAAQHPMGKI LDLCDGGKAI DTPEPVAFRN NLKRTGATHA ADRRSYIEPK QGAINATSVA 960
  961 TQNGNQNGGQ AGNQNATQGS APTYSVSVKA LGPHSEDQTT MSEENERAVS QLLKEGKRPV1020
 1021 CCQCNKEITS GPFITALGRI WCPDHFICVN GNCRRPLQDI GFVEEKGDLY CEYCFEKYLA1080
 1081 PTCSKCAGKI KGDCLNAIGK HFHPECFTCG QCGKIFGNRP FFLEDGNAYC EADWNELFTT1140
 1141 KCFACGFPVE AGDRWVEALN HNYHSQCFNC TFCKQNLEGQ SFYNKGGRPF CKNHAR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..183] PSI-BLAST 24.522879 Solution structure of PDZ domain of mouse Alpha-actinin-2 associated LIM protein
    2 View Details [184..267] deduced N/A No confident structure predictions are available.
    3 View Details [268..355] PSI-BLAST 7.0 Solution structure of the LIM domain of alpha-actinin-2 associated LIM protein
    4 View Details [356..541] deduced N/A No confident structure predictions are available.
    5 View Details [542..729] deduced N/A No confident structure predictions are available.
    6 View Details [730..847] deduced N/A No confident structure predictions are available.
    7 View Details [848..1040] PSI-BLAST 35.045757 No description for 2i13A was found.
    8 View Details [1041..1100] FFAS03 1.74 Cysteine-rich (intestinal) protein, CRP, CRIP
    9 View Details [1101..1196] PSI-BLAST 15.39794 Ying-yang 1 (yy1, zinc finger domain)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • structural constituent of muscle
    		•  3.94885944537237 bayes_pls_golite062009
  • actin binding
    		•  3.71885072001885 bayes_pls_golite062009
  • actinin binding
    		•  3.61513078757793 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.60106431937699 bayes_pls_golite062009
  • binding
    		•  3.2595117613307 bayes_pls_golite062009
  • protein binding
    		•  2.35875654816667 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.16834620509051 bayes_pls_golite062009
  • actin filament binding
    		•  1.91421788587359 bayes_pls_golite062009
  • myosin binding
    		•  1.34447751574529 bayes_pls_golite062009
  • alpha-actinin binding
    		•  0.81785989473612 bayes_pls_golite062009
  • transporter activity
    		•  0.782216866213126 bayes_pls_golite062009
  • structural molecule activity
    		•  0.745651480925433 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.699604120098573 bayes_pls_golite062009
  • PDZ domain binding
    		•  0.53069705861477 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.434921764966531 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.30840185305841 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.250590541549843 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.211809989510755 bayes_pls_golite062009
  • signal transducer activity
    		•  0.211809989510755 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.182094987832726 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.171693460058476 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0433431329070377 bayes_pls_golite062009
  • transcription factor binding
    		•  0.0283953080227368 bayes_pls_golite062009
  • receptor binding
    		•  0.00333430733556384 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  4.00967542385368 bayes_pls_golite062009
  • DNA binding
    		•  3.60745514727532 bayes_pls_golite062009
  • actin binding
    		•  3.16886380675327 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.16757861573985 bayes_pls_golite062009
  • binding
    		•  2.96409924710655 bayes_pls_golite062009
  • transcription factor activity
    		•  2.90769972671972 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.31497455728997 bayes_pls_golite062009
  • actin filament binding
    		•  1.88919389919607 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.62841402245495 bayes_pls_golite062009
  • transcription activator activity
    		•  1.62405765585032 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.59407701118798 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.50210964370113 bayes_pls_golite062009
  • ligand-dependent nuclear receptor activity
    		•  1.49515149729803 bayes_pls_golite062009
  • protein binding
    		•  1.39455913713025 bayes_pls_golite062009
  • transcription factor binding
    		•  1.38523780690867 bayes_pls_golite062009
  • receptor activity
    		•  1.2947757480478 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.14370842685155 bayes_pls_golite062009
  • structural molecule activity
    		•  1.03433454627943 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.02134399426658 bayes_pls_golite062009
  • signal transducer activity
    		•  1.02134399426658 bayes_pls_golite062009
  • transporter activity
    		•  0.883869495141753 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.69816175939074 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.68270103300828 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.61572149323953 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.58115018700114 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.480921069521595 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.256420113528322 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.248246733554633 bayes_pls_golite062009
  • myosin binding
    		•  0.208886721497353 bayes_pls_golite062009
  • catalytic activity
    		•  0.101795606736461 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle