| Protein: | gi|71911696, gi|... |
| Organism: | Drosophila melanogaster |
| Length: | 1196 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|71911696, gi|....
| Description | E-value | Query Range |
Subject Range |
|
|
737.0 | [0..204] | [1190..324] |
|
Region A: Residues: [1-183] |
1 11 21 31 41 51
| | | | | |
1 MAQPQLLQIK LSRFDAQPWG FRLQGGTDFA QPLLVQKVNA GSLSEQAGLQ PGDAVVKIND 60
61 VDVFNLRHKD AQDIVVRSGN NFVITVQRGG STWRPHVTPT GNVPQPNSPY LQTVTKTSLA 120
121 HKQQDSQHIG CGYNNAARPF SNGGDGGVKS IVNKQYNTPV GIYSDESIAE TLSAQAEVLA 180
181 GGV
|
| Detection Method: |  |
| Confidence: | 24.522879 |
| Match: | 1v5lA |
| Description: | Solution structure of PDZ domain of mouse Alpha-actinin-2 associated LIM protein |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| structural constituent of muscle | 3.94885944537237 | bayes_pls_golite062009 |
| actin binding | 3.71885072001885 | bayes_pls_golite062009 |
| actinin binding | 3.61513078757793 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 3.60106431937699 | bayes_pls_golite062009 |
| binding | 3.2595117613307 | bayes_pls_golite062009 |
| protein binding | 2.35875654816667 | bayes_pls_golite062009 |
| transcription regulator activity | 2.16834620509051 | bayes_pls_golite062009 |
| actin filament binding | 1.91421788587359 | bayes_pls_golite062009 |
| myosin binding | 1.34447751574529 | bayes_pls_golite062009 |
| alpha-actinin binding | 0.81785989473612 | bayes_pls_golite062009 |
| transporter activity | 0.782216866213126 | bayes_pls_golite062009 |
| structural molecule activity | 0.745651480925433 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.699604120098573 | bayes_pls_golite062009 |
| PDZ domain binding | 0.53069705861477 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.434921764966531 | bayes_pls_golite062009 |
| protein domain specific binding | 0.30840185305841 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.250590541549843 | bayes_pls_golite062009 |
| molecular transducer activity | 0.211809989510755 | bayes_pls_golite062009 |
| signal transducer activity | 0.211809989510755 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.182094987832726 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.171693460058476 | bayes_pls_golite062009 |
| transcription activator activity | 0.0433431329070377 | bayes_pls_golite062009 |
| transcription factor binding | 0.0283953080227368 | bayes_pls_golite062009 |
| receptor binding | 0.00333430733556384 | bayes_pls_golite062009 |
|
Region A: Residues: [184-267] |
1 11 21 31 41 51
| | | | | |
1 LGVNFKKNEK EYQGDRSEVL KFLREEETGQ STPAFGNSHY EHDAPQQLQQ PQQQYNQHQQ 60
61 HYHQQQQQQQ SSTTRHVSAP VNSP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [268-355] |
1 11 21 31 41 51
| | | | | |
1 KPPSTGGLPT GQNICTECER LITGVFVRIK DKNLHVECFK CATCGTSLKN QGYYNFNNKL 60
61 YCDIHAKQAA INNPPTGTEG YVPVPIKP
|
| Detection Method: | |
| Confidence: | 7.0 |
| Match: | 1x64A |
| Description: | Solution structure of the LIM domain of alpha-actinin-2 associated LIM protein |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 4.00967542385368 | bayes_pls_golite062009 |
| DNA binding | 3.60745514727532 | bayes_pls_golite062009 |
| actin binding | 3.16886380675327 | bayes_pls_golite062009 |
| nucleic acid binding | 3.16757861573985 | bayes_pls_golite062009 |
| binding | 2.96409924710655 | bayes_pls_golite062009 |
| transcription factor activity | 2.90769972671972 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.31497455728997 | bayes_pls_golite062009 |
| actin filament binding | 1.88919389919607 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.62841402245495 | bayes_pls_golite062009 |
| transcription activator activity | 1.62405765585032 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.59407701118798 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 1.50210964370113 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 1.49515149729803 | bayes_pls_golite062009 |
| protein binding | 1.39455913713025 | bayes_pls_golite062009 |
| transcription factor binding | 1.38523780690867 | bayes_pls_golite062009 |
| receptor activity | 1.2947757480478 | bayes_pls_golite062009 |
| structural constituent of ribosome | 1.14370842685155 | bayes_pls_golite062009 |
| structural molecule activity | 1.03433454627943 | bayes_pls_golite062009 |
| molecular transducer activity | 1.02134399426658 | bayes_pls_golite062009 |
| signal transducer activity | 1.02134399426658 | bayes_pls_golite062009 |
| transporter activity | 0.883869495141753 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.69816175939074 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 0.68270103300828 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.61572149323953 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.58115018700114 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.480921069521595 | bayes_pls_golite062009 |
| transcription repressor activity | 0.256420113528322 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.248246733554633 | bayes_pls_golite062009 |
| myosin binding | 0.208886721497353 | bayes_pls_golite062009 |
| catalytic activity | 0.101795606736461 | bayes_pls_golite062009 |
|
Region A: Residues: [356-541] |
1 11 21 31 41 51
| | | | | |
1 NTKLSASTIS SALNSHGYGG HSNGYSNGNS TPAPAPPESE SSQELPLPPP PSPTQLLQYE 60
61 AEQQVLPEPH MSTIQQPQQQ QKLEHTRTHS SLSSISSGSS SSGAQSVTNY RLQAAQNEND 120
121 MNTQNKSPNA YNQLLKEYSN KLQQQHHHNT TQHTTATTAP SLKHNNTAKP FAVAATSTPQ 180
181 QHLPHQ
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [542-729] |
1 11 21 31 41 51
| | | | | |
1 QHQQQPLVAA LTATLANQLK FNPHQVASSQ ATATVATVAP SAATAATAAA TPQAATATDS 60
61 PAATASSSDN MSAYVADEPS SIYGQISAES VALAPPPPQP PTAGGGDQPF EYVTLTGNVI 120
121 RSVQAPGKGA CPSYKVNQGY ARPFGAAAPK SPVSYPPQQQ QQSPRPAPGG QNPYATLPRS 180
181 NVGQQVPT
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [730-847] |
1 11 21 31 41 51
| | | | | |
1 GAQSAAKSTN LHASPQTFAT LPRPHPQATD IPAQELQKDN QLESDATSML AESVGKINMG 60
61 DKTQAFMQEA GKIITNMLEA RLANNGGQNG PLSHAGSSLS LRSNSSSNLS KSPMIVRK
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [848-1040] |
1 11 21 31 41 51
| | | | | |
1 RLDLDDFKNL DPTQPVALQP VIAVHSQKDL PTEVGNQKAQ PQAPRLEQTL QMELAAQHPM 60
61 GKILDLCDGG KAIDTPEPVA FRNNLKRTGA THAADRRSYI EPKQGAINAT SVATQNGNQN 120
121 GGQAGNQNAT QGSAPTYSVS VKALGPHSED QTTMSEENER AVSQLLKEGK RPVCCQCNKE 180
181 ITSGPFITAL GRI
|
| Detection Method: | |
| Confidence: | 35.045757 |
| Match: | 2i13A |
| Description: | No description for 2i13A was found. |
|
Region A: Residues: [1041-1100] |
1 11 21 31 41 51
| | | | | |
1 WCPDHFICVN GNCRRPLQDI GFVEEKGDLY CEYCFEKYLA PTCSKCAGKI KGDCLNAIGK 60
61
|
| Detection Method: | |
| Confidence: | 1.74 |
| Match: | 1cxxA |
| Description: | Cysteine-rich (intestinal) protein, CRP, CRIP |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1101-1196] |
1 11 21 31 41 51
| | | | | |
1 HFHPECFTCG QCGKIFGNRP FFLEDGNAYC EADWNELFTT KCFACGFPVE AGDRWVEALN 60
61 HNYHSQCFNC TFCKQNLEGQ SFYNKGGRPF CKNHAR
|
| Detection Method: | |
| Confidence: | 15.39794 |
| Match: | 1ubdC |
| Description: | Ying-yang 1 (yy1, zinc finger domain) |
Matching Structure (courtesy of the PDB): |
|
