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Protein Overview: gi|62665251

General Information:
Name(s) found: gi|62665251 [NCBI NR]
Description(s) found:
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  • gi|62665251|ref|XP_226464.3| PREDICTED: similar to Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1) [Rattus norvegicus] [NCBI NR]
  • Tax_Id=10116 PREDICTED: similar to AT motif-binding factor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • PREDICTED: similar to Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Zfhx3 similar to Alpha-fetoprotein enhancer-binding protein [rat-ipi-250309-contam.fasta]
    • Organism: Rattus norvegicus
    Length: 3730 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][IEA]
    transcription factor complex [UNKNOWN]
    cytoplasm [IDA]
    mitochondrion [UNKNOWN]
    intracellular [IEA]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter [UNKNOWN]
    cell cycle arrest [IEP]
    negative regulation of myoblast differentiation [UNKNOWN]
    regulation of transcription, DNA-dependent [IEA]
    positive regulation of myoblast differentiation [UNKNOWN]
    brain development [IEP]
    regulation of neuron differentiation [IEP]
    Molecular Function: transcription factor activity [IEA]
    zinc ion binding [IEA]
    sequence-specific DNA binding [IEA]
    promoter binding [UNKNOWN]
    transcription repressor activity [UNKNOWN]
    molecular_function [ND]
    enzyme binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGCDSPVVS GKDNGCGIPQ HRQWTELNST HLPDKPSSME QPTGESHGPL DSLRAPFNER  60
   61 LADSSTSAGP PAEPASKEVS CNECSASFSS LQTYMEHHCP GTHPPPALRE ESASDTSEEG 120
  121 EEESDVENLA GEIVYQPDGS AYIVESLSQL AQSGAACGSS SGSGGVPSLF LNSLPGVGGK 180
  181 QGDPSCAAPV YPQIINTFHI ASSFGKWFEG SDQAFPNTSA LAGLSPVLHS FRVFDVRHKS 240
  241 NKDYLNSDGS AKSSCVSKDV PNNVDLSKFD GFVLYGKRKP ILMCFLCKLS FGYVRSFVTH 300
  301 AVHDHRMTLS EEERKLLSNK NTSAIIQGIG KDKEPLVSFL EPKNKNFQHP LVSTANLIGP 360
  361 GHSFYGKFSG ICMDGEEALP AGAAAGPEQP QAGLLTPSTL LNLGGLTSSV LKTPITSVPL 420
  421 GPLASSPTKS SEGKDSGAAE GDKREVGDQD CFSEKVEPAE EEEAEEEEEE EEEAEEEEEE 480
  481 EEEEEEEDEG CKGLFPNELE EELEDRPPEE SGATAGGGSK KDLALSNQSI SNSPLMPNVL 540
  541 QTLSRGTAST TSNSASNFVV FDGANRRSRL SFNSEGVRAN VAEGRRLDFA DESANKDSAT 600
  601 APEPNESTEG DDGGFAPHHQ HAGSLCELGV GECPSGSGVE CPKCDTVLGS SRSLGGHMTM 660
  661 MHSRNSCKTL KCPKCNWHYK YQQTLEAHMK EKHPEPGGSC VYCKSGQPHP RLARGESYTC 720
  721 GYKPFRCEVC NYSTTTKGNL SIHMQSDKHL NNMQNLQNGG GEQVFSHSAG AAAAAAAAAA 780
  781 AAANIGSSCG APSPTKPKTK PTWRCEVCDY ETNVARNLRI HMTSEKHMHN MMLLQQNMTQ 840
  841 IQHNRHLGLG SLPSPAEAEL YQYYLAQNMN LPNLKMDNTA SDAQFMMSGF QLDPTGPMAA 900
  901 MTPALVGGEI PLDMRLGGGQ LVSEELMNLG ESFIQTNDPS LKLFQCAVCN KFTTDNLDML 960
  961 GLHMNVERSL SEDEWKAVMG DSYQCKLCRY NTQLKANFQL HCKTDKHVQK YQLVAHIKEG1020
 1021 GKANEWRLKC VAIGNPVHLK CNACDYYTNS LEKLRLHTVN SRHEASLKLY KHLQQHESGV1080
 1081 EGESCYYHCV LCNYSTKAKL NLIQHVRSMK HQRSESLRKL QRLQKGLPEE DEDLGQIFTI1140
 1141 RRCPSTDPEE AIEDAEGPSE ASADPEELAK DQGSSGGEEG QSKRTASSSQ AEKELTDSPA1200
 1201 ASKRSSFPGS SETPLSSKRP KASEEIKPEQ MYQCPYCKYS NADVNRLRVH AMTQHSVQPM1260
 1261 LRCPLCQDML NNKIHLQLHL THLHSVAPDC VEKLIMTVTA PEMVMPSSMF LPAAAPDRDG1320
 1321 NPNLEEAGKQ PETSEDLGKN TLPSAIMEHS GDLKPSSADP SCMREDSGFL CWKKGCNQVF1380
 1381 KTSATLQTHF NEVHAKRPQL PVSDRHVYKY RCNQCSLAFK TIEKLQLHSQ YHVIRAATMC1440
 1441 CLCQRSFRTF QALKKHLETS HLELSEADIQ QLYGGLLANG DLLAMGDPTL AEDHTIIVEE1500
 1501 DKEEESDLED KQSPTGSDSG SVQEDSGSEP KRALPFRKGP NFTMEKFLDP SRPYKCTVCK1560
 1561 ESFTQKNILL VHYNSVSHLH KLKRALQESA TGQPEPTSSP DNKPFKCNTC NVAYSQSSTL1620
 1621 EIHMRSVLHQ TKARAAKLEA ASGSSNGTGN SAGVSLSSST PSPVGSSGAN NTFTAANPSS1680
 1681 ATMAPSVNAL SQVPPESVVL PPLGNPISAN ISSPSEPKET NRKKLADMIA SRQQQQQQQQ1740
 1741 QQQQQQAQTL AQAQAQVQAH LQQELQQQAA LIQSQLFNPT LLPHFPMTTE TLLQLQQQHH1800
 1801 LLFPFYIPSA EFQLNPEVSL PVTSGALTLT GSGPGLLEDL KAQIQIPQQS HPQILQQQQQ1860
 1861 QQQQQSQLSL SQSHSALLQP SQHPEKKNKV VIKEKDKESQ REREGPEGAE GNPGPKESLP1920
 1921 DALKAKEKKE LAPGGGSEGS MLPPRIASDA RGNATKALLE NFGFELVIQY NENKQKAQKK1980
 1981 NGKAEQGSES LEKLECDSCG KLFSNILILK SHQEHVHQNY FPFKQLERFA KQYREHYDKL2040
 2041 YPLRPQTPEP PPPPPPPPPP PLPAAPPQPA STPAIPASAP PITSPTIAPA QPSVPLTQLS2100
 2101 MPMELPIFSP LMMQTMPLQT LPAQLPPQLG PVEPLPADLA QLYQHQLNPT LLQQQNKRPR2160
 2161 TRITDDQLRV LRQYFDINNS PSEEQIKEMA DKSGLPQKVI KHWFRNTLFK ERQRNKDSPY2220
 2221 NFSNPPITSL EELKIDSRPP SPEPQKQEYW GSKRSSRTRF TDYQLRVLQD FFDANAYPKD2280
 2281 DEFEQLSNLL NLPTRVIVVW FQNARQKARK NYENQGEGKD GERRELTNDR YIRTSNLNYQ2340
 2341 CKKCSLVFQR IFDLIKHQKK LCYKDEDEEG QDDSQNEDSM DAMEILTPTS SSCSTPMPSQ2400
 2401 AYSTPAPSSA STAPSAFLQL TAETDELATF NSKAEASDEK PKQADPPSVQ PNQTQEKQGQ2460
 2461 PKPEVQQQEQ AEQKTNVPQP KLPQLAAPSL PQPPPQAPPP QCPLPQSSPS PSQLSHLPLK2520
 2521 PLHTSTPQQL ANLPPQLIPY QCDQCKLAFP SFEHWQEHQQ LHFLSAQNQF IHPQFLDRSL2580
 2581 DMPFMLFDPS NPLLASQLLS GAIPQIPASS ATSPSTPTST MNTLKRKLEE KASGASPGEN2640
 2641 DSSGTGGEEP QRDKRLRTTI TPEQLEILYQ KYLLDSNPTR KMLDHIAHEV GLKKRVVQVW2700
 2701 FQNTRARERK GQFRAVGPAQ AHRRCPFCRA LFKAKTALEA HIRSRHWHEA KRAGYNLTLS2760
 2761 AMLLDCDGGL QMKGDIFDGT SFSHLPPSGS DGQGVPLSPV SKTMELSPRT LLSPSSIKVE2820
 2821 GLEDFESPSM SSVNLNFDQT KLDNDDCSSV NTAITDTTTG DEGNADNDSA TGIANETKSS2880
 2881 APNEGLTKAA MMAMSEYEDR LSSGLVSPAP SFYSKEYDNE GTVDYSETSS LADPCSPSPG2940
 2941 ASGSAGKSGD SGDRPGQKRF RTQMTNLQLK VLKSCFNDYR TPTMLECEVL GNDIGLPKRV3000
 3001 VQVWFQNARA KEKKSKLSMA KHFGINQTSY EGPKTECTLC GIKYSARLSV RDHIFSQQHI3060
 3061 SKVKDTIGSQ LDKEKEYFDP ATVRQLMAQQ ELDRIKKANE VLGLAAQQQG MFDNAPLQAL3120
 3121 NLPTTYPALQ GIPPVLLPGL NSPSLPGFTP SNTALTSPKP NLMGLPSTTV PSPGLPTSGL3180
 3181 PNKPSSASLS SPTPAQATMA MAPQQPPQPQ QPQPQVQPPP PPAAQQIPTP QLPLPQQRKD3240
 3241 KDGEKGKEKE KAHKGKGEPP PVPKKEKGEA PTAATATISA PLPAMEYTVD PAQLQALQAA3300
 3301 LTSDPTALLT SQFLPYFVPG FSPYYAPQIP GALQSGYLQP MYGMEGLFPY SPALSQALMG3360
 3361 LSPGSLLQQY QQYQQSLQEA IQQQQQQQQQ QQQQQQRQLQ QQQQQQQKVQ QQQQQQQQQQ3420
 3421 QQQQPKASQT PVPQGPASPD KDPAKESPKP EEQKNVPREV SPLLPKPPEE PEAESKSASA3480
 3481 DSLCDPFIVP KVQYKLVCRK CQAGFGDEEA ARSHLKSLCF FGQSVVNLQE MVLHVPTGSG3540
 3541 GGGGGGGSGG GGGGSYHCLA CESALCGEEA LSQHLESALH KHRTITRAAR NAKEHPSLLP3600
 3601 HSACFPDPST ASTSQSAAHS NDSPPPPSAA PSSSASPHAS RKSWPPVGSR ASAAKPPSFP3660
 3661 PLSSSSTVTS SSCSTSGVQP SMPTDDYSEE SDTDLSQKSD GPASPVEGPK DPSCPKDSGL3720
 3721 TSVGTDTFRL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle