Protein Overview: gi|62653804

General Information:
Name(s) found:	gi\|62653804 [NCBI NR]
Description(s) found: SHOW ONLY BEST	gi\|62653804\|ref\|XP_345948.2\| PREDICTED: similar to Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against DPP homolog 6) (Smad6) (Mad homolog 7) [Rattus norvegicus] [NCBI NR] Tax_Id=10116 PREDICTED: similar to Smad6 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] PREDICTED: similar to Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against DPP homolog 6) (Smad6) (Mad homolog 7) [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Smad6 SMAD family member 6 [rat-ipi-250309-contam.fasta] Uncharacterized protein OS=Rattus norvegicus GN=Smad6 [011711_HMR.fasta] Uncharacterized protein OS=Rattus norvegicus GN=Smad6 PE=4 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta] Protein Smad6 OS=Rattus norvegicus GN=Smad6 PE=4 SV=1 [Aridor_1205.fasta]
Organism:	Rattus norvegicus
Length:	495 amino acids
Gene Ontology:
Cellular Component:	transcription factor complex [IEA] cytosol [UNKNOWN] cellular_component [ND] intracellular [IEA]
Biological Process:	response to estrogen stimulus [IEP] zygotic specification of dorsal/ventral axis [UNKNOWN] negative regulation of pathway-restricted SMAD protein phosphorylation [UNKNOWN] transforming growth factor beta receptor signaling pathway [IEA] regulation of transcription, DNA-dependent [IEA] negative regulation of BMP signaling pathway [UNKNOWN] immune response [UNKNOWN] response to laminar fluid shear stress [UNKNOWN] ureteric bud development [UNKNOWN] positive regulation of S phase of mitotic cell cycle [UNKNOWN] BMP signaling pathway [UNKNOWN] negative regulation of apoptosis [UNKNOWN] negative regulation of caspase activity [UNKNOWN] negative regulation of SMAD protein complex assembly [UNKNOWN] negative regulation of transforming growth factor beta receptor signaling pathway [UNKNOWN]
Molecular Function:	transcription factor activity [IEA] protein binding [UNKNOWN][IEA] ubiquitin protein ligase binding [UNKNOWN] transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity [UNKNOWN] R-SMAD binding [UNKNOWN] type I activin receptor binding [UNKNOWN] co-SMAD binding [UNKNOWN] I-SMAD binding [UNKNOWN] type I transforming growth factor beta receptor binding [UNKNOWN] molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRSKRSGLV RRLWRSRVVP DREEGSGGGC GGDEDGSLGS RAEPAPRARE GGGCGRSEVR  60
   61 SVAPRRLRDA VGPRGALIAG RRRRTGGPPR PVSEPGAGAG GSPLDVVEPG GPGWLPESDC 120
  121 ETVTCCLFSE RDAAGAPRDS GDPQARQSPE PEEGGGPRSR EARSRLLLLE QELKTVTYSL 180
  181 LKRLKERSLD TLLEAVESRG GVPGGCVLVP RADLRLGGQP APPQLLLGRL FRWPDLQHAV 240
  241 ELKPLCGCHS FAAAADGPTV CCNPYHFSRL CGPESPPPPY SRLSPPDQHK PLDLSDSTLS 300
  301 YTETEATNSL ITAPGEFSDA SMSPDATKPS HWCSVAYWEH RTRVGRLYAV YDQAVSIFYD 360
  361 LPQGSGFCLG QLNLEQRSES VRRTRSKIGF GILLSKEPDG VWAYNRGEHP IFVNSPTLDA 420
  421 PGGRALVVRK VPPGYSIKVF DFERSGLLQH ADAAHGPYDP HSVRISFAKG WGPCYSRQFI 480
  481 TSCPCWLEIL LNNHR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: gi|62653804

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: