Protein Overview: DPP4_RAT

General Information:
Name(s) found:	DPP4_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|56405289\|sp\|P14740.2\|DPP4_RAT RecName: Full=Dipeptidyl peptidase 4; AltName: Full=Dipeptidyl peptidase IV; Short=DPP IV; AltName: Full=T-cell activation antigen CD26; AltName: Full=GP110 glycoprotein; AltName: Full=Bile canaliculus domain-specific memb [NCBI NR] Dipeptidyl peptidase 4 OS=Rattus norvegicus GN=Dpp4 PE=1 SV=2 [Swiss-Prot] Tax_Id=10116 Dipeptidyl peptidase 4 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Dipeptidyl peptidase IV [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] Dipeptidyl peptidase 4 (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (GP110 glycoprotein) (Bile canaliculus domain-specific membrane glycoprotein) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Dpp4 Dipeptidyl peptidase 4 [rat-ipi-250309-contam.fasta] Dipeptidyl peptidase 4 OS=Rattus norvegicus GN=Dpp4 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	767 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum [IDA] Golgi apparatus [IDA] extracellular region [IEA] plasma membrane [UNKNOWN][IDA] cell surface [UNKNOWN][IDA][IMP][ISS] membrane fraction [IDA] intercellular canaliculus [UNKNOWN][IEA] endocytic vesicle [UNKNOWN][ISS] soluble fraction [IDA] membrane raft [IEA] integral to membrane [IEA] cell junction [IEA] apical plasma membrane [UNKNOWN][IEA] lamellipodium [UNKNOWN][ISS] lamellipodium membrane [IEA] invadopodium membrane [UNKNOWN][ISS]
Biological Process:	response to hypoxia [UNKNOWN][IEA] establishment of localization [IMP] T cell costimulation [UNKNOWN][ISS] negative regulation of extracellular matrix disassembly [UNKNOWN][ISS] proteolysis [IDA][TAS] positive regulation of cell proliferation [UNKNOWN][ISS] regulation of cell-cell adhesion mediated by integrin [UNKNOWN][IEA] T cell activation [UNKNOWN][IEA] cell adhesion [IEA] endothelial cell migration [UNKNOWN][ISS] regulation of T cell mediated immunity [IMP]
Molecular Function:	protein binding [UNKNOWN] protein homodimerization activity [UNKNOWN][IDA][IMP][ISS] collagen binding [IDA] serine-type endopeptidase activity [IEA] serine-type peptidase activity [UNKNOWN] protease binding [UNKNOWN][ISS] aminopeptidase activity [IEA] peptide binding [IDA] peptidase activity [IEA] receptor binding [UNKNOWN][ISS] dipeptidyl-peptidase activity [UNKNOWN][IDA][IMP][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTPWKVLLG LLGVAALVTI ITVPVVLLNK DEAAADSRRT YTLADYLKNT FRVKSYSLRW  60
   61 VSDSEYLYKQ ENNILLFNAE HGNSSIFLEN STFEIFGDSI SDYSVSPDRL FVLLEYNYVK 120
  121 QWRHSYTASY SIYDLNKRQL ITEEKIPNNT QWITWSQEGH KLAYVWKNDI YVKIEPHLPS 180
  181 HRITSTGKEN VIFNGINDWV YEEEIFGAYS ALWWSPNGTF LAYAQFNDTG VPLIEYSFYS 240
  241 DESLQYPKTV WIPYPKAGAV NPTVKFFIVN TDSLSSTTTT IPMQITAPAS VTTGDHYLCD 300
  301 VAWVSEDRIS LQWLRRIQNY SVMAICDYDK TTLVWNCPTT QEHIETSATG WCGRFRPAEP 360
  361 HFTSDGSSFY KIVSDKDGYK HICQFQKDRK PEQVCTFITK GAWEVISIEA LTSDYLYYIS 420
  421 NEYKEMPGGR NLYKIQLTDH TNKKCLSCDL NPERCQYYSV SLSKEAKYYQ LGCRGPGLPL 480
  481 YTLHRSTDQK ELRVLEDNSA LDKMLQDVQM PSKKLDFIVL NETRFWYQMI LPPHFDKSKK 540
  541 YPLLIDVYAG PCSQKADAAF RLNWATYLAS TENIIVASFD GRGSGYQGDK IMHAINKRLG 600
  601 TLEVEDQIEA ARQFLKMGFV DSKRVAIWGW SYGGYVTSMV LGSGSGVFKC GIAVAPVSRW 660
  661 EYYDSVYTER YMGLPTPEDN LDHYRNSTVM SRAENFKQVE YLLIHGTADD NVHFQQSAQI 720
  721 SKALVDAGVD FQAMWYTDED HGIASSTAHQ HIYSHMSHFL QQCFSLR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: DPP4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: