Protein Overview: egg-PA

General Information:
Name(s) found:	egg-PA / FBpp0111689 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|78214272\|gb\|ABB36451.1\| IP14531p [Drosophila melanogaster] [NCBI NR] gi\|161077479\|ref\|NP_611966.3\| eggless [Drosophila melanogaster] [NCBI NR] gi\|157400490\|gb\|AAF47268.3\| eggless [Drosophila melanogaster] [NCBI NR] gi\|122123186\|sp\|Q32KD2.1\|SETB1_DROME RecName: Full=Histone-lysine N-methyltransferase eggless; AltName: Full=SETDB1 homolog [NCBI NR] Histone-lysine N-methyltransferase eggless OS=Drosophila melanogaster GN=egg PE=1 SV=1 [Swiss-Prot] The gene eggless is referred to in FlyBase by the symbol Dmel\egg (CG12196, FBgn0086908). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20663057..20667437. It has the cytological map location 60E1. There is experimental evidence that it has the molecular function</span>: protein binding; histone methyltransferase activity (H3-K9 specific). There is experimental evidence that it is involved in the biological process</span>: wing disc development; histone methylation; regulation of gene expression, epigenetic; histone H3-K9 methylation; instar larval or pupal development; oogenesis. 13 alleles are reported. The phenotypes of these alleles are annotated with: germline cyst; egg; ovary; follicle cell; wing; egg chamber; germarium. It has one annotated transcript and one annotated polypeptide. [FlyBase] (AE003465) CG12196 gene product [Drosophila melanogaster] [yeastflysequest.fasta] type=protein; loc=2R:complement(20663117..20663323,20663382..20664098,20664170..20664931,20664990..20665495,20665558..20665813,20665867..20666150,20666222..20666339,20666398..20667336); ID=FBpp0111689; name=egg-PA; parent=FBgn0086908,FBtr0112777; dbxref=G [fly-100309-contam.fasta] IP14531p [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2R:complement(20663117..20663323,20663382..20664098,20664170..20664931,20664990..20665495,20665558..20665813,20665867..20666150,20666222..20666339,20666398..20667336); ID=FBpp0111689; name=egg-PA; parent=FBgn0086908,FBtr0112777; dbxref=GB_protein:AAM70794,FlyBase:FBpp0072337,GB_protein:AAF47268.2,GB_protein:AAM70794.1,FlyBase:FBpp0111689,GB_protein:AAF47268,FlyBase:FBpp0072336,FlyBase_Annotation_IDs:CG12196-PA,FlyBase_Annotation_IDs:CG30422-PA,FlyBase_Annotation_IDs:CG30426-PA,REFSEQ:NP_611966,GB_protein:AAF47268; MD5=ae8598e9e42cb355130866aacbbaa539; length=1262; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2R:complement(20663117..20663323,20663382..20664098,20664170..20664931,20664990..20665495,20665558..20665813,20665867..20666150,20666222..20666339,20666398..20667336); ID=FBpp0111689; name=egg-PA; parent=FBgn0086908,FBtr0112777; dbxref=GB_protein:AAM70794,FlyBase:FBpp0072337,GB_protein:AAF47268.2,GB_protein:AAM70794.1,FlyBase:FBpp0111689,GB_protein:AAF47268,FlyBase:FBpp0072336,FlyBase_Annotation_IDs:CG12196-PA,FlyBase_Annotation_IDs:CG30422-PA,FlyBase_Annotation_IDs:CG30426-PA,REFSEQ:NP_611966,GB_protein:AAF47268; MD5=ae8598e9e42cb355130866aacbbaa539; length=1262; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=2R:complement(20663117..20663323,20663382..20664098,20664170..20664931,20664990..20665495,20665558..20665813,20665867..20666150,20666222..20666339,20666398..20667336); ID=FBpp0111689; name=egg-PA; parent=FBgn0086908,FBtr0112777; dbxref=GB_protein:AAM70794,FlyBase:FBpp0072337,GB_protein:AAF47268.2,GB_protein:AAM70794.1,FlyBase:FBpp0111689,GB_protein:AAF47268,FlyBase:FBpp0072336,FlyBase_Annotation_IDs:CG12196-PA,FlyBase_Annotation_IDs:CG30422-PA,FlyBase_Annotation_IDs:CG30426-PA,REFSEQ:NP_611966,GB_protein:AAF47268,FlyMine:FBpp0111689,modMine:FBpp0111689; MD5=ae8598e9e42cb355130866aacbbaa539; length=1262; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2R:complement(join(24778875..24779813,24778699..24778816,24778344..24778627,24778035..24778290,24777467..24777972,24776647..24777408,24775859..24776575,24775594..24775800)); ID=FBpp0111689; name=egg-PA; parent=FBgn0086908,FBtr0112777; dbxref=GB_protein:AAM70794,FlyBase:FBpp0072337,GB_protein:AAF47268.2,GB_protein:AAM70794.1,FlyBase:FBpp0111689,GB_protein:AAF47268,FlyBase:FBpp0072336,FlyBase_Annotation_IDs:CG12196-PA,FlyBase_Annotation_IDs:CG30422-PA,FlyBase_Annotation_IDs:CG30426-PA,REFSEQ:NP_611966,GB_protein:AAF47268,FlyMine:FBpp0111689,modMine:FBpp0111689; MD5=ae8598e9e42cb355130866aacbbaa539; length=1262; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2R:complement(join(24778875..24779813,24778699..24778816,24778344..24778627,24778035..24778290,24777467..24777972,24776647..24777408,24775859..24776575,24775594..24775800)); ID=FBpp0111689; name=egg-PA; parent=FBgn0086908,FBtr0112777; dbxref=GB_protein:AAM70794,FlyBase:FBpp0072337,GB_protein:AAF47268.2,GB_protein:AAM70794.1,FlyBase:FBpp0111689,GB_protein:AAF47268,FlyBase:FBpp0072336,FlyBase_Annotation_IDs:CG12196-PA,FlyBase_Annotation_IDs:CG30422-PA,FlyBase_Annotation_IDs:CG30426-PA,REFSEQ:NP_611966,GB_protein:AAF47268,FlyMine:FBpp0111689,modMine:FBpp0111689; MD5=ae8598e9e42cb355130866aacbbaa539; length=1262; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0111689 type=protein; loc=2R:complement(join(24778875..24779813,24778699..24778816,24778344..24778627,24778035..24778290,24777467..24777972,24776647..24777408,24775859..24776575,24775594..24775800)); ID=FBpp0111689; name=egg-PA; parent=FBgn0086908,FBtr0112777; dbxref=GB_protein:AAM70794,FlyBase:FBpp0072337,GB_protein:AAF47268.2,GB_protein:AAM70794.1,FlyBase:FBpp0111689,GB_protein:AAF47268,FlyBase:FBpp0072336,FlyBase_Annotation_IDs:CG12196-PA,FlyBase_Annotation_IDs:CG30422-PA,FlyBase_Annotation_IDs:CG30426-PA,REFSEQ:NP_611966,GB_protein:AAF47268,FlyMine:FBpp0111689,modMine:FBpp0111689; MD5=ae8598e9e42cb355130866aacbbaa539; length=1262; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2R:complement(join(24778875..24779813,24778699..24778816,24778344..24778627,24778035..24778290,24777467..24777972,24776647..24777408,24775859..24776575,24775594..24775800)); ID=FBpp0111689; name=egg-PA; parent=FBgn0086908,FBtr0112777; dbxref=GB_protein:AAM70794,FlyBase:FBpp0072337,GB_protein:AAF47268.2,GB_protein:AAM70794.1,FlyBase:FBpp0111689,GB_protein:AAF47268,FlyBase:FBpp0072336,FlyBase_Annotation_IDs:CG12196-PA,FlyBase_Annotation_IDs:CG30422-PA,FlyBase_Annotation_IDs:CG30426-PA,REFSEQ:NP_611966,GB_protein:AAF47268,UniProt/Swiss-Prot:Q32KD2,FlyMine:FBpp0111689,modMine:FBpp0111689; MD5=ae8598e9e42cb355130866aacbbaa539; length=1262; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1262 amino acids
Gene Ontology:
Cellular Component:	polytene chromosome [IDA] nucleus [IDA] cytoplasm [IDA] chromocenter [IDA]
Biological Process:	wing disc development [IMP] oogenesis [IMP] histone methylation [IMP] instar larval or pupal development [IMP] histone H3-K9 methylation [IDA][IMP] regulation of gene expression, epigenetic [IMP]
Molecular Function:	DNA binding [IEA] zinc ion binding [IEA] protein binding [IPI] histone methyltransferase activity (H3-K9 specific) [IDA][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGQPTAVDC LESSGSTVED VQETPASREK SYGLPVRKGE NSLESPAEQA AKDVEIEELT  60
   61 HSEAIAATGS TRKQCPYGGK APDEPGKLAD ESEDRKGENT KAIASSPVLV AVDSDSSVEL 120
  121 IESPVKFSSA NESEKDPPKP DAVNEAAAKE AEEMTDSSIS SPTSESFPEK DEKTNKENEQ 180
  181 EPPGMEVDQD VEESISRPAE EYKIENTLKG HKRISLTEIE EHKIVDKKDD VLEVELEKGT 240
  241 APKAAEDEKL NALLSDGDVF YDKECVNCNC TKLHKQYVLA NMATLNFYQV LRKSSKQQFL 300
  301 CMGCHDTAMD LYEEYAGQLM AKQPLLLKDF HQDHADFVAL DSSDEEEEEK QPEKSDFSKN 360
  361 KLQLIEDELD DAIKNVLNKV DFTAQLSWSK TILQAKADHL ERQFALADVE LEKVQTTADK 420
  421 MHCALYNSCP VAHKHLPTLD IEPSDYVHEV PPPGEIVRPP IQLGETYYAV KNKAIASWVS 480
  481 IKVIEFTEST AINGNTMKSY KIRYLNTPYQ MIKTVTAKHI AYFEPPPVRL TIGTRVIAYF 540
  541 DGTTLSRGKD KGVVQSAFYP GIIAEPLKQA NRYRYLIFYD DGYTQYVPHR DVRLVCQASE 600
  601 KVWEDVHAAS RDFIQKYVEK YSVDRPMVQC TRGQSMTTES NGTWLYARVI DIDCSLVLMQ 660
  661 FEGDKNHTEW IYRGSLRLGP VFRETQNNMN SSSAQQLRVP RRTEPFIRYT KEMESSSKVN 720
  721 QQMRAFARKS SASAQNNALA AASSAATPAG GRTNAGGVST SNSASAVRHL NNSTIYVDDE 780
  781 NRPKGHVVYF TAKRNLPPKM YKCHECSPNC LFKIVHRLDS YSPLAKPLLS GWERLVMRQK 840
  841 TKKSVVYKGP CGKSLRSLAE VHRYLRATEN VLNVDNFDFT PDLKCLAEYS IDPSIVKDTD 900
  901 ISKGQEKMAI PLVNYYDNTL PPPCTYAKQR IPTEGVHLNL DEEFLLCCDC EDDCSDKSKC 960
  961 ACWQLTVAGV RYCNPKKPIE EIGYQYKRLH EHVPTGIYEC NSRCKCKKNC LNRVVQFSLE1020
 1021 MKLQVFKTSN RGWGLRCVND IPKGAFICIY AGHLLTETMA NEGGQDAGDE YFADLDYIEV1080
 1081 AEQLKEGYES EVDHSDPDAE EDNGGPDAED DDDFRPNYHY QRKIKRSSRS GSTQNSSTQS1140
 1141 SELDSQERAV INFNPNADLD ETVRENSVRR LFGKDEAPYI MDAKTTGNLG RYFNHSCSPN1200
 1201 LFVQNVFVDT HDLRFPWVAF FSAAHIRSGT ELTWNYNYEV GVVPGKVLYC QCGAPNCRLR1260
 1261 LL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: egg-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: