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Protein Overview: ent-3

General Information:
Name(s) found: ent-3 / CE37978 [WormBase]
Description(s) found:
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  • WBGene00010510 locus:ent-3 status:Partially_confirmed UniProt:Q21145 protein_id:CAB01223.2 [WormBase]
  • gi|71997684|ref|NP_506521.2| Equilibrative Nucleoside Transporter family member (ent-3) [Caenorhabditis elegans] [NCBI NR]
  • gi|58081854|emb|CAB01223.2| C. elegans protein K02E11.1, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • CE37978 WBGene00010510 locus:ent-3 status:Partially_confirmed TR:Q21145 protein_id:CAB01223.2 [wormpep150.fasta]
  • 37978 WBGene00010510 locus:ent-3 status:Partially_confirmed TR:Q21145 protein_id:CAB01223.2 [wormpep150-phg-orf-ecoli-rand.fasta]
  • CE37978 WBGene00010510 locus:ent-3 status:Partially_confirmed UniProt:Q21145_CAEEL protein_id:CAB01223.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE37978 WBGene00010510 locus:ent-3 status:Partially_confirmed UniProt:Q21145_CAEEL protein_id:CAB01223.2| [wormORF-contam.fasta]
  • Equilibrative Nucleoside Transporter family member (ent-3) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein K02E11.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE37978 WBGene00010510 locus:ent-3 status:Partially_confirmed UniProt:Q21145 protein_id:CAB01223.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • Equilibrative Nucleoside Transporter OS=Caenorhabditis elegans GN=ent-3 PE=4 SV=2 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 729 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: transport [IEALink to PubMed article]
    Molecular Function: nucleoside transmembrane transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSTKDRQAL CKKCKKGIAT KSSRASKRLR SSKSTRSRKS VKPSKSNKKA ENEKKRQVLR  60
   61 NWITRKRREF NNEDSSSQTT SKIPKRAILF CVMTDTVKEK SALCAIIATK RKRTKKNNKP 120
  121 IQIIAELRMS TKFHFKRVFE IVEKMCREQG IDDIDDHSYL LEVKSVNAFE GNSFSLAAGI 180
  181 ALYAVCSGTT VKNETIVIGK LDKTGNIEWD EYAEEEVKHA IKHNFQQVLM PFTNLPHVSE 240
  241 EHKQAIDCNG IRTFKDALEL MVVHPSSMQR HNAGADDVST NDYDTFVEKS VKHTKSPESI 300
  301 ESGSITDQNI TDTDEVKDLG NYVFFIFMMF GFGALLPWNM FLNISFDYYT MFKLRSADGN 360
  361 ATWYSSNFQN SMTISAQIPS LVFSVINIFI AVKGDLTRGM KICLIVVQLM VIVTVVFIYI 420
  421 DTSTWIATFS MLTLGTIVVL NAANGLFQNS MFGLASPFPF KYTNAVIIGQ NFCGTAVTVL 480
  481 SMLTKAASDD VQMRASLFFG LSSVAVVVCF ILLNFLKRLA FYKKFGILRT SSQSDEEGIS 540
  541 SWESVKLAFE KSKMQFANIF VLFFVTLALF PNVCMYVKDA KKGELHSFVV PEKYFMDVVT 600
  601 FLNFNLFAFL GSLMANWIRF PGPNTVWICV AARFWFMFYF PAANYHPMDF PRAYPVLFES 660
  661 TWLFAFNICI FALTSGYLSS LIMMYAPRSH EDPKIQRMAG MIASFFLIFG IVAGLVFSWQ 720
  721 IRLFMTGYA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..93] deduced N/A No confident structure predictions are available.
    2 View Details [94..271] PSI-BLAST 58.39794 Catalytic domain of E.coli Lon protease
    3 View Details [272..729] PSI-BLAST 39.0 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.06355800505512 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.804251312253629 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.75307991342421 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.728838449772752 bayes_pls_golite062009
  • nuclease activity
    		•  0.69721312877891 bayes_pls_golite062009
  • structural molecule activity
    		•  0.653141443225757 bayes_pls_golite062009
  • ATPase activity
    		•  0.652243617710716 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.608970207047375 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.540936026536059 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.523648791725881 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.520758768874988 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.506031376391446 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  0.48105441429954 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.477960254167 bayes_pls_golite062009
  • DNA binding
    		•  0.413758080397896 bayes_pls_golite062009
  • hydrolase activity
    		•  0.405362480272149 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  0.392367832041496 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.36703663415044 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.350394896843651 bayes_pls_golite062009
  • protein binding
    		•  0.214066724623027 bayes_pls_golite062009
    3
    Term Confidence Notes
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • binding
    		•  1.45862166005114 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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