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Protein Overview: nas-33

General Information:
Name(s) found: nas-33 / CE40705 [WormBase]
Description(s) found:
Found 12 descriptions.
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  • WBGene00003551 locus:nas-33 Zinc metalloproteinase nas-33 status:Partially_confirmed UniProt:P55114 protein_id:CCD64584.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 644 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: proteolysis [IEALink to PubMed article]
    Molecular Function: meprin A activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    astacin activity [IEALink to PubMed article]
    metallopeptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLFVSILISQ FVTCLTQPDF FERPPPPDWF FPGPLRPWGP PPPWHRNRGP PPFGPPPPWD  60
   61 RPPPPWRRPP WHRRPPWGLP PPPPPPEPEP QQDQPQVMFS QDIDKVVNSV NQNTAAFQRP 120
  121 GESYDKVIQI MSSYFNRKSG SQYDINTVIP SSGIYNNEMA ANSKIAAVMF ESDMALTVSQ 180
  181 MNKVAQNGFR VKRKMNLNGT TWSRNIPYRF LDTDGNWQSQ ITNGLRHYER NTCIRFSLNG 240
  241 GGSDYLVFSK GEGCYSSVGR LGGPQEISIG DGCETLGIIT HEVGHALGFW HEQARPERDS 300
  301 YVRINRQNAI NGLEGQFDKR SWSEVNEYSL PYDYGSVMHY GPKSFSKSST MNTVEPVDPA 360
  361 FINTIGNRVE PSFLDLKLLN TAFCSNICTN RINCQHGGYA DPNNCGQCTC PTGLEGTYCE 420
  421 RLQTSNCGVE LPRADYSWRN ISYSGSSDCY WRIVSANGGN VRFELTYVMY RCSPVCEEFV 480
  481 EMKAEYSHEA TGYRQCCKAV LGERISKGNS VLIISKATQN SQFVLRYRED GTAPTQRPPP 540
  541 VRVAAPRSYS LLWSGWTRCS ENCGSCGTQY RERCTSTTNC LRSAKQTRVC NTQPCAQGTT 600
  601 RGKRSVLQTQ ISHRVKRLNG WCCARFVLSR GVCVPVRTGV THPN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..190] FFAS03 0.954 No description for 2j63A was found.
    2 View Details [191..370] PSI-BLAST 53.39794 STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
    3 View Details [371..644] PSI-BLAST 16.30103 Solution structure of dimeric form of properdin by X-ray solution scattering and analytical ultracentrifugation

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • peptidase activity
    		•  3.87713655504947 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  3.50720289959102 bayes_pls_golite062009
  • metallopeptidase activity
    		•  2.55317823694462 bayes_pls_golite062009
  • endopeptidase activity
    		•  2.52973705827479 bayes_pls_golite062009
  • hydrolase activity
    		•  2.30803642767787 bayes_pls_golite062009
  • metalloendopeptidase activity
    		•  1.81132179546381 bayes_pls_golite062009
  • catalytic activity
    		•  1.26162753036584 bayes_pls_golite062009
  • exopeptidase activity
    		•  0.71491631246151 bayes_pls_golite062009
  • binding
    		•  0.210557818016724 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.52

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle