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Protein Overview: gi|481953, gi|438212

General Information:
Name(s) found: gi|481953 [NCBI NR]
gi|438212 [NCBI NR]
Description(s) found:
Found 4 descriptions.
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  • pir||S40259 glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) - malaria parasite (Plasmodium falciparum) [NCBI NR]
  • gi|438212|emb|CAA52921.1| glucose-6-phosphate 1-dehydrogenase [Plasmodium falciparum] [NCBI NR]
    • Organism: Plasmodium falciparum
    Length: 910 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: pentose-phosphate shunt [TASLink to PubMed article]
    Molecular Function: 6-phosphogluconolactonase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYENFVKSA EEINNLHNVN YLETKDLNDF NWKAAYYICK EIYDKQQINK DGYVVIGLSG  60
   61 GRTPIDVYKN MCLIKDIKID KSKLIFFIID ERYKSDDHKF SNYNNIKFLF HNLNINEKEQ 120
  121 LYKPDTTKSI VDCILDYNDK IKIMIEKYKK VDIAILGMGS DFHIASLFPN IFYNIYMNNY 180
  181 QNNYIYNEKT LDFINNDQDN DNLKYLKEYV YFTTTNQFDV RKRITVSLNL LANASSKIFL 240
  241 LNSKDKLDLW KNMLIKSYIE VNYNLYPATY LIDTSCTNEN VNINNNNNNN NKNKNNYCYS 300
  301 NTTVISCGYE NYTKSIEEIY DSKYALSLYS NSLNKEELLT IIIFGCSGDL AKKKIYPALF 360
  361 KLFCNNSLPK DLLIIGFART VQDFDTFFDK IVIYLKRCLL CYEDWSISKK KDLLNGFKNR 420
  421 CRYFVGNYSS SESFENFNKY LTTIEEEEAK KKYYATCYKM NGSDYNISNN VAEDNISIDD 480
  481 ENKTNEYFQM CTPKNCPDNV FSSNYNFPYV INRMLYLALP PHIFVSTLKN YKKNCLNSKG 540
  541 TDKILLEKPF GNDLDSFKML SKQILENFNE QQIYRIDHYL GKDMVSGLLK LKFTNTFLLS 600
  601 LMNRHFIKCI KITLKETKGV YGRGQYFDPY GIIRDVMQNH MLQLLTLITM EDPIDLNDES 660
  661 VKNEKIKILK SIPSIKLEDT IIGQYEKAEN FKEDENNDDE SKKNHSYHDD PHIDKNSITP 720
  721 TFCTCILYIN SINWYGVPII FKSGKGLNKD ICEIRIQFHN IMGSSDENMN NNEFVIILQP 780
  781 VEAIYLKMMI KKTGCEEMEE VQLNLTVNEK NKKINVPEAY ETLLLECFKG HKKKFISDEE 840
  841 LYESWRIFTP LLKELQEKQV KPLKYSFGSS GPKEVFGLVK KYYNYGKNYT HRPEFVRKSS 900
  901 FYEDDLLDIN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..297] PSI-BLAST 64.221849 HUMAN GLUCOSAMINE-6-PHOSPHATE DEAMINASE ISOMERASE AT 1.75 A RESOLUTION COMPLEXED WITH N-ACETYL-GLUCOSAMINE-6-PHOSPHATE AND 2-DEOXY-2-AMINO-GLUCITOL-6-PHOSPHATE
    2 View Details [298..910] PSI-BLAST 1000.0 Glucose 6-phosphate dehydrogenase, N-terminal domain; Glucose 6-phosphate dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ribose-5-phosphate isomerase activity
    		•  2.9184163250889 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting aldoses and ketoses
    		•  2.10773292255613 bayes_pls_golite062009
  • catalytic activity
    		•  1.68776709414398 bayes_pls_golite062009
  • transferase activity, transferring sulfur-containing groups
    		•  1.65060457499831 bayes_pls_golite062009
  • intramolecular oxidoreductase activity
    		•  1.63493703669467 bayes_pls_golite062009
  • 6-phosphogluconolactonase activity
    		•  1.1599825493677 bayes_pls_golite062009
  • isomerase activity
    		•  0.61588631681492 bayes_pls_golite062009
  • binding
    		•  9.84508048393007E-4 bayes_pls_golite062009
    2
    Term Confidence Notes
  • glucose-6-phosphate dehydrogenase activity
    		•  2.90814647084155 bayes_pls_golite062009
  • catalytic activity
    		•  2.16785883389468 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.3919444853018 bayes_pls_golite062009
  • glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity
    		•  1.37368669593547 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.27605103494323 bayes_pls_golite062009
  • aspartate-semialdehyde dehydrogenase activity
    		•  1.23689472371927 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  0.241113029381333 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  0.240794684270136 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle