Protein Overview: HDAC3_RAT

General Information:
Name(s) found:	HDAC3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|81885290\|sp\|Q6P6W3.1\|HDAC3_RAT RecName: Full=Histone deacetylase 3; Short=HD3 [NCBI NR] gi\|38541400\|gb\|AAH61988.1\| Hdac3 protein [Rattus norvegicus] [NCBI NR] gi\|149017368\|gb\|EDL76419.1\| histone deacetylase 3, isoform CRA_c [Rattus norvegicus] [NCBI NR] gi\|149017364\|gb\|EDL76415.1\| histone deacetylase 3, isoform CRA_c [Rattus norvegicus] [NCBI NR] Histone deacetylase 3 OS=Rattus norvegicus GN=Hdac3 PE=1 SV=1 [Swiss-Prot] Hdac3 protein [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Hdac3 protein [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Histone deacetylase 3 (HD3) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] histone deacetylase 3, isoform CRA_c [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 HDAC3 PROTEIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Hdac3 Histone deacetylase 3 [rat-ipi-250309-contam.fasta] Histone deacetylase 3 OS=Rattus norvegicus GN=Hdac3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	428 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA] spindle microtubule [UNKNOWN][IEA] cytoplasm [IDA] transcriptional repressor complex [UNKNOWN][IEA] chromatin [IDA] nucleoplasm [UNKNOWN]
Biological Process:	chromatin modification [IEA] regulation of multicellular organism growth [UNKNOWN][IEA] negative regulation of cell cycle [UNKNOWN] protein amino acid deacetylation [UNKNOWN] regulation of transcription [IEA] negative regulation of JNK cascade [UNKNOWN][IEA] regulation of mitotic cell cycle [UNKNOWN][IEA] spindle assembly [UNKNOWN][IEA] circadian regulation of gene expression [UNKNOWN][IEA] response to drug [IEP] [NOT]negative regulation of myotube differentiation [UNKNOWN] histone deacetylation [UNKNOWN][IEA] negative regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN][IEA]
Molecular Function:	DNA binding [UNKNOWN][IEA] protein binding [UNKNOWN][IEA] histone deacetylase activity [UNKNOWN][IEA] histone deacetylase binding [UNKNOWN][IEA] transcription corepressor activity [UNKNOWN][IEA] chromatin binding [UNKNOWN][IEA] promoter binding [IEA] protein deacetylase activity [UNKNOWN] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKTVAYFYD PDVGNFHYGA GHPMKPHRLA LTHSLVLHYG LYKKMIVFKP YQASQHDMCR  60
   61 FHSEDYIDFL QRVSPTNMQG FTKSLNAFNV GDDCPVFPGL FEFCSRYTGA SLQGATQLNN 120
  121 KICDIAINWA GGLHHAKKFE ASGFCYVNDI VIGILELLKY HPRVLYIDID IHHGDGVQEA 180
  181 FYLTDRVMTV SFHKYGNYFF PGTGDMYEVG AESGRYYCLN VPLRDGIDDQ SYKHLFQPVI 240
  241 SQVVDFYQPT CIVLQCGADS LGCDRLGCFN LSIRGHGECV EYVKSFNIPL LVLGGGGYTV 300
  301 RNVARCWTYE TSLLVEEAIS EELPYSEYFE YFAPDFTLHP DVSTRIENQN SRQYLDQIRQ 360
  361 TIFENLKMLN HAPSVQIHDV PADLLTYDRT DEADAEERGP EENYSRPEAP NEFYDGDHDN 420
  421 DKESDVEI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: HDAC3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: