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Protein Overview: gi|4688975

General Information:
Name(s) found: gi|4688975 [NCBI NR]
Description(s) found:
Found 3 descriptions.
SHOW ALL
  • gi|4688975|emb|CAB41452.1| IRP-like protein (iron regulatory protein-like) [Plasmodium falciparum] [NCBI NR]
    • Organism: Plasmodium falciparum
    Length: 909 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: tricarboxylic acid cycle [ISSLink to PubMed article]
    regulation of translational initiation by iron [ISSLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHFRRCIRKY CINKKIVNPF EHVQRTLNEK NYYYYDINEL HDSRIKSLPY SIRVLLESAV  60
   61 RNCDNLKVSE KNVETILGWK ENCKKKKEVP FMPTRVLLQD LTGVPCIVDL ATMRDTAEKL 120
  121 GCDAERINPL IPVDLVIDHS VQVDYSRRED ALELNEKKEY ERNLERFKFL KWGMNSFKNM 180
  181 LILPPGSGIV HQINLEYLAH CVFNKDNLLY PDSVVGTDSH TTMINGLGIL GWGVGGIEAE 240
  241 ATMLGLPISM TLPEVVGINV VGKLSDYLLS TDIVLYITSF LRKEVGVVNK YVEFFGTGLK 300
  301 DLKLADRATI SNMAPEYGAT VGFFPVDDIT LEYLLQTGRD KEKVELIREY LMKNSMFNTY 360
  361 KDNVEYTDVY TLDLSKLNLS LSGPKRPHDN VLLSELHKDF TMCLESPIGF KGYNIAKEER 420
  421 EKKISFVCSK DGKEYVLSQG SVVLCAITSC TNTSNSSSMI AAGLLAKKAI EEFGLKSLPY 480
  481 IKSSLSPGSK TVQKYLEAGG LLKYLEQLGF YNVGYGCMTC IGNSGHLDEE VEEVINKNDL 540
  541 IVSSVLSGNR NFEGRVHPLI KANYLASPVL VVLFSIIGNV NVDLSNYTFN YKGKKINALD 600
  601 LIPRKEEIEE YESTYIKPEM YTEIYKNIKY VNKYWNDIQI KKNKLYEWDK NSTYIHKPPY 660
  661 FENMTLEIEK IQDIKDAHVL LFLGDSITTD HISPAGMIHK TSEAYKFLKT KNIKDQDLNT 720
  721 YGARRGNDEV MIRGTFANIR LINKLCPDKG PNTIHIPTNQ LMSVYQAAMK YKQDNIDVII 780
  781 IAGKEYGCGS SRDWAAKGPN LLGVKAVIAE SYERIHRSNL IGMSVLPLQF INNQSPQYYN 840
  841 MDGTEKFTIL LNDGNIKAQQ TIKVQMNQKG KIIIFDVLCR IDTEIEERYF RNGGILKYVL 900
  901 RSLVNEANK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..909] PSI-BLAST 1000.0 Structure of an orthorhombic crystal form of human cytosolic aconitase (IRP1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3-isopropylmalate dehydratase activity
    		•  11.6597692115322 bayes_pls_golite062009
  • aconitate hydratase activity
    		•  5.86356477922338 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.93956285477489 bayes_pls_golite062009
  • catalytic activity
    		•  2.4040324437254 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.25736437672211 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  2.08349115784849 bayes_pls_golite062009
  • hydro-lyase activity
    		•  2.04845291489052 bayes_pls_golite062009
  • lyase activity
    		•  2.0080619912194 bayes_pls_golite062009
  • metal cluster binding
    		•  1.70706327499066 bayes_pls_golite062009
  • iron-sulfur cluster binding
    		•  1.70706327499066 bayes_pls_golite062009
  • binding
    		•  1.67914740974449 bayes_pls_golite062009
  • DNA binding
    		•  1.6436451615422 bayes_pls_golite062009
  • iron-responsive element binding
    		•  1.1980380564483 bayes_pls_golite062009
  • iron ion binding
    		•  1.12961684198784 bayes_pls_golite062009
  • 4 iron, 4 sulfur cluster binding
    		•  1.11810757572823 bayes_pls_golite062009
  • mRNA binding
    		•  1.0310744464034 bayes_pls_golite062009
  • structural molecule activity
    		•  0.870913754566634 bayes_pls_golite062009
  • RNA binding
    		•  0.42311333660604 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.342428816025605 bayes_pls_golite062009
  • protein binding
    		•  0.232638130896339 bayes_pls_golite062009
  • cation binding
    		•  0.0272064751959212 bayes_pls_golite062009
  • metal ion binding
    		•  0.0272064751959212 bayes_pls_golite062009
  • ion binding
    		•  0.0228992031160024 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle