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Protein Overview: ATCU_ECOLI

General Information:
Name(s) found: ATCU_ECOLI [Swiss-Prot]
Description(s) found:
Found 8 descriptions.
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  • Copper-transporting P-type ATPase (EC 3.6.3.4) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 834 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQTIDLTLD GLSCGHCVKR VKESLEQRPD VEQADVSITE AHVTGTASAE QLIETIKQAG  60
   61 YDASVSHPKA KPLAESSIPS EALTAVSEAL PAATADDDDS QQLLLSGMSC ASCVTRVQNA 120
  121 LQSVPGVTQA RVNLAERTAL VMGSASPQDL VQAVEKAGYG AEAIEDDAKR RERQQETAVA 180
  181 TMKRFRWQAI VALAVGIPVM VWGMIGDNMM VTADNRSLWL VIGLITLAVM VFAGGHFYRS 240
  241 AWKSLLNGAA TMDTLVALGT GVAWLYSMSV NLWPQWFPME ARHLYYEASA MIIGLINLGH 300
  301 MLEARARQRS SKALEKLLDL TPPTARLVTD EGEKSVPLAE VQPGMLLRLT TGDRVPVDGE 360
  361 ITQGEAWLDE AMLTGEPIPQ QKGEGDSVHA GTVVQDGSVL FRASAVGSHT TLSRIIRMVR 420
  421 QAQSSKPEIG QLADKISAVF VPVVVVIALV SAAIWYFFGP APQIVYTLVI ATTVLIIACP 480
  481 CALGLATPMS IISGVGRAAE FGVLVRDADA LQRASTLDTV VFDKTGTLTE GKPQVVAVKT 540
  541 FADVDEAQAL RLAAALEQGS SHPLARAILD KAGDMQLPQV NGFRTLRGLG VSGEAEGHAL 600
  601 LLGNQALLNE QQVGTKAIEA EITAQASQGA TPVLLAVDGK AVALLAVRDP LRSDSVAALQ 660
  661 RLHKAGYRLV MLTGDNPTTA NAIAKEAGID EVIAGVLPDG KAEAIKHLQS EGRQVAMVGD 720
  721 GINDAPALAQ ADVGIAMGGG SDVAIETAAI TLMRHSLMGV ADALAISRAT LHNMKQNLLG 780
  781 AFIYNSIGIP VAAGILWPFT GTLLNPVVAG AAMALSSITV VSNANRLLRF KPKE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..181] PSI-BLAST 24.154902 Structure characterization of the water soluble region of P-type ATPase CopA from Bacillus subtilis
    2 View Details [182..252] MSA 2.017995 View MSA. No confident structure predictions are available.
    3 View Details [253..834] PSI-BLAST 96.154902 Proton ATPase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • copper chaperone activity
    		•  9.82063669832995 bayes_pls_golite062009
  • copper-dependent protein binding
    		•  9.4886676850819 bayes_pls_golite062009
  • metallochaperone activity
    		•  8.74818422646376 bayes_pls_golite062009
  • superoxide dismutase copper chaperone activity
    		•  7.67724993505658 bayes_pls_golite062009
  • copper ion transmembrane transporter activity
    		•  6.91184156399207 bayes_pls_golite062009
  • copper ion binding
    		•  5.41725082570189 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  5.4007166857771 bayes_pls_golite062009
  • copper-exporting ATPase activity
    		•  5.04749761961029 bayes_pls_golite062009
  • copper-transporting ATPase activity
    		•  5.03252922496602 bayes_pls_golite062009
  • transition metal ion transmembrane transporter activity
    		•  4.79570221435856 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.61622753861072 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.52484959112186 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.12792340516867 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  4.10264569844449 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  3.70964017127302 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
    		•  3.27250923701445 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  2.98847682261773 bayes_pls_golite062009
  • metal ion binding
    		•  2.69806984896689 bayes_pls_golite062009
  • cation binding
    		•  2.69806984896689 bayes_pls_golite062009
  • ion binding
    		•  2.69078950610234 bayes_pls_golite062009
  • transition metal ion binding
    		•  2.52520930681159 bayes_pls_golite062009
  • transporter activity
    		•  2.43435890488191 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.32163502360862 bayes_pls_golite062009
  • binding
    		•  2.31155280022787 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.28845421748925 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  1.62116507842838 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  1.61680623728503 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  1.59572740343301 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  1.5925429451548 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  1.59219836319916 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.53883152283038 bayes_pls_golite062009
  • hydrolase activity
    		•  1.26149508477113 bayes_pls_golite062009
  • ATPase activity
    		•  1.12732384636594 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.1123150216263 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.04872000948037 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.03270166246194 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.02977205960797 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.02520458852568 bayes_pls_golite062009
  • protein binding
    		•  0.889287086236279 bayes_pls_golite062009
  • cation-transporting ATPase activity
    		•  0.75722873989123 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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