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Protein Overview: gi|30258882, gi|...

General Information:
Name(s) found: gi|30264237 [NCBI NR]
gi|30258882 [NCBI NR]
Description(s) found:
Found 4 descriptions.
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  • gi|30264237|ref|NP_846614.1| 3-methyl-2-oxobutanoate dehydrogenase, alpha subunit [Bacillus anthracis str. Ames] [NCBI NR]
  • gi|30258882|gb|AAP28100.1| 3-methyl-2-oxobutanoate dehydrogenase, alpha subunit [Bacillus anthracis str. Ames] [NCBI NR]
    • Organism: Bacillus anthracis str. Ames
    Length: 333 amino acids

    Gene Ontology:
    Cellular Component: 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex [ISSLink to PubMed article]
    Biological Process: branched chain family amino acid catabolic process [ISSLink to PubMed article]
    Molecular Function: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEVKEKRHE ELGLSDEQVL EMFRTMLLAR KIDERMWLLN RAGKIPFVIS CQGQEAAQVG  60
   61 AAFALDREKD YALPYYRDMG VVLAFGMTAK ELMLSGFAKA GDPNSGGRQM PGHFGQKKNR 120
  121 IVTGSSPVTT QVPHAVGIAL AGKMEKKDLV TFVTFGEGSS NQGDFHEGAN FAGVHKLPVI 180
  181 FMCENNKYAI SIPVEKQLAC KNVSDRAIGY GMPGYTVDGN DPLAVYKAVK EAADRGRRGE 240
  241 GPTLIETVSY RLTAHSSDDD DRVYRDKEEV EEAKKNDSIV TFAAYLKEVG VLTEESEKQM 300
  301 LDEIMHIVNE ATEYAENAPY AAPEDALKHV YAE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..333] PSI-BLAST 62.69897 branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8 in apo-form

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • pyruvate dehydrogenase activity
    		•  11.3856674722026 bayes_pls_golite062009
  • pyruvate dehydrogenase (acetyl-transferring) activity
    		•  11.0549577473177 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
    		•  10.8180381281695 bayes_pls_golite062009
  • 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity
    		•  7.00951713446616 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  4.89064211833637 bayes_pls_golite062009
  • acetolactate synthase activity
    		•  4.51986503762195 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  3.8269109174531 bayes_pls_golite062009
  • alpha-ketoacid dehydrogenase activity
    		•  2.61614462349133 bayes_pls_golite062009
  • catalytic activity
    		•  2.25537597692103 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.85833680148029 bayes_pls_golite062009
  • transketolase activity
    		•  1.53492491341322 bayes_pls_golite062009
  • transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
    		•  0.667418924427388 bayes_pls_golite062009
  • pyruvate decarboxylase activity
    		•  0.198062360371269 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle