Protein Overview: FBpp0311724, inv...

General Information:
Name(s) found:	FBpp0311724 [FlyBase] inv-PB / FBpp0087175 [FlyBase] inv-PD / FBpp0087174 [FlyBase]
Description(s) found: Found 53 descriptions. SHOW ALL	type=protein; loc=2R:join(7363481..7364774,7392434..7392439,7393574..7393734,7394154..7394423); ID=FBpp0311724; name=inv-PE; parent=FBgn0001269,FBtr0345673; dbxref=FlyBase:FBpp0311724,FlyBase_Annotation_IDs:CG17835-PE; MD5=246035cf4fc1c38c4eedd2aff7f7ad53; length=576; release=r5.56; species=Dmel; [FlyBase] The gene invected is referred to in FlyBase by the symbol Dmel\inv (CG17835, FBgn0001269). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7361970..7394688. It has the cytological map location 47F15-47F17. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: neuroblast fate determination; compartment specification. 37 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; thoracic segment; adult; cuticle; multi-cell-component structure; embryonic hindgut; embryonic nervous system; nervous system; region of integument; developing anatomical structure. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene invected is referred to in FlyBase by the symbol Dmel\inv (CG17835, FBgn0001269). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7361970..7394688. It has the cytological map location 47F15-47F17. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: neuroblast fate determination; compartment specification. 37 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; adult segment; adult mesothoracic segment; thoracic segment; adult; cuticle; multi-cell-component structure; embryonic hindgut; embryonic nervous system; nervous system; region of integument; developing anatomical structure. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	576 amino acids
Gene Ontology:
Cellular Component:	nucleus [ISS][NAS]
Biological Process:	wing disc anterior/posterior pattern formation [TAS] neuroblast fate determination [IGI] regulation of transcription, DNA-dependent [IEA] compartment pattern formation [IMP][ISS][TAS] regulation of transcription [IEA] regulation of transcription from RNA polymerase II promoter [ISS]
Molecular Function:	transcription factor activity [IEA] RNA polymerase II transcription factor activity [ISS] sequence-specific DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTLASTRPP PLKLTIPSLE EAEDHAQERR AGGGGQEVGK MHPDCLPLPL VQPGNSPQVR  60
   61 EEEEDEQTEC EEQLNIEDEE VEEEHDLDLE DPASCCSENS VLSVGQEQSE AAQAALSAQA 120
  121 QARQRLLISQ IYRPSAFSST ATTVLPPSEG PPFSPEDLLQ LPPSTGTFQE EFLRKSQLYA 180
  181 EELMKQQMHL MAAARVNALT AAAAGKQLQM AMAAAAVATV PSGQDALAQL TATALGLGPG 240
  241 GAVHPHQQLL LQRDQVHHHH HMQNHLNNNE NLHERALKFS IDNILKADFG SRLPKIGALS 300
  301 GNIGGGSVSG SSTGSSKNSG NTNGNRSPLK APKKSGKPLN LAQSNAAANS SLSFSSSLAN 360
  361 ICSNSNDSNS TATSSSTTNT SGAPVDLVKS PPPAAGAGAT GASGKSGEDS GTPIVWPAWV 420
  421 YCTRYSDRPS SGRSPRARKP KKPATSSSAA GGGGGGVEKG EAADGGGVPE DKRPRTAFSG 480
  481 TQLARLKHEF NENRYLTEKR RQQLSGELGL NEAQIKIWFQ NKRAKLKKSS GTKNPLALQL 540
  541 MAQGLYNHST IPLTREEEEL QELQEAASAA AAKEPC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..107]	deduced	N/A	No confident structure predictions are available.
2	View Details	[108..282]	MSA	7.228997	View MSA. No confident structure predictions are available.
3	View Details	[283..473]	deduced	N/A	No confident structure predictions are available.
4	View Details	[474..576]	PSI-BLAST	22.522879	DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: FBpp0311724, inv...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: