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Protein Overview: unc-89

General Information:
Name(s) found: unc-89 / CE37702 [WormBase]
Description(s) found:
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  • WBGene00006820 locus:unc-89 Muscle M-line assembly protein unc-89 status:Partially_confirmed UniProt:O01761 protein_id:CCD63868.1 [WormBase]
  • gi|71980598|ref|NP_001020988.1| UNCoordinated family member (unc-89) [Caenorhabditis elegans] [NCBI NR]
  • gi|54607252|gb|AAV34799.1| Uncoordinated protein 89, isoform e, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • Uncoordinated protein 89, isoform e [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE37702 WBGene00006820 locus:unc-89 status:Partially_confirmed SW:O01761 protein_id:AAV34799.1 [wormpep150.fasta]
  • 37702 WBGene00006820 locus:unc-89 status:Partially_confirmed SW:O01761 protein_id:AAV34799.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • CE37702 WBGene00006820 locus:unc-89 status:Partially_confirmed [WormBase_C-elegans_na_01-20-2005_combined_reversed.fasta]
  • CE37702 WBGene00006820 locus:unc-89 status:Partially_confirmed UniProt:UNC89_CAEEL protein_id:AAV34799.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE37702 WBGene00006820 locus:unc-89 status:Partially_confirmed UniProt:UNC89_CAEEL protein_id:AAV34799.1| [wormORF-contam.fasta]
  • UNCoordinated family member (unc-89) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE37702 WBGene00006820 locus:unc-89 status:Partially_confirmed UniProt:O01761 protein_id:AAV34799.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE37702 WBGene00006820 locus:unc-89 status:Partially_confirmed UniProt:O01761 protein_id:CCD63868.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE37702 WBGene00006820 locus:unc-89 status:Partially_confirmed UniProt:O01761 protein_id:CCD63868.1 Muscle M-line assembly protein unc-89 [wormpep246-ecoli-contam.fasta]
  • Isoform of O01761, Isoform e of Muscle M-line assembly protein unc-89 OS=Caenorhabditis elegans GN=unc-89 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 5992 amino acids

    Gene Ontology:
    Cellular Component: A band [IDALink to PubMed article]
    extracellular region [IEALink to PubMed article]
    intracellular [IEALink to PubMed article]
    proteinaceous extracellular matrix [IEALink to PubMed article]
    Biological Process: regulation of Rho protein signal transduction [IEALink to PubMed article]
    carbohydrate metabolic process [IEALink to PubMed article]
    DNA repair [IEALink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    regulation of cell growth [IEALink to PubMed article]
    protein amino acid dephosphorylation [IEALink to PubMed article]
    cell adhesion [IEALink to PubMed article]
    blood coagulation [IEALink to PubMed article]
    protein amino acid phosphorylation [IEALink to PubMed article]
    Molecular Function: magnesium ion binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    protein tyrosine kinase activity [IEALink to PubMed article]
    protein tyrosine phosphatase activity [IEALink to PubMed article]
    protein kinase activity [IEALink to PubMed article]
    Rho guanyl-nucleotide exchange factor activity [IEALink to PubMed article]
    protein serine/threonine kinase activity [IEALink to PubMed article]
    insulin-like growth factor binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASRRQKQFD RKYSSYRKFT ATEDVNYSTH SSRSSYRSES LTSRTDGRGR STSSEIIAGS  60
   61 ESRSYPVYIA IQDYTPDKED VEAIPLEQGQ IVEVLDKKNS VRWLVRTKAR PPRSGWVPGS 120
  121 YFETPTEFYK QRRRTREIEN VSLSDEQAAL VKRDQVYHEL LRSEEEFVSS LRTCVDDYIK 180
  181 VLDDPEVPEA VKKNREELTL NIPELYNFHA NVMLKGLNYY SDDPGKVGQT FVRLEKDFES 240
  241 HVEFYKQYAD TLKLLEEPEI KRFFEGLSAK NDAGASSFVD HVKEIADRMV QYQNYFKEFV 300
  301 KYSARAHGSS KSIQKALELV TTIPQRVHDL EFTNNLKQHP GDTGKLGRII RHDAFQVWEG 360
  361 DEPPKLRYVF LFRNKIMFTE QDASTSPPSY THYSSIRLDK YNIRQHTTDE DTIVLQPQEP 420
  421 GLPSFRIKPK DFETSEYVRK AWLRDIAEEQ EKYAAERDAI SMTATSEMTA SSVDFDMNAS 480
  481 DQQSEFSEWS GSRKSSLFPG PEEGGPPRKK VKSPPVISPT GSSTSIYSGG SSSIDWTTTG 540
  541 TTLEMQGTRV TRTQYGFRTL QESSAKMCLK VTGYPLPDIT WYKDDVQLHE DERHTFYSDE 600
  601 DGFFAMTIDP VQVTDTGRYT CMATNEYGQA STSAFFRVLK VEKEAAPPAF VTKLRDKECK 660
  661 EGDVIDFECE VEGWPEPELV WLVDDQPLRP SHDFRLQYDG QTAKLEIRDA QPDDTGVYTV 720
  721 KIQNEFGSIE SKAELFVQAD PDKNHVAPEF QATIEYVECD EGEEVRFKSV ITGDPNPEII 780
  781 WFINGKPLSE SEKVKFISED GICILTIKDV TRHFDGMVTC QGSNRLGSAS CDGRLKVRVP 840
  841 PAPPTFNKPL EDKTVQEKST VVFEVDVSGW PEPTLTFTLC GKELKNGEEG VEIVGHDGFY 900
  901 RISIPNTSMD KHDGEIVAKA QNEHGTAESR ARLTVEQEEE ESRSAPTFLK DIEDQTVKTG 960
  961 EFAVFETTVR GNPNPEVTWF INGHKMDQGS PGVKIEAHNH DHKLTIDSAQ YAGTVLCRAE1020
 1021 NAVGRFETKA RLVVLAPEKQ KKPPKFVEIL VDKTETVDNT VVFEVRVEGE PKPTVTWYLK1080
 1081 GEELKQSDRV EIREFDGSIK ISIKNIKIED AGEIRAVATN SEGSDETKAK LTVQKKPFAP1140
 1141 EFDLRPVSLT VEKGSEAVFS AHAFGIPLPT YEWSVNGRKV RDGQEGARVT RDESTVDGAS1200
 1201 ILTIDTATYY SEVNHLTISV VAENTLGAEE TGAQLTIEPK KPPAPKLTRD LKLQTVNKTD1260
 1261 LAHFEVVVEH ATECKWFLDG KEITTAQGVT VSKDDQFEFR CSIDTTMFGS GTVSVVASNA1320
 1321 AGSVETKTEL KVLETPKETK KPEFTDKLRD MEVTKGDTVQ MDVIALHSPL YKWYQNGNLL1380
 1381 EDGKNGVTIK NEENKSSLII PNAQDSGKIT VEASNEVGSS ESSAQLTVNP PSTTPIVVDG1440
 1441 PKSVTIKETE TAEFKATISG FPAPTVKWTI NEKIVEESRT ITTIKTEDVY TLKISNAKIE1500
 1501 QTGTVKVTAQ NSAGQDSKQA DLKVEPNVKA PKFKSQLTDK VADEGEPLRW NLELDGPSPG1560
 1561 TEVSWLLNGQ PLTKSDTVQV VDHGDGTYHV TIAEAKPEMS GTLTAKAKNA AGECETSAKV1620
 1621 TVNGGNKKPE FVQAPQNHET TLEESVKFSA IVTGKPMPNV TWYLNNKKLI QSEEVKVKYV1680
 1681 HETGKTSIRI QKPLMEHNGT IRVEAENVSG KVQATAQLKV DKKTEVPKFT TNMDDRQVKE1740
 1741 GEDVKFTANV EGYPEPSVAW TLNGEPVSKH PNITVTDKDG EHTIEISAVT PEQAGELSCE1800
 1801 ATNPVGSKKR DVQLAVKKVG DAPTFAKNLE DRLITEGELT LMDAKLNIVK PKPKITWLKD1860
 1861 GVEITSDGHY KIVEEEDGSL KLSILQTKLE DKGRITIKAE SEFGVAECSA SLGVVKGRPM1920
 1921 AKPAFQSDIA PINLTEGDTL ECKLLITGDP TPFVKWYIGT QLVCATEDTE ISNANGVYTM1980
 1981 KIHGVTADMT GKIKCVAYNK AGEVSTEGPL KVVAPIPVEF ETSLCDATCR EGDTLKLRAV2040
 2041 LLGEPEPVVS WYVNGKKLEE SQNIKIHSEK GTYTVTIKDI TCDYSGQVVC EAINEYGKAT2100
 2101 SEATLLVLPR GEPPDFLEWL SNVRARTGTK VVHKVVFTGD PKPSLTWYIN NKEILNSDLY2160
 2161 TIVTDDKTST LTINSFNPDV HVGEIICKAE NDAGEVSCTA NMITYTSDMF SESESEAQAE2220
 2221 EFVGDDLTED ESLREEMHRT PTPVMAPKFI TKIKDTKAKK GHSAVFECVV PDTKGVCCKW2280
 2281 LKDGKEIELI ARIRVQTRTG PEGHITQELV LDNVTPEDAG KYTCIVENTA GKDTCEATLT2340
 2341 VIESLEKKSE KKAPEFIVAL QDKTTKTSEK VVLECKVIGE PKPKVSWLHD NKTITQESIT2400
 2401 VESVEGVERV TITSSELSHQ GKYTCIAENT EGTSKTEAFL TVQGEAPVFT KELQNKELSI2460
 2461 GEKLVLSCSV KGSPQPHVDF YSFSETTKVE TKITSSSRIA IEHDQTNTHW RMVISQITKE2520
 2521 DIVSYKAIAT NSIGTATSTS KITTKVEAPV FEQGLKKTSV KEKEEIKMEV KVGGSAPDVE2580
 2581 WFKDDKPVSE DGNHEMKKNP ETGVFTLVVK QAATTDAGKY TAKASNPAGT AESSAEAEVT2640
 2641 QSLEKPTFVR ELVTTEVKIN ETATLSVTVK GVPDPSVEWL KDGQPVQTDS SHVIAKVEGS2700
 2701 GSYSITIKDA RLEDSGKYAC RATNPAGEAK TEANFAVVKN LVPPEFVEKL SPLEVKEKES2760
 2761 TTLSVKVVGT PEPSVEWFKD DTPISIDNVH VIQKQTAVGS FSLTINDARQ GDVGIYSCRA2820
 2821 RNEAGEALTT ANFGIIRDSI PPEFTQKLRP LEVREQETLD LKVTVIGTPV PNVEWFKDDK2880
 2881 PINIDNSHIF AKDEGSGHHT LTIKQARGED VGVYTCKATN EAGEAKTTAN MAVQEEIEAP2940
 2941 LFVQGLKPYE VEQGKPAELV VRVEGKPEPE VKWFKDGVPI AIDNQHVIEK KGENGSHTLV3000
 3001 IKDTNNADFG KYTCQATNKA GKDETVGELK IPKYSFEKQT AEEVKPLFIE PLKETFAVEG3060
 3061 DTVVLECKVN KESHPQIKFF KNDQPVEIGQ HMQLEVLEDG NIKLTIQNAK KEDVGAYRCE3120
 3121 AVNVAGKANT NADLKIQFAA KVEEHVTDES GQLEEIGQFE TVGDTASSKT DTGRGAPEFV3180
 3181 ELLRSCTVTE KQQAILKCKV KGEPRPKIKW TKEGKEVEMS ARVRAEHKDD GTLTLTFDNV3240
 3241 TQADAGEYRC EAENEYGSAW TEGPIIVTLE GAPKIDGEAP DFLQPVKPAV VTVGETAVLE3300
 3301 GKISGKPKPS VKWYKNGEEL KPSDRVKIEN LDDGTQRLTV TNAKLDDMDE YRCEASNEFG3360
 3361 DVWSDVTLTV KEPAQVAPGF FKELSAIQVK ETETAKFECK VSGTKPDVKW FKDGTPLKED3420
 3421 KRVHFESTDD GTQRLVIEDS KTDDQGNYRI EVSNDAGVAN SKVPLTVVPS ETLKIKKGLT3480
 3481 DVNVTQGTKI LLSVEVEGKP KTVKWYKGTE TVTSSQTTKI VQVTESEYKL EIESAEMSDT3540
 3541 GAYRVVLSTD SFSVESSATV TVTKAAEKIS LPSFKKGLAD QSVPKGTPLV LEVEIEGKPK3600
 3601 DVKWYKNGDE IKDGKVEDLG NGKYRLTIPD FQEKDVGEYS VTAANEAGEI ESKAKVNVSA3660
 3661 KPEIVSGLVP TTVKQGETAT FNVKVKGPVK GVKWYKNGKE IPDAKTKDNG DGSYSLEIPN3720
 3721 AQVEDAADYK VVVSNDAGDA DSSAALTVKL ADDGKDKVKP EIVSGLIPTT VKQGETATFN3780
 3781 VKVKGPVKQV KWYKNGKEIP NAKAKDNGDG SYSLEIPNAQ LDDTADYKVV VSNDAGDADS3840
 3841 SAALTVKLPG IAIVKGLEDA EVPKGKKAVL QVETNKKPKE IKWYKNGKEI TPSDKAQPGS3900
 3901 DGDNKPQLVI PDAGDDDAAE YKVVLTDEDG NTADSSCALT VKLPAKEPKI IKGLEDQVVS3960
 3961 IGSPIKLEIE TSGSPKTVKW YKNGKELPGA AAKTIKIQKI DDNKYVLEIP SSVVEDTGDY4020
 4021 KVEVANEAGS ANSSGKITVE PKITFLKPLK DQSITEGENA EFSVETNTKP RIVKWYKNGQ4080
 4081 EIKPNSRFII EQKTDTKYQL VIKNAVRDDA DTYKIVLENT AGEAESSAQL TVKKAKAGLC4140
 4141 KIVKGLEDQV VAKGAKMVFE VKIQGEPEDV RWLRDANVIS AGANAIIEKI DDTTYRLIIP4200
 4201 SADLKDAGEY TVEVINESGK AKSDAKGEVD EKPEIVRGLE NIEIPEGDDD VFKVEVSAPV4260
 4261 RQVKWYKNDQ EIKPNSHLEA KKIGPKKYEL AINRAQLDDG ADYKVVLSNA AGDCDSSAAL4320
 4321 TVVKPNVLKI VDGLKDVDVE EPQPVELKVK VEGIPKVIKW YKNGQELKPD ADGFKFEEKP4380
 4381 ESGEFSLTIP SSKKSDGGAY RVVLGNDKGE VYSGSVVHVK SAKSSEPTSG ANFLSPLKDT4440
 4441 EVEEGDMLTL QCTIAGEPFP EVIWEKDGVV LQKDDRITMR VALDGTATLR IRSAKKSDIG4500
 4501 QYRVTAKNEA GSATSDCKVT VTEQGEQPSK PKFVIPLKTG AALPGDKKEF NVKVRGLPKP4560
 4561 TLQWFLNGIP IKFDDRITLD DMADGNYCLT IRDVREEDFG TLKCIAKNEN GTDETVCEFQ4620
 4621 QGAGHDDGSR DDLRYPPRFN VPLWDRRIPV GDPMFIECHV DANPTAEVEW FKDGKKIEHT4680
 4681 AHTEIRNTVD GACRIKIIPF EESDIGVYMC VAVNELGQAE TQATYQVEIL EHVEEEKRRE4740
 4741 YAPKINPPLE DKTVNGGQPI RLSCKVDAIP RASVVWYKDG LPLRADSRTS IQYEEDGTAT4800
 4801 LAINDSTEED IGAYRCVATN AHGTINTSCS VNVKVPKQEV KKEGEEPFFT KGLVDLWADR4860
 4861 GDSFTLKCAV TGDPFPEIKW YRNGQLLRNG PRTVIETSPD GSCSLTVNES TMSDEGIYRC4920
 4921 EAENAHGKAK TQATAHVQMA LGKTEKPKMD EGKPPKFILE LSDMSVSLGN VIDLECKVTG4980
 4981 LPNPSVKWSK DGGPLIEDSR FEWSNEASKG VYQLRIKNAT VHDEGTYRCV ATNENGSATT5040
 5041 KSFVRMDDGL GSGVVTASQP PRFTLKMGDV RTTEGQPLKL ECKVDASPLP EMVWYKDGAI5100
 5101 VTPSDRIQIS LSPDGVATLL IPSCVYDDDG IYRVIATNPS GTAQDKGTAT VKKLPRDSGA5160
 5161 RRSADRDVFD ANKAPKLMEP LENIRIPEKQ SFRLRCKFSG DPKPTIKWFK DGERVFPYGR5220
 5221 LQLIESPDGV CELVVDSATR QDAGGYRCVA ENTYGSARTS CDVNVIRGDR KPRDIDSSIR5280
 5281 EGKAPGFTTP LTIRRAKPGD SVTFECLPFG NPFPSIKWLK DGLELFSDEK IKMEAAADGT5340
 5341 QRLILSDVTF LSEGYFRCVA TNEHGTASTK AELVIEGDRT IGSRPLPEVN GEPEECKPRI5400
 5401 RRGLYNMSIH EGNVVEMIVC ATGIPTPTVK WYKDGQEIVG DGPDGKRVIF TDERGIHHLV5460
 5461 IVNASPDDEG EYSLEATNKL GSAKTEGSLN IIRPRHIADA DERGGMPFPP GFVRQLKNKH5520
 5521 VFNHMPTIFD CLVVGHPAPE VEWFHNGKKI VPGGRIKIQS CGGGSHALII LDTTLEDAGE5580
 5581 YVATAKNSHG SASSSAVLDV TVPFLDSIKF NGEIDVTPYL TEEYGFKKLN TASLPTPPDR5640
 5641 GPFIKEVTGH YLTLSWIPTK RAPPRYPQVT YVIEIRELPE KQWSLLEYNI PEPVCKVRNL5700
 5701 ELGKSYQFRV RAENIYGISD PSPASPPSRL MAPPQPVFDR RTNKVIPLLD PYAEKALDMR5760
 5761 YSEQYACAPW FSPGVVEKRY CAENDTLTIV LNVSGFPDPD IKWKFRGWDI DTSSPTSKCK5820
 5821 VYTYGGSETT LAITGFSKEN VGQYQCFAKN DYGDAQQNIM VDLATRPNFI QPLVNKTFSS5880
 5881 AQPMRMDVRV DGEPFPELKW MKEWRPIVES SRIKFVQDGP YLCSLIINDP MWRDSGIYSC5940
 5941 VAVNDAGQAT TSCTVTVEAE GDYNDVELPR RRVTIESRRV RELYEISEKD EK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle