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Protein Overview: LEPA_SHEON

General Information:
Name(s) found: LEPA_SHEON [Swiss-Prot]
Description(s) found:
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  • gi|24372924|ref|NP_716966.1| GTP-binding protein LepA [Shewanella oneidensis MR-1] [NCBI NR]
  • gi|24347056|gb|AAN54411.1|AE015578_11 GTP-binding protein LepA [Shewanella oneidensis MR-1] [NCBI NR]
  • Elongation factor 4 OS=Shewanella oneidensis (strain MR-1) GN=lepA PE=3 SV=1 [Swiss-Prot]
  • GTP-binding protein LepA [Shewanella oneidensis MR-1]gi|24347056|gb|AAN54411.1| GTP-binding protein LepA [Shewanella oneidensis MR-1]gi|33112372|sp|Q8EH83|LEPA_SHEON GTP-binding protein lepA [nrdb_11152004_Chlamydomonas]
  • GTP-binding protein LepA [Shewanella oneidensis MR-1] [nr-271106-contam.fasta]
    • Organism: Shewanella oneidensis MR-1
    Length: 596 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: biological_process [ND]
    Molecular Function: GTP binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKHIRNFSII AHIDHGKSTL SDRLIQVCGG LSDREMDAQV LDSMDLERER GITIKAQSVT  60
   61 LEYKAKNGEI YQLNFIDTPG HVDFSYEVSR SLAACEGALL VVDAGQGVEA QTLANCYTAL 120
  121 DMNLDVVPIL NKIDLPQADP ERVAAEIEDI VGIDAMNAVR CSAKTGVGID DVLEVIVEQI 180
  181 PPPEGNPDAP LQALIIDSWF DSYLGVVSLV RIKHGVLKKG DKFKVMSTGQ NHTADRVGIF 240
  241 TPKQTDKTEL KTGEVGFVIA GIKEIHGAPV GDTLTLAKNG ADKPLPGFKK VKPQVYAGVF 300
  301 PISTDEYENF RDALNKLSLN DASLFFEPES SSALGFGFRI GYLGLLHMEI IQERLEREYD 360
  361 LDLITTAPTV VYEVLMTSGE TIYVDNPADL PAINNIEEMR EPIVEANILV PKEYLGNVIT 420
  421 LCIEKRGTQV NMVYHGNQVA VTYHLPMAEV VMDFFDRLKS TSRGYASLEY NFIRFDPADM 480
  481 VRLDILINGD RVDALAMIIH RSNIRHRGLA LVEKMKELIP RQMFDIAIQA AVGSQIIARS 540
  541 TVKALRKDVT AKCYGGDVSR KKKLLNKQKE GKKRMKQVGN VEVPQEAFLA VLKLNE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..596] PSI-BLAST 101.0 Elongation factor G (EF-G), domain II; Elongation factor G (EF-G), N-terminal (G) domain; Elongation factor G (EF-G), domain IV; Elongation factor G (EF-G)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • structural constituent of ribosome
    		•  6.48160314495408 bayes_pls_golite062009
  • structural molecule activity
    		•  5.89785955477588 bayes_pls_golite062009
  • peptidyltransferase activity
    		•  2.36235718442873 bayes_pls_golite062009
  • translation elongation factor activity
    		•  1.78840251801545 bayes_pls_golite062009
  • mRNA binding
    		•  1.64128426760439 bayes_pls_golite062009
  • translation release factor activity
    		•  1.47279606301067 bayes_pls_golite062009
  • translation termination factor activity
    		•  1.47162484856171 bayes_pls_golite062009
  • RNA binding
    		•  1.40868766468494 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.30900892230008 bayes_pls_golite062009
  • protein binding
    		•  1.24158964059466 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.17107716081138 bayes_pls_golite062009
  • binding
    		•  1.0709940954148 bayes_pls_golite062009
  • DNA binding
    		•  0.911272650085046 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • motor activity
    		•  0.61636596887462 bayes_pls_golite062009
  • transcription activator activity
    		•  0.491297187941564 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.2302541318658 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.19921800066954 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.180372638853914 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.0716139935283535 bayes_pls_golite062009
  • transcription factor activity
    		•  0.0612932659603008 bayes_pls_golite062009
  • helicase activity
    		•  0.0450969969658499 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.0272673919333979 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  6.9430052008157E-5 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle