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Protein Overview: SYKM_YEAST

General Information:
Name(s) found: SYKM_YEAST [Swiss-Prot]
Description(s) found:
  • Lysine--tRNA ligase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSK1 PE=1 SV=3 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 576 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVLLKRRSL TFAPRWLWCK CRSSRSRPYS LAHAVDTSKM EATRRNGQIV KDLGRYYPSM  60
   61 SESALHDLCQ EYKEVTIADF NERFLGNPAT LHHEDNPNLL LSINGRIKSI RFSGQKIVFI 120
  121 DLYNGSSGLK NDTQLQLIVN YNKIGGSSED KANFSEYMNF LKKGDYIKAL GYPGFSQSRV 180
  181 KMLSLICNKL PIVLSVSQLP LPSRLNDETK IKSNRVVDYQ LNGTQTLLVR ARIIKLLRKF 240
  241 LDDRNFVEVE TPILSSKSNG AMAKPFITSS KDFDHLELRI APELWLKRLI ISGLQKVYEI 300
  301 GKVFRNEGID STHNAEFSTL EFYETYMSMD DIVTRTEDLF KFLITNLQKF FQDTRLPVPK 360
  361 TFSELHLALS ENNWKFRKVE FLPTLNKELG IDLMNSGLDI NKPSELLKAL PKDIAKKYFP 420
  421 SADNTGQLSS LQILNKLSDV FLEQRHCQST LPTVIYHQPA ILSPLAKTDP QNKQVTKRFE 480
  481 VFIKGKEYIN AYEEENCPQL QLQKFLQQKQ INELTGNKTE TLSPVIDYQY VETMKYGMPP 540
  541 VGGFGLGIDR LCMLFCDKKR IEEVLPFGCV DDVNRQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..204] PSI-BLAST 633.0103 Lysyl-tRNA synthetase (LysRS)
    2 View Details [205..576] PSI-BLAST 633.0103 Lysyl-tRNA synthetase (LysRS)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.89468709683036 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.89468709683036 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.88410036819636 bayes_pls_golite062009
  • ligase activity
    		•  6.92073480193262 bayes_pls_golite062009
  • lysine-tRNA ligase activity
    		•  5.79033103181143 bayes_pls_golite062009
  • phenylalanine-tRNA ligase activity
    		•  2.99105702052936 bayes_pls_golite062009
  • serine-tRNA ligase activity
    		•  2.46505535069103 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.43759174701552 bayes_pls_golite062009
  • glycine-tRNA ligase activity
    		•  2.29229136935761 bayes_pls_golite062009
  • threonine-tRNA ligase activity
    		•  2.18642354927 bayes_pls_golite062009
  • structural molecule activity
    		•  2.08258913217268 bayes_pls_golite062009
  • catalytic activity
    		•  1.99372273395202 bayes_pls_golite062009
  • alanine-tRNA ligase activity
    		•  1.82594054955281 bayes_pls_golite062009
  • histidine-tRNA ligase activity
    		•  1.72215103383322 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.67362693618722 bayes_pls_golite062009
  • binding
    		•  1.54403712698597 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.48056625237411 bayes_pls_golite062009
  • DNA binding
    		•  1.44496421928708 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.96756670903925 bayes_pls_golite062009
  • asparagine-tRNA ligase activity
    		•  0.921492123574877 bayes_pls_golite062009
  • transcription factor activity
    		•  0.825973629967327 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.77755643935497 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.702449673647117 bayes_pls_golite062009
  • nuclease activity
    		•  0.111225677144242 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
    		•  0.00572514744734753 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.81

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle