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Protein Overview: SET1_YEAST

General Information:
Name(s) found: SET1_YEAST [Swiss-Prot]
Description(s) found:
  • Histone-lysine N-methyltransferase, H3 lysine-4 specific OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SET1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1080 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNYYRRAHA SSGSYRQPQE QPQYSRSGHY QYSNGHSHQQ YSSQYNQRRR YNHNDGTRRR  60
   61 YNDDRPHSSN NASTRQYYAT NNSQSGPYVN KKSDISSRRG MSQSRYSNSN VHNTLASSSG 120
  121 SLPTESALLL QQRPPSVLRY NTDNLKSKFH YFDPIKGEFF NKDKMLSWKA TDKEFSETGY 180
  181 YVVKELQDGQ FKFKIKHRHP EIKASDPRNE NGIMTSGKVA THRKCRNSLI LLPRISYDRY 240
  241 SLGPPPSCEI VVYPAQDSTT TNIQDISIKN YFKKYGEISH FEAFNDPNSA LPLHVYLIKY 300
  301 ASSDGKINDA AKAAFSAVRK HESSGCFIMG FKFEVILNKH SILNNIISKF VEINVKKLQK 360
  361 LQENLKKAKE KEAENEKAKE LQGKDITLPK EPKVDTLSHS SGSEKRIPYD LLGVVNNRPV 420
  421 LHVSKIFVAK HRFCVEDFKY KLRGYRCAKF IDHPTGIYII FNDIAHAQTC SNAESGNLTI 480
  481 MSRSRRIPIL IKFHLILPRF QNRTRFNKSS SSSNSTNVPI KYESKEEFIE ATAKQILKDL 540
  541 EKTLHVDIKK RLIGPTVFDA LDHANFPELL AKRELKEKEK RQQIASKIAE DELKRKEEAK 600
  601 RDFDLFGLYG GYAKSNKRNL KRHNSLALDH TSLKRKKLSN GIKPMAHLLN EETDSKETTP 660
  661 LNDEGITRVS KEHDEEDENM TSSSSEEEEE EAPDKKFKSE SEPTTPESDH LHGIKPLVPD 720
  721 QNGSSDVLDA SSMYKPTATE IPEPVYPPEE YDLKYSQTLS SMDLQNAIKD EEDMLILKQL 780
  781 LSTYTPTVTP ETSAALEYKI WQSRRKVLEE EKASDWQIEL NGTLFDSELQ PGSSFKAEGF 840
  841 RKIADKLKIN YLPHRRRVHQ PLNTVNIHNE RNEYTPELCQ REESSNKEPS DSVPQEVSSS 900
  901 RDNRASNRRF QQDIEAQKAA IGTESELLSL NQLNKRKKPV MFARSAIHNW GLYALDSIAA 960
  961 KEMIIEYVGE RIRQPVAEMR EKRYLKNGIG SSYLFRVDEN TVIDATKKGG IARFINHCCD1020
 1021 PNCTAKIIKV GGRRRIVIYA LRDIAASEEL TYDYKFEREK DDEERLPCLC GAPNCKGFLN1080
 1081

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..286] deduced N/A No confident structure predictions are available.
    2 View Details [287..807] MSA 22.272997 View MSA. No confident structure predictions are available.
    3 View Details [808..901] deduced N/A No confident structure predictions are available.
    4 View Details [902..1080] Pfam 62.69897 SET domain No confident structure predictions are available.
    5 View Details [734..809] deduced N/A No confident structure predictions are available.
    6 View Details [810..1080] PSI-BLAST 61.69897 No description for 2r3aA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • nucleic acid binding
    		•  4.65259034341669 bayes_pls_golite062009
  • binding
    		•  3.48033873254013 bayes_pls_golite062009
  • RNA binding
    		•  2.51560202858525 bayes_pls_golite062009
  • telomeric DNA binding
    		•  2.47873883381637 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.2045206027152 bayes_pls_golite062009
  • DNA binding
    		•  1.99030664201171 bayes_pls_golite062009
  • mRNA binding
    		•  1.52376515340629 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.26023364760328 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.19033433766236 bayes_pls_golite062009
  • transcription factor activity
    		•  1.09958329302628 bayes_pls_golite062009
  • protein binding
    		•  1.05805521997665 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.866729044067453 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.715114913338408 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.633093884585572 bayes_pls_golite062009
    		• 0.612296958107081 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.327072171076297 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle