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Protein Overview: NTH2_YEAST

General Information:
Name(s) found: NTH2_YEAST [Swiss-Prot]
Description(s) found:
Found 2 descriptions.
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  • Endonuclease III homolog 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NTG2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 380 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREESRSRKR KHIPVDIEEV EVRSKYFKKN ERTVELVKEN KINKDLQNYG GVNIDWIKAL  60
   61 KPIEYFEWIE SRTCDDPRTW GRPITKEEMI NDSGAKVPES FLPIYNRVRL MRSKVKTPVD 120
  121 AMGCSMIPVL VSNKCGIPSE KVDPKNFRLQ FLIGTMLSAQ TRDERMAQAA LNITEYCLNT 180
  181 LKIAEGITLD GLLKIDEPVL ANLIRCVSFY TRKANFIKRT AQLLVDNFDS DIPYDIEGIL 240
  241 SLPGVGPKMG YLTLQKGWGL IAGICVDVHV HRLCKMWNWV DPIKCKTAEH TRKELQVWLP 300
  301 HSLWYEINTV LVGFGQLICM ARGKRCDLCL ANDVCNARNE KLIESSKFHQ LEDKEDIEKV 360
  361 YSHWLDTVTN GITTERHKKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..97] deduced N/A No confident structure predictions are available.
    2 View Details [98..140]
    [250..380]    		 PSI-BLAST 170.927757 Endonuclease III
    3 View Details [141..249] PSI-BLAST 170.927757 Endonuclease III

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • DNA N-glycosylase activity
    		•  4.8124964619976 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing N-glycosyl compounds
    		•  4.26870112679392 bayes_pls_golite062009
  • DNA-(apurinic or apyrimidinic site) lyase activity
    		•  3.71152530486175 bayes_pls_golite062009
  • oxidized base lesion DNA N-glycosylase activity
    		•  2.49872706126491 bayes_pls_golite062009
  • hydrolase activity
    		•  2.39042189031819 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  2.24777884454113 bayes_pls_golite062009
  • catalytic activity
    		•  2.13345932727422 bayes_pls_golite062009
  • alkylbase DNA N-glycosylase activity
    		•  1.5832578018127 bayes_pls_golite062009
  • DNA binding
    		•  1.44394874535958 bayes_pls_golite062009
  • 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity
    		•  1.41538804527379 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.36800347239439 bayes_pls_golite062009
  • damaged DNA binding
    		•  1.32391480975295 bayes_pls_golite062009
  • binding
    		•  1.15752946565805 bayes_pls_golite062009
  • DNA-3-methyladenine glycosylase I activity
    		•  1.06383943982125 bayes_pls_golite062009
  • oxidized pyrimidine base lesion DNA N-glycosylase activity
    		•  0.889914753262716 bayes_pls_golite062009
  • uracil DNA N-glycosylase activity
    		•  0.879508131574476 bayes_pls_golite062009
  • oxidized purine base lesion DNA N-glycosylase activity
    		•  0.789032002944782 bayes_pls_golite062009
  • purine-specific mismatch base pair DNA N-glycosylase activity
    		•  0.68578837518217 bayes_pls_golite062009
  • mismatch base pair DNA N-glycosylase activity
    		•  0.661651574677137 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.493252955870142 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.32094102946624 bayes_pls_golite062009
  • protein binding
    		•  0.0921713980805489 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.0676784802238829 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.0420287478494503 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle