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Protein Overview: MET18_YEAST

General Information:
Name(s) found: MET18_YEAST [Swiss-Prot]
Description(s) found:
  • DNA repair/transcription protein MET18/MMS19 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET18 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1032 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPDELNSAV VTFMANLNID DSKANETAST VTDSIVHRSI KLLEVVVALK DYFLSENEVE  60
   61 RKKALTCLTT ILAKTPKDHL SKNECSVIFQ FYQSKLDDQA LAKEVLEGFA ALAPMKYVSI 120
  121 NEIAQLLRLL LDNYQQGQHL ASTRLWPFKI LRKIFDRFFV NGSSTEQVKR INDLFIETFL 180
  181 HVANGEKDPR NLLLSFALNK SITSSLQNVE NFKEDLFDVL FCYFPITFKP PKHDPYKISN 240
  241 QDLKTALRSA ITATPLFAED AYSNLLDKLT ASSPVVKNDT LLTLLECVRK FGGSSILENW 300
  301 TLLWNALKFE IMQNSEGNEN TLLNPYNKDQ QSDDVGQYTN YDACLKIINL MALQLYNFDK 360
  361 VSFEKFFTHV LDELKPNFKY EKDLKQTCQI LSAIGSGNVE IFNKVISSTF PLFLINTSEV 420
  421 AKLKLLIMNF SFFVDSYIDL FGRTSKESLG TPVPNNKMAE YKDEIIMILS MALTRSSKAE 480
  481 VTIRTLSVIQ FTKMIKMKGF LTPEEVSLII QYFTEEILTD NNKNIYYACL EGLKTISEIY 540
  541 EDLVFEISLK KLLDLLPDCF EEKIRVNDEE NIHIETILKI ILDFTTSRHI LVKESITFLA 600
  601 TKLNRVAKIS KSREYCFLLI STIYSLFNNN NQNENVLNEE DALALKNAIE PKLFEIITQE 660
  661 SAIVSDNYNL TLLSNVLFFT NLKIPQAAHQ EELDRYNELF ISEGKIRILD TPNVLAISYA 720
  721 KILSALNKNC QFPQKFTVLF GTVQLLKKHA PRMTETEKLG YLELLLVLSN KFVSEKDVIG 780
  781 LFDWKDLSVI NLEVMVWLTK GLIMQNSLES SEIAKKFIDL LSNEEIGSLV SKLFEVFVMD 840
  841 ISSLKKFKGI SWNNNVKILY KQKFFGDIFQ TLVSNYKNTV DMTIKCNYLT ALSLVLKHTP 900
  901 SQSVGPFIND LFPLLLQALD MPDPEVRVSA LETLKDTTDK HHTLITEHVS TIVPLLLSLS 960
  961 LPHKYNSVSV RLIALQLLEM ITTVVPLNYC LSYQDDVLSA LIPVLSDKKR IIRKQCVDTR1020
 1021 QVYYELGQIP FE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..207] MSA 2.010957 View MSA. No confident structure predictions are available.
    2 View Details [208..458] deduced N/A No confident structure predictions are available.
    3 View Details [459..849] MSA 1.013918 View MSA. No confident structure predictions are available.
    4 View Details [850..1032] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.96084803796407 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.2915564382469 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.19067997822967 bayes_pls_golite062009
  • DNA binding
    		•  1.71679738414596 bayes_pls_golite062009
  • protein binding
    		•  1.61131270705552 bayes_pls_golite062009
  • transcription factor activity
    		•  1.01026749293758 bayes_pls_golite062009
  • structural molecule activity
    		•  0.851103372489505 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.384349606267362 bayes_pls_golite062009
  • translation regulator activity
    		•  0.378889783888265 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.348192604482187 bayes_pls_golite062009
  • RNA binding
    		•  0.243875756041061 bayes_pls_golite062009
  • transcription activator activity
    		•  0.142253868848261 bayes_pls_golite062009
  • transcription factor binding
    		•  8.79739237675814E-4 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle