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Protein Overview: LAA1_YEAST

General Information:
Name(s) found: LAA1_YEAST [Swiss-Prot]
Description(s) found:
  • AP-1 accessory protein LAA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LAA1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 2014 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANRSLKKVI ETSSNNGHDL LTWITTNLEK LICLKEVNDN EIQEVKEIHT QLDEFVRYIS  60
   61 VLENTDDLEL HSVFISLSQL YTISIWRLKD EYPGVVFDSA AFLTNVLCEE DVSIDDGDTD 120
  121 PNQKKKKKKS STKKKKYIYS PAKDIACTIL VQLFENFGSS ISSLIPLLFN AIFKNLKKIM 180
  181 EKSKYYHATF MTTLLQLFNA ILRNSNNDDK ILDPATYAKF SKLSKTVFDS ISTDEKDFSV 240
  241 TFVSVLIECW TAHFKQTNFI REHSHDIIET IYSRFTEGEI GVYGFANDET RIFTAKSLAE 300
  301 ILFDYYFSKN ILTLQEVWSI YVKIFLNCDT RDVESGCFES IIHLINLNLL ADNTFLSNSK 360
  361 YLDIVLSLSG VFSSYEVNNR SMNTLSRYLR YFQHMHEVIL PHLNDSAKTQ MLYYILGCSD 420
  421 TYQSSSKSDS ASNFKYSIDA KPETQWLTLL QLDFTYVLIS DLGSTFTTEE NTVKEIRDKL 480
  481 VDLATCEIFT IRVHTVEILK VFLNNCPEYL SETIENSLRA LSTDFKSTGK FIFHKNHGHA 540
  541 FIIANLIKGA ESDYISYELI MRITVFSTSF IKNNTTSTSS NLYFKGLLCW ILLIGLMNYK 600
  601 DEQYLKLQIP QLFLFWKVLL THTYTYHDED ELYKNLEIRN HALTCLLTYL SNTTIDKEMA 660
  661 KQVSYLLTKC SNFNHSIDLK SKNIDNALLH NENRILQVYL KLEKYINSDF NSSLLILIVK 720
  721 NFSDPNLYTE SSSSVLGSLK DIGNRKVSNK DDMESNIVLE SSINTLLRQN NGFAFGLSSK 780
  781 ITGDRIVNLS MSSAYKYDES ISGSWPSKDY NWYNIFEVEV SKPISPILSL DSLILLYGSG 840
  841 SYSQIDRYAP QVTTSLIDSS MELFSSVFPF LNSKIQYSIM ETLNLSMFSK MTTPLRSVAV 900
  901 AANVCSALHN ALRIMQENNL ELDYSVGQLI IESIKKIQFF NDIFLTKIKA DCVGLLTAAI 960
  961 ARTLGDEERQ KFLTEQSRIF IKNVADMDEP YLRMFHVLSL ATIFKYNSQY ANFEEYFDVI1020
 1021 FALMRDPHPV VHSWSLKAMH ILLEKHLVID LKTAALLLSS MEELLVQDKY GIYGRSTLRC1080
 1081 NYNRDFNSHV AIGEISRTLT ETVGPNFLEL NTKVLDSFRN ITLSMLISNN ILNSITSIKM1140
 1141 FENIATFKMK NILNYEIFIL ASKSIIKSSI VTGIGSSYFD TTFTGSNELI SRTSSLKGAF1200
 1201 ENFDLLTLLY KLQMEEFFMK EMENLSWRYL ALFPNSGSVK NYFTEWILHT FKRDNHWFDK1260
 1261 LYSIFNMSLG RLFQSYNRDV SALLEVNGLK KSSEKEIKGE EEESIANVNQ LTDTDAGGLD1320
 1321 SENLQWKSRQ IILNLILMLC LESEKYENLL LALSNKIADL IKISFRGSTV RNEGMKLTGL1380
 1381 HILNFVLKNY STMRDPQVPG SSILEQQEAQ ITSALMPAFS KGSSPTVMSF AITVAAEVLA1440
 1441 SNIMPPDKLG RISQLLIDLL GNFKDPNSGI RIGEAIIVTP KAKRKIELAV LDAWAEVVQR1500
 1501 SITSSNDALF SFTRKYWSIL VPLWIISLRE YMMIKYNDND STVQVKNDSK ENSLIEPRST1560
 1561 KIELYEPVWL NFVEALGCTL DSDVQVILAS LNDEELEYFL FILFSQCLEA IVKNIDDHSV1620
 1621 KMQVLPALHN VLKSNLCIKS IFEDDIITEV VEIMDRLIST GDSKEEFLLV DIISDLIIGY1680
 1681 SKCNATPETF LQDIDKLYEL LRLLMTIISE RLPFIKYNVL TSEEDDNEIK ISPTDISLLK1740
 1741 KTFIAFESNI SNFDNMFKVD LYSCLLFIIG KIYECSHREV IIPIILPLFK ALVKALTESE1800
 1801 DEKNIVLLEI FYGSIKDVIY HKLDSKNKVA TILILLSNGY SKLSFQELNQ CANILSEALN1860
 1861 NPATQPIALQ GFKRIISNIF KYPLLQYFMK LVIKRFFQDI QTNDSLSQAS IKTKLIIQFS1920
 1921 EEVIKQDHQK ASLSIALCLS FFAAYHSAYT EKIDNEVASG IVALAKLDKN SFKEAISSTI1980
 1981 SPQQKAIIGS VMEAYVKSQS LGSVEEAFQL KSFD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..1286] deduced N/A No confident structure predictions are available.
    2 View Details [1287..1473] MSA 1.007958 View MSA. No confident structure predictions are available.
    3 View Details [1474..1838] MSA 1.009949 View MSA. No confident structure predictions are available.
    4 View Details [1839..2014] deduced N/A No confident structure predictions are available.
    5 View Details [551..780] deduced N/A No confident structure predictions are available.
    6 View Details [781..842] deduced N/A No confident structure predictions are available.
    7 View Details [843..1554] FFAS03 1.19 Adaptin beta subunit N-terminal fragment
    8 View Details [1555..1684] MSA 2.05697 View MSA. No confident structure predictions are available.
    9 View Details [1685..1802] deduced N/A No confident structure predictions are available.
    10 View Details [1803..1881] deduced N/A No confident structure predictions are available.
    11 View Details [1882..2014] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7
    Term Confidence Notes
  • clathrin binding
    		•  4.44172446279719 bayes_pls_golite062009
  • protein transporter activity
    		•  3.8871835220517 bayes_pls_golite062009
  • transporter activity
    		•  2.3766833486706 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.12926593993985 bayes_pls_golite062009
  • binding
    		•  2.08129940242136 bayes_pls_golite062009
  • protein binding
    		•  2.0097220759196 bayes_pls_golite062009
  • structural molecule activity
    		•  1.70115473462412 bayes_pls_golite062009
  • signal sequence binding
    		•  1.53212344797955 bayes_pls_golite062009
  • RNA binding
    		•  1.423416093612 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.2724388835449 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.04982314606251 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  0.824035252349223 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.260663498540354 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.256036243669218 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.234271600707329 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.225395946682209 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.186601655036333 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.183072614802483 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.182751938544977 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.15186105020367 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.109435859778099 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0728493557966827 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0641324729536009 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.0615190129942244 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0475280280823402 bayes_pls_golite062009
    8 No functions predicted.
    9 No functions predicted.
    10 No functions predicted.
    11 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle