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Protein Overview: APC2_YEAST

General Information:
Name(s) found: APC2_YEAST [Swiss-Prot]
Description(s) found:
  • Anaphase-promoting complex subunit 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APC2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 853 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFQITPTRD LKVITDELQT LSSYIFHTNI VDDLNSLLTW MSPNDAKSNH QLRPPSLRIK  60
   61 NIIKVLFPNN ATTSPYSMIN TSQANNSIVN EGNTNKELQL QLFSTLKEFY IFQVRYHFFL 120
  121 HFNNINYLKD IQRWENYYEF PLRYVPIFDV NVNDWALELN SLRHYLLNRN IKFKNNLRTR 180
  181 LDKLIMDDDF DLADNLIQWL KSANGSLSST ELIVNALYSK INKFCEDNMS RVWNKRFMIM 240
  241 ETFNKFINQY WSQFSKLVGC PEDDHELTTT VFNCFESNFL RIRTNEIFDI CVLAYPDSKV 300
  301 TLLELRKIMK DFKDYTNIVT TFLSDFKKYI LNPSVTTVDA LLRYVKTIKA FLVLDPTGRC 360
  361 LHSITTFVKP YFQERKHLVN VLLYAMLDLP EEELKEKINF NVDMKALLSL VDTLHDSDIN 420
  421 QDTNITKRDK NKKSPFLWNL KVKGKRELNK DLPIRHAMLY EHILNYYIAW VPEPNDMIPG 480
  481 NIKSSYIKTN LFEVLLDLFE SREFFISEFR NLLTDRLFTL KFYTLDEKWT RCLKLIREKI 540
  541 VKFTETSHSN YITNGILGLL ETTAPAADAD QSNLNSIDVM LWDIKCSEEL CRKMHEVAGL 600
  601 DPIIFPKFIS LLYWKYNCDT QGSNDLAFHL PIDLERELQK YSDIYSQLKP GRKLQLCKDK 660
  661 GKVEIQLAFK DGRKLVLDVS LEQCSVINQF DSPNDEPICL SLEQLSESLN IAPPRLTHLL 720
  721 DFWIQKGVLL KENGTYSVIE HSEMDFDQAQ KTAPMEIENS NYELHNDSEI ERKYELTLQR 780
  781 SLPFIEGMLT NLGAMKLHKI HSFLKITVPK DWGYNRITLQ QLEGYLNTLA DEGRLKYIAN 840
  841 GSYEIVKNGH KNS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..93] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [94..186] MSA 1.05099 View MSA. Confident ab initio structure predictions are available.
    3 View Details [187..406] MSA 2.071982 View MSA. No confident structure predictions are available.
    4 View Details [407..758] deduced N/A No confident structure predictions are available.
    5 View Details [759..853] PSI-BLAST 375.64593 Anaphase promoting complex (APC)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  9.47178230940453 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  9.15192834197166 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  8.12051073361876 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  6.87003086224111 bayes_pls_golite062009
  • ligase activity
    		•  4.85660414833673 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.44907471960058 bayes_pls_golite062009
  • transcription factor activity
    		•  3.48782936574155 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.39237599101586 bayes_pls_golite062009
  • binding
    		•  2.3219000606044 bayes_pls_golite062009
  • transcription activator activity
    		•  1.79615705315806 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.31024813110778 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.2152419300113 bayes_pls_golite062009
  • protein binding
    		•  1.15192193279649 bayes_pls_golite062009
  • DNA binding
    		•  1.05574145691051 bayes_pls_golite062009
  • vasopressin activated calcium mobilizing receptor activity
    		•  0.416181464241621 bayes_pls_golite062009
  • transcription factor binding
    		•  0.31161141447305 bayes_pls_golite062009
  • catalytic activity
    		•  0.201606344181603 bayes_pls_golite062009
  • hydrolase activity
    		•  0.140191206949582 bayes_pls_golite062009
  • specific transcriptional repressor activity
    		•  0.0565989703351002 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle