| Protein: | APC2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 853 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APC2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..853] | [1..853] |
|
|
0.0 | [34..838] | [17..773] |
|
|
0.0 | [34..838] | [17..773] |
|
|
0.0 | [32..839] | [18..767] |
|
|
0.0 | [33..832] | [10..742] |
|
|
0.0 | [62..832] | [55..771] |
|
|
0.0 | [33..838] | [15..771] |
|
|
0.0 | [34..838] | [15..767] |
|
Region A: Residues: [1-93] |
1 11 21 31 41 51
| | | | | |
1 MSFQITPTRD LKVITDELQT LSSYIFHTNI VDDLNSLLTW MSPNDAKSNH QLRPPSLRIK 60
61 NIIKVLFPNN ATTSPYSMIN TSQANNSIVN EGN
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.474 | 0.967 | mitotic spindle elongation | a.4.5 | "Winged helix" DNA-binding domain |
| Term | Confidence | Notes |
| ubiquitin-protein ligase activity | 9.47178230940453 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 9.15192834197166 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 8.12051073361876 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 6.87003086224111 | bayes_pls_golite062009 |
| ligase activity | 4.85660414833673 | bayes_pls_golite062009 |
| transcription regulator activity | 4.44907471960058 | bayes_pls_golite062009 |
| transcription factor activity | 3.48782936574155 | bayes_pls_golite062009 |
| transcription repressor activity | 2.39237599101586 | bayes_pls_golite062009 |
| binding | 2.3219000606044 | bayes_pls_golite062009 |
| transcription activator activity | 1.79615705315806 | bayes_pls_golite062009 |
| nucleic acid binding | 1.31024813110778 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 1.2152419300113 | bayes_pls_golite062009 |
| protein binding | 1.15192193279649 | bayes_pls_golite062009 |
| DNA binding | 1.05574145691051 | bayes_pls_golite062009 |
| vasopressin activated calcium mobilizing receptor activity | 0.416181464241621 | bayes_pls_golite062009 |
| transcription factor binding | 0.31161141447305 | bayes_pls_golite062009 |
| catalytic activity | 0.201606344181603 | bayes_pls_golite062009 |
| hydrolase activity | 0.140191206949582 | bayes_pls_golite062009 |
| specific transcriptional repressor activity | 0.0565989703351002 | bayes_pls_golite062009 |
|
Region A: Residues: [94-186] |
1 11 21 31 41 51
| | | | | |
1 TNKELQLQLF STLKEFYIFQ VRYHFFLHFN NINYLKDIQR WENYYEFPLR YVPIFDVNVN 60
61 DWALELNSLR HYLLNRNIKF KNNLRTRLDK LIM
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.672 | 0.933 | mitotic spindle elongation | a.4.5 | "Winged helix" DNA-binding domain |
|
Region A: Residues: [187-406] |
1 11 21 31 41 51
| | | | | |
1 DDDFDLADNL IQWLKSANGS LSSTELIVNA LYSKINKFCE DNMSRVWNKR FMIMETFNKF 60
61 INQYWSQFSK LVGCPEDDHE LTTTVFNCFE SNFLRIRTNE IFDICVLAYP DSKVTLLELR 120
121 KIMKDFKDYT NIVTTFLSDF KKYILNPSVT TVDALLRYVK TIKAFLVLDP TGRCLHSITT 180
181 FVKPYFQERK HLVNVLLYAM LDLPEEELKE KINFNVDMKA
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [407-758] |
1 11 21 31 41 51
| | | | | |
1 LLSLVDTLHD SDINQDTNIT KRDKNKKSPF LWNLKVKGKR ELNKDLPIRH AMLYEHILNY 60
61 YIAWVPEPND MIPGNIKSSY IKTNLFEVLL DLFESREFFI SEFRNLLTDR LFTLKFYTLD 120
121 EKWTRCLKLI REKIVKFTET SHSNYITNGI LGLLETTAPA ADADQSNLNS IDVMLWDIKC 180
181 SEELCRKMHE VAGLDPIIFP KFISLLYWKY NCDTQGSNDL AFHLPIDLER ELQKYSDIYS 240
241 QLKPGRKLQL CKDKGKVEIQ LAFKDGRKLV LDVSLEQCSV INQFDSPNDE PICLSLEQLS 300
301 ESLNIAPPRL THLLDFWIQK GVLLKENGTY SVIEHSEMDF DQAQKTAPME IE
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [759-853] |
1 11 21 31 41 51
| | | | | |
1 NSNYELHNDS EIERKYELTL QRSLPFIEGM LTNLGAMKLH KIHSFLKITV PKDWGYNRIT 60
61 LQQLEGYLNT LADEGRLKYI ANGSYEIVKN GHKNS
|
| Detection Method: | |
| Confidence: | 375.64593 |
| Match: | 1lddA_ |
| Description: | Anaphase promoting complex (APC) |
Matching Structure (courtesy of the PDB): |
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