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Protein Overview: GCN5_ARATH

General Information:
Name(s) found: GCN5_ARATH [Swiss-Prot]
Description(s) found:
Found 14 descriptions.
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  • Histone acetyltransferase GCN5 OS=Arabidopsis thaliana GN=HAG1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 568 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    histone acetyltransferase complex [IPI]
    Biological Process: flower development [IMP]
    positive regulation of transcription [TAS]
    histone acetylation [IDA]
    response to light stimulus [IMP]
    root morphogenesis [IMP]
    Molecular Function: histone acetyltransferase activity [IDA][ISS]
    DNA binding [IDA]
    H3 histone acetyltransferase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSHSSHLNA ANRSRSSQTP SPSHSASASV TSSLHKRKLA ATTAANAAAS EDHAPPSSSF  60
   61 PPSSFSADTR DGALTSNDEL ESISARGADT DSDPDESEDI VVDDDEDEFA PEQDQDSSIR 120
  121 TFTAARLDSS SGVNGSSRNT KLKTESSTVK LESSDGGKDG GSSVVGTGVS GTVGGSSISG 180
  181 LVPKDESVKV LAENFQTSGA YIAREEALKR EEQAGRLKFV CYSNDSIDEH MMCLIGLKNI 240
  241 FARQLPNMPK EYIVRLLMDR KHKSVMVLRG NLVVGGITYR PYHSQKFGEI AFCAITADEQ 300
  301 VKGYGTRLMN HLKQHARDVD GLTHFLTYAD NNAVGYFVKQ GFTKEIYLEK DVWHGFIKDY 360
  361 DGGLLMECKI DPKLPYTDLS SMIRQQRKAI DERIRELSNC QNVYPKIEFL KNEAGIPRKI 420
  421 IKVEEIRGLR EAGWTPDQWG HTRFKLFNGS ADMVTNQKQL NALMRALLKT MQDHADAWPF 480
  481 KEPVDSRDVP DYYDIIKDPI DLKVIAKRVE SEQYYVTLDM FVADARRMFN NCRTYNSPDT 540
  541 IYYKCATRLE THFHSKVQAG LQSGAKSQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..213] MSA 16.150997 View MSA. No confident structure predictions are available.
    2 View Details [214..371] PSI-BLAST 75.221849 Catalytic domain of GCN5 histone acetyltransferase
    3 View Details [372..568] PSI-BLAST 30.39794 TAFII250 double bromodomain module

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • N-acetyltransferase activity
    		•  10.330867741687 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  10.2385402730839 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  10.2385402730839 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  10.2097972775096 bayes_pls_golite062009
  • acetyltransferase activity
    		•  9.5414870492393 bayes_pls_golite062009
  • acyltransferase activity
    		•  8.84144467104026 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  8.80032457938662 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  8.58458341779614 bayes_pls_golite062009
    		• 7.30820970670781 bayes_pls_golite062009
    		• 3.86052919290021 bayes_pls_golite062009
  • H3 histone acetyltransferase activity
    		•  3.27931674770011 bayes_pls_golite062009
  • transferase activity
    		•  2.87429355361226 bayes_pls_golite062009
  • catalytic activity
    		•  1.97933499002461 bayes_pls_golite062009
  • binding
    		•  1.07749536895426 bayes_pls_golite062009
  • glycylpeptide N-tetradecanoyltransferase activity
    		•  0.774009286200155 bayes_pls_golite062009
  • myristoyltransferase activity
    		•  0.774009286200155 bayes_pls_golite062009
  • histone binding
    		•  0.582104626133107 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.522132859536345 bayes_pls_golite062009
  • protein binding
    		•  0.283213965640071 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0766125702622449 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.0504023697864295 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle